EPEM vs. MEDI

Last updated Jun 24, 2026

EPEM (Harbor Emerging Markets Equity ETF) and MEDI (Harbor Health Care ETF) are both exchange-traded funds - EPEM is a Emerging Markets Diversified fund actively managed by Harbor, while MEDI is a Health & Biotech Equities fund actively managed by Harbor. Both are actively managed. Over the past year, EPEM returned 47.71% vs 20.72% for MEDI. At a 0.21 correlation, their price movements are largely independent. EPEM charges 0.84%/yr vs 0.80%/yr for MEDI.

Performance

EPEM vs. MEDI - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Harbor Emerging Markets Equity ETF (EPEM) and Harbor Health Care ETF (MEDI). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, EPEM achieves a 24.23% return, which is significantly higher than MEDI's 0.41% return.

EPEM

• 1D: -4.50%
• 1M: 1.19%
• YTD: 24.23%
• 6M: 26.37%
• 1Y: 47.71%
• 3Y*: —
• 5Y*: —
• 10Y*: —

MEDI

• 1D: 1.41%
• 1M: 1.66%
• YTD: 0.41%
• 6M: -0.41%
• 1Y: 20.72%
• 3Y*: 13.92%
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

EPEM vs. MEDI - Yearly Performance Comparison

	2026 (YTD)	2025
EPEM Harbor Emerging Markets Equity ETF	24.23%	20.73%
MEDI Harbor Health Care ETF	0.41%	22.27%

Correlation

The correlation between EPEM and MEDI is 0.20, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.20
Correlation (All Time) Calculated using the full available price history since Jun 5, 2025	0.21

EPEM vs. MEDI - Sectors Allocation Comparison

Sectors	EPEM	MEDI
Technology	42.1%	-
Financial Services	22.1%	-
Consumer Cyclical	9.3%	-
Consumer Defensive	6.2%	-
Basic Materials	6.0%	-
Communication Services	5.6%	-
Energy	3.2%	-
Industrials	2.5%	-
Healthcare	1.8%	100.0%
Real Estate	1.2%	-
Utilities	-	-

Return for Risk

EPEM vs. MEDI — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

EPEM

EPEM Risk / Return Rank: 76
EPEM Sharpe Ratio Rank: 79
EPEM Sortino Ratio Rank: 70
EPEM Omega Ratio Rank: 79
EPEM Calmar Ratio Rank: 77
EPEM Martin Ratio Rank: 76

MEDI

MEDI Risk / Return Rank: 30
MEDI Sharpe Ratio Rank: 30
MEDI Sortino Ratio Rank: 32
MEDI Omega Ratio Rank: 28
MEDI Calmar Ratio Rank: 29
MEDI Martin Ratio Rank: 29

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

EPEM vs. MEDI - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Harbor Emerging Markets Equity ETF (EPEM) and Harbor Health Care ETF (MEDI). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	EPEM	MEDI	Difference
Sharpe ratio: Return per unit of total volatility	2.26	1.03	+1.23
Sortino ratio: Return per unit of downside risk	2.85	1.61	+1.23
Omega ratio: Gain probability vs. loss probability	1.42	1.18	+0.24
Calmar ratio: Return relative to maximum drawdown	3.61	1.36	+2.26
Martin ratio: Return relative to average drawdown	13.04	3.96	+9.09

EPEM vs. MEDI - Sharpe Ratio Comparison

The current EPEM Sharpe Ratio is 2.26, which is higher than the MEDI Sharpe Ratio of 1.03. The chart below compares the historical Sharpe Ratios of EPEM and MEDI, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

EPEM vs. MEDI - Drawdown Comparison

The maximum EPEM drawdown since its inception was -13.27%, smaller than the maximum MEDI drawdown of -19.24%. Use the drawdown chart below to compare losses from any high point for EPEM and MEDI.

Drawdown Indicators

	EPEM	MEDI	Difference
Max Drawdown Largest peak-to-trough decline	-13.27%	-19.24%	+5.97%
Max Drawdown (1Y) Largest decline over 1 year	-13.27%	-15.34%	+2.07%
Max Drawdown (3Y) Largest decline over 3 years	—	-19.24%	—
Current Drawdown Current decline from peak	-5.73%	-3.76%	-1.97%
Average Drawdown Average peak-to-trough decline	-2.08%	-4.30%	+2.22%
Ulcer Index Depth and duration of drawdowns from previous peaks	3.67%	5.25%	-1.58%

Volatility

EPEM vs. MEDI - Volatility Comparison

Harbor Emerging Markets Equity ETF (EPEM) has a higher volatility of 10.67% compared to Harbor Health Care ETF (MEDI) at 6.32%. This indicates that EPEM's price experiences larger fluctuations and is considered to be riskier than MEDI based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	EPEM	MEDI	Difference
Volatility (1M) Calculated over the trailing 1-month period	10.67%	6.32%	+4.35%
Volatility (6M) Calculated over the trailing 6-month period	18.89%	15.71%	+3.18%
Volatility (1Y) Calculated over the trailing 1-year period	21.19%	20.22%	+0.97%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	20.91%	18.68%	+2.23%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	20.91%	18.68%	+2.23%

EPEM vs. MEDI - Expense Ratio Comparison

EPEM has a 0.84% expense ratio, which is higher than MEDI's 0.80% expense ratio.

Dividends

EPEM vs. MEDI - Dividend Comparison

EPEM's dividend yield for the trailing twelve months is around 2.95%, more than MEDI's 0.28% yield.

Position	TTM	2025	2024	2023
EPEM Harbor Emerging Markets Equity ETF	2.95%	3.66%	0.00%	0.00%
MEDI Harbor Health Care ETF	0.28%	0.28%	0.54%	1.86%

Frequently Asked Questions

Can I hold both EPEM and MEDI in my portfolio?

EPEM and MEDI have a correlation of 0.20, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, EPEM or MEDI?

EPEM has higher volatility (10.67%) compared to MEDI (6.32%). In terms of maximum drawdown, EPEM dropped -13.27% vs MEDI's -19.24%.

Which ETF is better, EPEM or MEDI?

On 1-year performance, EPEM leads with 47.71% vs 20.72% for MEDI. On fees, MEDI is cheaper at 0.80% per year. On volatility, MEDI has been the lower-risk option at 6.32%. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF has performed better, EPEM or MEDI?

Over the 1-year period, EPEM has performed better with a 47.71% return vs 20.72%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.

Which ETF is cheaper, EPEM or MEDI?

MEDI is cheaper with a 0.80% expense ratio, compared with 0.84% for EPEM.

Which ETF pays a higher dividend yield, EPEM or MEDI?

EPEM has the higher dividend yield at 2.95%, compared with 0.28% for MEDI.

What is the main difference between EPEM and MEDI?

EPEM is categorized as Emerging Markets Diversified, while MEDI is Health & Biotech Equities. Their fees differ too: 0.84% for EPEM and 0.80% for MEDI.

Which has better risk-adjusted returns?

EPEM currently has the higher Sharpe Ratio (2.26 vs 1.03), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.