GNOM vs. GERM

Last updated Jun 26, 2026

GNOM (Global X Genomics & Biotechnology ETF) and GERM (Amplify Treatments, Testing and Advancements ETF) are both Health & Biotech Equities funds - GNOM tracks the Solactive Genomics Index while GERM tracks the Prime Treatments, Testing and Advancements Index. Both are passively managed. Over the past year, GNOM returned 66.61% vs 0.00% for GERM. GNOM charges 0.50%/yr vs 0.68%/yr for GERM.

Performance

GNOM vs. GERM - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Global X Genomics & Biotechnology ETF (GNOM) and Amplify Treatments, Testing and Advancements ETF (GERM). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

GNOM

• 1D: 2.19%
• 1M: 16.88%
• YTD: 20.90%
• 6M: 16.82%
• 1Y: 66.61%
• 3Y*: 4.83%
• 5Y*: -10.28%
• 10Y*: —

GERM

• 1D: 0.00%
• 1M: 0.00%
• YTD: 0.00%
• 6M: 0.00%
• 1Y: 0.00%
• 3Y*: —
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

GNOM vs. GERM - Yearly Performance Comparison

	2026 (YTD)	2025	2024
GNOM Global X Genomics & Biotechnology ETF	20.90%	18.65%	-11.57%
GERM Amplify Treatments, Testing and Advancements ETF	0.00%	0.00%	0.00%

GNOM vs. GERM - Sectors Allocation Comparison

Sectors	GNOM	GERM
Healthcare	99.7%	99.3%
Technology	0.3%	-
Basic Materials	-	-
Communication Services	-	-
Consumer Cyclical	-	-
Consumer Defensive	-	-
Energy	-	-
Financial Services	-	0.4%
Industrials	-	-
Real Estate	-	-
Utilities	-	-

Return for Risk

GNOM vs. GERM — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

GNOM

GNOM Risk / Return Rank: 78
GNOM Sharpe Ratio Rank: 87
GNOM Sortino Ratio Rank: 85
GNOM Omega Ratio Rank: 74
GNOM Calmar Ratio Rank: 80
GNOM Martin Ratio Rank: 67

GERM

Risk / return metrics aren't available yet — we need at least 12 months of trading data to calculate them.

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

GNOM vs. GERM - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Global X Genomics & Biotechnology ETF (GNOM) and Amplify Treatments, Testing and Advancements ETF (GERM). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	GNOM	GERM	Difference
Sharpe ratio: Return per unit of total volatility	2.44	—	—
Sortino ratio: Return per unit of downside risk	3.28	—	—
Omega ratio: Gain probability vs. loss probability	1.38	—	—
Calmar ratio: Return relative to maximum drawdown	3.68	—	—
Martin ratio: Return relative to average drawdown	10.57	—	—

Drawdowns

GNOM vs. GERM - Drawdown Comparison

The maximum GNOM drawdown since its inception was -75.00%, which is greater than GERM's maximum drawdown of 0.00%. Use the drawdown chart below to compare losses from any high point for GNOM and GERM.

Drawdown Indicators

	GNOM	GERM	Difference
Max Drawdown Largest peak-to-trough decline	-75.00%	0.00%	-75.00%
Max Drawdown (1Y) Largest decline over 1 year	-18.17%	0.00%	-18.17%
Max Drawdown (3Y) Largest decline over 3 years	-44.24%	—	—
Max Drawdown (5Y) Largest decline over 5 years	-72.29%	—	—
Current Drawdown Current decline from peak	-50.04%	0.00%	-50.04%
Average Drawdown Average peak-to-trough decline	-40.64%	0.00%	-40.64%
Ulcer Index Depth and duration of drawdowns from previous peaks	6.32%	0.00%	+6.32%

Volatility

GNOM vs. GERM - Volatility Comparison

Global X Genomics & Biotechnology ETF (GNOM) has a higher volatility of 9.74% compared to Amplify Treatments, Testing and Advancements ETF (GERM) at 0.00%. This indicates that GNOM's price experiences larger fluctuations and is considered to be riskier than GERM based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	GNOM	GERM	Difference
Volatility (1M) Calculated over the trailing 1-month period	9.74%	0.00%	+9.74%
Volatility (6M) Calculated over the trailing 6-month period	20.61%	0.00%	+20.61%
Volatility (1Y) Calculated over the trailing 1-year period	27.40%	0.00%	+27.40%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	33.70%	0.00%	+33.70%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	34.18%	0.00%	+34.18%

GNOM vs. GERM - Expense Ratio Comparison

GNOM has a 0.50% expense ratio, which is lower than GERM's 0.68% expense ratio.

Dividends

GNOM vs. GERM - Dividend Comparison

GNOM's dividend yield for the trailing twelve months is around 1.14%, while GERM has not paid dividends to shareholders.

Position	TTM	2025	2024	2023	2022	2021	2020
GERM Amplify Treatments, Testing and Advancements ETF	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
GNOM Global X Genomics & Biotechnology ETF	1.14%	1.37%	0.00%	0.00%	0.00%	0.03%	0.14%

Frequently Asked Questions

Which is riskier, GNOM or GERM?

GNOM has higher volatility (9.74%) compared to GERM (0.00%). In terms of maximum drawdown, GNOM dropped -75.00% vs GERM's 0.00%.

Which ETF is better, GNOM or GERM?

On 1-year performance, GNOM leads with 66.61% vs 0.00% for GERM. On fees, GNOM is cheaper at 0.50% per year. On volatility, GERM has been the lower-risk option at 0.00%. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF has performed better, GNOM or GERM?

Over the 1-year period, GNOM has performed better with a 66.61% return vs 0.00%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.

Which ETF is cheaper, GNOM or GERM?

GNOM is cheaper with a 0.50% expense ratio, compared with 0.68% for GERM.

Which ETF pays a higher dividend yield, GNOM or GERM?

GNOM has the higher dividend yield at 1.14%, compared with 0.00% for GERM.

What is the main difference between GNOM and GERM?

GNOM tracks Solactive Genomics Index, while GERM tracks Prime Treatments, Testing and Advancements Index. They also come from different issuers: Global X and Amplify. Their fees differ too: 0.50% for GNOM and 0.68% for GERM.