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FMED vs. ALKS
Performance
Return for Risk
Drawdowns
Volatility
Dividends

Performance

FMED vs. ALKS - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Fidelity Disruptive Medicine ETF (FMED) and Alkermes plc (ALKS). The values are adjusted to include any dividend payments, if applicable.

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Returns By Period

In the year-to-date period, FMED achieves a -4.75% return, which is significantly lower than ALKS's 58.54% return.


FMED

1D
0.90%
1M
7.10%
YTD
-4.75%
6M
-6.17%
1Y
8.53%
3Y*
0.73%
5Y*
10Y*

ALKS

1D
0.18%
1M
18.36%
YTD
58.54%
6M
57.47%
1Y
48.71%
3Y*
11.28%
5Y*
12.07%
10Y*
0.70%
*Multi-year figures are annualized to reflect compound growth (CAGR)

FMED vs. ALKS - Yearly Performance Comparison


2026 (YTD)202520242023
FMED
Fidelity Disruptive Medicine ETF
-4.75%9.69%2.29%-3.59%
ALKS
Alkermes plc
58.54%-2.71%3.68%-10.89%

Correlation

The correlation between FMED and ALKS is 0.38, which is low. Their price movements are largely independent, making them effective diversification partners.


Correlation
Correlation (1Y)
Calculated over the trailing 1-year period

0.38

Correlation (3Y)
Calculated over the trailing 3-year period

0.39

Correlation (All Time)
Calculated using the full available price history since Jun 12, 2023

0.39

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Return for Risk

FMED vs. ALKS — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

FMED
FMED Risk / Return Rank: 1515
Overall Rank
FMED Sharpe Ratio Rank: 1616
Sharpe Ratio Rank
FMED Sortino Ratio Rank: 1616
Sortino Ratio Rank
FMED Omega Ratio Rank: 1515
Omega Ratio Rank
FMED Calmar Ratio Rank: 1414
Calmar Ratio Rank
FMED Martin Ratio Rank: 1414
Martin Ratio Rank

ALKS
ALKS Risk / Return Rank: 7676
Overall Rank
ALKS Sharpe Ratio Rank: 7777
Sharpe Ratio Rank
ALKS Sortino Ratio Rank: 7575
Sortino Ratio Rank
ALKS Omega Ratio Rank: 7373
Omega Ratio Rank
ALKS Calmar Ratio Rank: 7878
Calmar Ratio Rank
ALKS Martin Ratio Rank: 7676
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

FMED vs. ALKS - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Fidelity Disruptive Medicine ETF (FMED) and Alkermes plc (ALKS). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.


FMEDALKSDifference
Sharpe ratioReturn per unit of total volatility

-0.76

Sortino ratioReturn per unit of downside risk

-1.13

Omega ratioGain probability vs. loss probability

1.09

1.24

-0.15

Calmar ratioReturn relative to maximum drawdown

0.47

2.21

-1.74

Martin ratioReturn relative to average drawdown

1.03

5.11

-4.08

FMED vs. ALKS - Sharpe Ratio Comparison

The current FMED Sharpe Ratio is 0.44, which is lower than the ALKS Sharpe Ratio of 1.20. The chart below compares the historical Sharpe Ratios of FMED and ALKS, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.


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Drawdowns

FMED vs. ALKS - Drawdown Comparison

The maximum FMED drawdown since its inception was -21.84%, smaller than the maximum ALKS drawdown of -96.14%. Use the drawdown chart below to compare losses from any high point for FMED and ALKS.


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Drawdown Indicators


FMEDALKSDifference

Max Drawdown

Largest peak-to-trough decline

-21.84%

-96.14%

+74.30%

Max Drawdown (1Y)

Largest decline over 1 year

-18.33%

-22.20%

+3.87%

Max Drawdown (3Y)

Largest decline over 3 years

-21.84%

-31.58%

+9.74%

Max Drawdown (5Y)

Largest decline over 5 years

-33.18%

Max Drawdown (10Y)

Largest decline over 10 years

-80.58%

Current Drawdown

Current decline from peak

-10.64%

-54.76%

+44.12%

Average Drawdown

Average peak-to-trough decline

-7.09%

-67.23%

+60.14%

Ulcer Index

Depth and duration of drawdowns from previous peaks

8.27%

9.55%

-1.28%

Volatility

FMED vs. ALKS - Volatility Comparison

The current volatility for Fidelity Disruptive Medicine ETF (FMED) is 7.50%, while Alkermes plc (ALKS) has a volatility of 10.43%. This indicates that FMED experiences smaller price fluctuations and is considered to be less risky than ALKS based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


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Volatility by Period


FMEDALKSDifference

Volatility (1M)

Calculated over the trailing 1-month period

7.50%

10.43%

-2.93%

Volatility (6M)

Calculated over the trailing 6-month period

15.01%

30.28%

-15.27%

Volatility (1Y)

Calculated over the trailing 1-year period

19.37%

40.79%

-21.42%

Volatility (5Y)

Calculated over the trailing 5-year period, annualized

18.57%

37.33%

-18.76%

Volatility (10Y)

Calculated over the trailing 10-year period, annualized

18.57%

41.31%

-22.74%

Dividends

FMED vs. ALKS - Dividend Comparison

Neither FMED nor ALKS has paid dividends to shareholders.


PositionTTM20252024
ALKS
Alkermes plc
0.00%0.00%0.00%
FMED
Fidelity Disruptive Medicine ETF
0.00%0.00%0.46%

Frequently Asked Questions


FMED and ALKS have a correlation of 0.38, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

ALKS has higher volatility (10.43%) compared to FMED (7.50%). In terms of maximum drawdown, FMED dropped -21.84% vs ALKS's -96.14%.

ALKS currently has the higher Sharpe Ratio (1.20 vs 0.44), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.

Portfolio Optimizer

Find the right allocation for FMED and ALKS

Add both to a portfolio and optimize allocations for your target — whether that's maximizing returns, minimizing drawdowns, or balancing risk across holdings.

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