ELVN vs. INSM

Last updated Aug 1, 2026

ELVN (Enliven Therapeutics Inc.) and INSM (Insmed Incorporated) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. Over the past 5 years, ELVN returned 20.52%/yr vs 32.00%/yr for INSM. Their 0.26 correlation means their historical movements had little consistent relationship.

Performance

ELVN vs. INSM - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Enliven Therapeutics Inc. (ELVN) and Insmed Incorporated (INSM). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, ELVN achieves a 255.91% return, which is significantly higher than INSM's -43.35% return.

ELVN

• 1D: 1.59%
• 1M: 10.02%
• 6M: 107.22%
• YTD: 255.91%
• 1Y: 192.63%
• 3Y*: 42.23%
• 5Y*: 20.52%
• 10Y*: —
• ALL TIME*: -0.34%

INSM

• 1D: -2.85%
• 1M: -11.65%
• 6M: -37.15%
• YTD: -43.35%
• 1Y: -9.28%
• 3Y*: 64.55%
• 5Y*: 32.00%
• 10Y*: 24.10%
• ALL TIME*: -1.83%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison

Position	Avg. Volume Value (2W)	Avg. Volume Value (1M)	Avg. Volume Value (3M)
ELVN Enliven Therapeutics Inc.	$37.22M	$41.86M	$59.72M
INSM Insmed Incorporated	$231.83M	$255.55M	$410.72M

ELVN vs. INSM - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020
ELVN Enliven Therapeutics Inc.	255.91%	-31.56%	62.57%	-15.40%	81.78%	-89.80%	57.50%
INSM Insmed Incorporated	-43.35%	152.09%	122.78%	55.11%	-26.65%	-18.17%	56.66%

Correlation

The correlation between ELVN and INSM is 0.28, which is low. Their historical price movements had little consistent relationship.

	Correlation
Correlation (1Y) Focuses on recent behavior, but can change the most.	0.28
Correlation (3Y) Balances recent behavior with more history.	0.28
Correlation (5Y) Shows whether the relationship held over a longer period.	0.27
Correlation (All Time) Calculated using the full available price history since Mar 12, 2020	0.26

Fundamentals

Market Cap ELVN : $3.92B INSM : $21.37B
EPS ELVN : -$1.63 INSM : -$5.54
PB Ratio ELVN : 7.59 INSM : 30.14
Total Revenue (TTM) ELVN : $0.00 INSM : $819.56M
Gross Profit (TTM) ELVN : -$46.00K INSM : $668.55M
EBITDA (TTM) ELVN : -$110.65M INSM : -$1.14B

Return for Risk

ELVN vs. INSM — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

ELVN

ELVN Risk / Return Rank: 95
ELVN Sharpe Ratio Rank: 95
ELVN Sortino Ratio Rank: 95
ELVN Omega Ratio Rank: 93
ELVN Calmar Ratio Rank: 95
ELVN Martin Ratio Rank: 96

INSM

INSM Risk / Return Rank: 38
INSM Sharpe Ratio Rank: 38
INSM Sortino Ratio Rank: 37
INSM Omega Ratio Rank: 37
INSM Calmar Ratio Rank: 40
INSM Martin Ratio Rank: 40

The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

ELVN vs. INSM - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Enliven Therapeutics Inc. (ELVN) and Insmed Incorporated (INSM). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	ELVN	INSM	Difference
Sharpe ratio: Return per unit of total volatility	2.40	-0.15	+2.56
Sortino ratio: Return per unit of downside risk	3.52	0.15	+3.37
Omega ratio: Gain probability vs. loss probability	1.42	1.02	+0.39
Calmar ratio: Return relative to maximum drawdown	5.23	-0.14	+5.37
Martin ratio: Return relative to average drawdown	15.54	-0.27	+15.81

ELVN vs. INSM - Sharpe Ratio Comparison

The current ELVN Sharpe Ratio is 2.40, which is higher than the INSM Sharpe Ratio of -0.15. The chart below compares the historical Sharpe Ratios of ELVN and INSM, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

ELVN vs. INSM - Drawdown Comparison

The maximum ELVN drawdown since its inception was -98.20%, roughly equal to the maximum INSM drawdown of -98.65%. Use the drawdown chart below to compare losses from any high point for ELVN and INSM.

Drawdown Indicators

	ELVN	INSM	Difference
Max Drawdown Largest peak-to-trough decline	-98.20%	-98.65%	+0.45%
Max Drawdown (1Y) Largest decline over 1 year	-36.84%	-56.54%	+19.70%
Max Drawdown (3Y) Largest decline over 3 years	-49.54%	-56.54%	+7.00%
Max Drawdown (5Y) Largest decline over 5 years	-83.22%	-56.54%	-26.68%
Max Drawdown (10Y) Largest decline over 10 years	—	-64.84%	—
Current Drawdown Current decline from peak	-75.03%	-53.36%	-21.67%
Average Drawdown Average peak-to-trough decline	-84.02%	-85.89%	+1.87%
Ulcer Index Depth and duration of drawdowns from previous peaks	12.37%	29.74%	-17.37%

Volatility

ELVN vs. INSM - Volatility Comparison

Enliven Therapeutics Inc. (ELVN) has a higher volatility of 11.07% compared to Insmed Incorporated (INSM) at 10.10%. This indicates that ELVN's price experiences larger fluctuations and is considered to be riskier than INSM based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	ELVN	INSM	Difference
Volatility (1M) Calculated over the trailing 1-month period	11.07%	10.10%	+0.97%
Volatility (6M) Calculated over the trailing 6-month period	43.79%	42.65%	+1.14%
Volatility (1Y) Calculated over the trailing 1-year period	80.17%	52.55%	+27.62%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	85.79%	72.76%	+13.03%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	87.45%	78.39%	+9.06%

Dividends

ELVN vs. INSM - Dividend Comparison

Neither ELVN nor INSM has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both ELVN and INSM in my portfolio?

ELVN and INSM have a correlation of 0.28, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, ELVN or INSM?

ELVN has higher volatility (11.07%) compared to INSM (10.10%). In terms of maximum drawdown, ELVN dropped -98.20% vs INSM's -98.65%.

Which has better risk-adjusted returns?

ELVN currently has the higher Sharpe Ratio (2.40 vs -0.15), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.