MEDI vs. MEDX

Last updated Apr 2, 2026

Compare and contrast key facts about Harbor Health Care ETF (MEDI) and Horizon Kinetics Medical ETF (MEDX).

MEDI and MEDX are both exchange-traded funds (ETFs), meaning they are traded on stock exchanges and can be bought and sold throughout the day. MEDI is an actively managed fund by Harbor. It was launched on Nov 16, 2022. MEDX is an actively managed fund by Horizon. It was launched on Sep 30, 1999.

Performance

MEDI vs. MEDX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Harbor Health Care ETF (MEDI) and Horizon Kinetics Medical ETF (MEDX). The values are adjusted to include any dividend payments, if applicable.

MEDI vs. MEDX - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023
MEDI Harbor Health Care ETF	-5.40%	27.11%	0.58%	22.22%
MEDX Horizon Kinetics Medical ETF	1.52%	28.62%	-4.68%	-6.22%

Returns By Period

In the year-to-date period, MEDI achieves a -5.40% return, which is significantly lower than MEDX's 1.52% return.

MEDI

• 1D: 1.48%
• 1M: -5.60%
• YTD: -5.40%
• 6M: 2.20%
• 1Y: 21.19%
• 3Y*: 14.13%
• 5Y*: —
• 10Y*: —

MEDX

• 1D: 1.19%
• 1M: -3.98%
• YTD: 1.52%
• 6M: 8.07%
• 1Y: 27.44%
• 3Y*: 6.83%
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

MEDI vs. MEDX - Expense Ratio Comparison

MEDI has a 0.80% expense ratio, which is lower than MEDX's 0.85% expense ratio.

MEDX

Horizon Kinetics Medical ETF

MEDI

Harbor Health Care ETF

Return for Risk

MEDI vs. MEDX — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

MEDI

MEDI Risk / Return Rank: 45
MEDI Sharpe Ratio Rank: 49
MEDI Sortino Ratio Rank: 51
MEDI Omega Ratio Rank: 43
MEDI Calmar Ratio Rank: 40
MEDI Martin Ratio Rank: 40

MEDX

MEDX Risk / Return Rank: 68
MEDX Sharpe Ratio Rank: 70
MEDX Sortino Ratio Rank: 71
MEDX Omega Ratio Rank: 61
MEDX Calmar Ratio Rank: 74
MEDX Martin Ratio Rank: 63

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

MEDI vs. MEDX - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Harbor Health Care ETF (MEDI) and Horizon Kinetics Medical ETF (MEDX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	MEDI	MEDX	Difference
Sharpe ratio Return per unit of total volatility	0.94	1.30	-0.35
Sortino ratio Return per unit of downside risk	1.43	1.87	-0.43
Omega ratio Gain probability vs. loss probability	1.18	1.24	-0.06
Calmar ratio Return relative to maximum drawdown	1.15	2.15	-1.00
Martin ratio Return relative to average drawdown	4.02	6.85	-2.83
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

MEDI vs. MEDX - Sharpe Ratio Comparison

The current MEDI Sharpe Ratio is 0.94, which is comparable to the MEDX Sharpe Ratio of 1.30. The chart below compares the historical Sharpe Ratios of MEDI and MEDX, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	MEDI	MEDX	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	0.94	1.30	-0.35
Sharpe Ratio (All Time) Calculated using the full available price history	0.76	0.30	+0.46

Correlation

The correlation between MEDI and MEDX is 0.73, which is considered to be high. That indicates a strong positive relationship between their price movements. Having highly-correlated positions in a portfolio may signal a lack of diversification, potentially leading to increased risk during market downturns.

Dividends

MEDI vs. MEDX - Dividend Comparison

MEDI's dividend yield for the trailing twelve months is around 0.29%, less than MEDX's 1.21% yield.

	TTM	2025	2024	2023
MEDI Harbor Health Care ETF	0.29%	0.28%	0.54%	1.86%
MEDX Horizon Kinetics Medical ETF	1.21%	1.23%	1.92%	4.94%

Drawdowns

MEDI vs. MEDX - Drawdown Comparison

The maximum MEDI drawdown since its inception was -19.24%, smaller than the maximum MEDX drawdown of -23.10%. Use the drawdown chart below to compare losses from any high point for MEDI and MEDX.

Drawdown Indicators

	MEDI	MEDX	Difference
Max Drawdown Largest peak-to-trough decline	-19.24%	-23.10%	+3.86%
Max Drawdown (1Y) Largest decline over 1 year	-15.34%	-10.86%	-4.48%
Current Drawdown Current decline from peak	-9.34%	-4.91%	-4.43%
Average Drawdown Average peak-to-trough decline	-4.09%	-6.72%	+2.63%
Ulcer Index Depth and duration of drawdowns from previous peaks	4.38%	3.40%	+0.98%

Volatility

MEDI vs. MEDX - Volatility Comparison

Harbor Health Care ETF (MEDI) has a higher volatility of 8.13% compared to Horizon Kinetics Medical ETF (MEDX) at 6.14%. This indicates that MEDI's price experiences larger fluctuations and is considered to be riskier than MEDX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	MEDI	MEDX	Difference
Volatility (1M) Calculated over the trailing 1-month period	8.13%	6.14%	+1.99%
Volatility (6M) Calculated over the trailing 6-month period	14.16%	13.42%	+0.74%
Volatility (1Y) Calculated over the trailing 1-year period	22.74%	21.48%	+1.26%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	18.48%	16.92%	+1.56%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	18.48%	16.92%	+1.56%