DNA vs. VTI
DNA (Ginkgo Bioworks Holdings, Inc.) is a stock, while VTI (Vanguard Total Stock Market ETF) is Large Cap Blend Equities fund tracking the CRSP US Total Market Index. Over the past 5 years, DNA returned -53.86%/yr vs 12.32%/yr for VTI. At a 0.48 correlation, their price movements are largely independent.
Performance
DNA vs. VTI - Performance Comparison
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Returns By Period
In the year-to-date period, DNA achieves a -0.24% return, which is significantly lower than VTI's 11.20% return.
DNA
- 1D
- -7.89%
- 1M
- 0.97%
- 6M
- -13.47%
- YTD
- -0.24%
- 1Y
- -13.65%
- 3Y*
- -54.36%
- 5Y*
- -53.86%
- 10Y*
- —
VTI
- 1D
- -0.49%
- 1M
- 0.34%
- 6M
- 8.99%
- YTD
- 11.20%
- 1Y
- 22.02%
- 3Y*
- 19.69%
- 5Y*
- 12.32%
- 10Y*
- 14.66%
DNA vs. VTI - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | |
|---|---|---|---|---|---|---|
DNA Ginkgo Bioworks Holdings, Inc. | -0.24% | -15.38% | -85.47% | 0.00% | -79.66% | -21.68% |
VTI Vanguard Total Stock Market ETF | 11.20% | 17.10% | 23.81% | 26.05% | -19.52% | 12.28% |
Correlation
The correlation between DNA and VTI is 0.43, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.43 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.47 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.49 |
Correlation (All Time) Calculated using the full available price history since Apr 19, 2021 | 0.48 |
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Return for Risk
DNA vs. VTI — Risk / Return Rank
DNA
VTI
DNA vs. VTI - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Ginkgo Bioworks Holdings, Inc. (DNA) and Vanguard Total Stock Market ETF (VTI). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| DNA | VTI | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -1.87 | ||
| Sortino ratioReturn per unit of downside risk | -1.91 | ||
| Omega ratioGain probability vs. loss probability | 1.06 | 1.31 | -0.25 |
| Calmar ratioReturn relative to maximum drawdown | -0.21 | 2.48 | -2.69 |
| Martin ratioReturn relative to average drawdown | -0.33 | 10.85 | -11.19 |
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Drawdowns
DNA vs. VTI - Drawdown Comparison
The maximum DNA drawdown since its inception was -99.10%, which is greater than VTI's maximum drawdown of -55.45%. Use the drawdown chart below to compare losses from any high point for DNA and VTI.
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Drawdown Indicators
| DNA | VTI | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -99.10% | -55.45% | -43.65% |
Max Drawdown (1Y)Largest decline over 1 year | -66.05% | -8.92% | -57.13% |
Max Drawdown (3Y)Largest decline over 3 years | -94.72% | -19.30% | -75.42% |
Max Drawdown (5Y)Largest decline over 5 years | -99.10% | -25.36% | -73.74% |
Max Drawdown (10Y)Largest decline over 10 years | — | -35.00% | — |
Current DrawdownCurrent decline from peak | -98.61% | -0.73% | -97.88% |
Average DrawdownAverage peak-to-trough decline | -80.19% | -8.00% | -72.19% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 40.85% | 2.03% | +38.82% |
Volatility
DNA vs. VTI - Volatility Comparison
Ginkgo Bioworks Holdings, Inc. (DNA) has a higher volatility of 22.36% compared to Vanguard Total Stock Market ETF (VTI) at 3.38%. This indicates that DNA's price experiences larger fluctuations and is considered to be riskier than VTI based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| DNA | VTI | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 22.36% | 3.38% | +18.98% |
Volatility (6M)Calculated over the trailing 6-month period | 72.01% | 10.13% | +61.88% |
Volatility (1Y)Calculated over the trailing 1-year period | 95.74% | 12.82% | +82.92% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 98.37% | 17.51% | +80.86% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 96.02% | 18.28% | +77.74% |
Dividends
DNA vs. VTI - Dividend Comparison
DNA has not paid dividends to shareholders, while VTI's dividend yield for the trailing twelve months is around 1.05%.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA Ginkgo Bioworks Holdings, Inc. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
VTI Vanguard Total Stock Market ETF | 1.05% | 1.12% | 1.27% | 1.44% | 1.66% | 1.21% | 1.42% | 1.78% | 2.04% | 1.71% | 1.92% | 1.98% |
Frequently Asked Questions
DNA and VTI have a correlation of 0.43, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
DNA has higher volatility (22.36%) compared to VTI (3.38%). In terms of maximum drawdown, DNA dropped -99.10% vs VTI's -55.45%.
VTI currently has the higher Sharpe Ratio (1.72 vs -0.14), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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