DNA vs. VTI
DNA (Ginkgo Bioworks Holdings, Inc.) is a stock, while VTI (Vanguard Total Stock Market ETF) is Large Cap Blend Equities fund tracking the CRSP US Total Market Index. Over the past 5 years, DNA returned -52.38%/yr vs 11.81%/yr for VTI. At a 0.49 correlation, their price movements are largely independent.
Performance
DNA vs. VTI - Performance Comparison
Loading charts...
Returns By Period
In the year-to-date period, DNA achieves a 17.09% return, which is significantly higher than VTI's 8.80% return.
DNA
- 1D
- 9.82%
- 1M
- 15.70%
- YTD
- 17.09%
- 6M
- 9.20%
- 1Y
- 5.88%
- 3Y*
- -47.70%
- 5Y*
- -52.38%
- 10Y*
- —
VTI
- 1D
- -0.01%
- 1M
- -0.86%
- YTD
- 8.80%
- 6M
- 7.33%
- 1Y
- 22.77%
- 3Y*
- 20.62%
- 5Y*
- 11.81%
- 10Y*
- 15.14%
DNA vs. VTI - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | |
|---|---|---|---|---|---|---|
DNA Ginkgo Bioworks Holdings, Inc. | 17.09% | -15.38% | -85.47% | 0.00% | -79.66% | -21.68% |
VTI Vanguard Total Stock Market ETF | 8.80% | 17.10% | 23.81% | 26.05% | -19.52% | 12.28% |
Correlation
The correlation between DNA and VTI is 0.46, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.46 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.48 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.49 |
Correlation (All Time) Calculated using the full available price history since Apr 19, 2021 | 0.49 |
Compare stocks, funds, or ETFs
Search for stocks, ETFs, and funds for a quick comparison or use the comparison tool for more options.
Return for Risk
DNA vs. VTI — Risk / Return Rank
DNA
VTI
DNA vs. VTI - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Ginkgo Bioworks Holdings, Inc. (DNA) and Vanguard Total Stock Market ETF (VTI). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| DNA | VTI | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -1.73 | ||
| Sortino ratioReturn per unit of downside risk | -1.65 | ||
| Omega ratioGain probability vs. loss probability | 1.10 | 1.32 | -0.22 |
| Calmar ratioReturn relative to maximum drawdown | 0.09 | 2.56 | -2.47 |
| Martin ratioReturn relative to average drawdown | 0.15 | 11.37 | -11.22 |
Loading charts...
Drawdowns
DNA vs. VTI - Drawdown Comparison
The maximum DNA drawdown since its inception was -99.10%, which is greater than VTI's maximum drawdown of -55.45%. Use the drawdown chart below to compare losses from any high point for DNA and VTI.
Loading charts...
Drawdown Indicators
| DNA | VTI | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -99.10% | -55.45% | -43.65% |
Max Drawdown (1Y)Largest decline over 1 year | -66.05% | -8.92% | -57.13% |
Max Drawdown (3Y)Largest decline over 3 years | -94.72% | -19.30% | -75.42% |
Max Drawdown (5Y)Largest decline over 5 years | -99.10% | -25.36% | -73.74% |
Max Drawdown (10Y)Largest decline over 10 years | — | -35.00% | — |
Current DrawdownCurrent decline from peak | -98.37% | -2.86% | -95.51% |
Average DrawdownAverage peak-to-trough decline | -79.98% | -8.01% | -71.97% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 39.81% | 2.01% | +37.80% |
Volatility
DNA vs. VTI - Volatility Comparison
Ginkgo Bioworks Holdings, Inc. (DNA) has a higher volatility of 21.26% compared to Vanguard Total Stock Market ETF (VTI) at 4.93%. This indicates that DNA's price experiences larger fluctuations and is considered to be riskier than VTI based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
Loading charts...
Volatility by Period
| DNA | VTI | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 21.26% | 4.93% | +16.33% |
Volatility (6M)Calculated over the trailing 6-month period | 71.35% | 10.02% | +61.33% |
Volatility (1Y)Calculated over the trailing 1-year period | 98.09% | 12.80% | +85.29% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 98.06% | 17.50% | +80.56% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 96.27% | 18.31% | +77.96% |
Dividends
DNA vs. VTI - Dividend Comparison
DNA has not paid dividends to shareholders, while VTI's dividend yield for the trailing twelve months is around 1.04%.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA Ginkgo Bioworks Holdings, Inc. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
VTI Vanguard Total Stock Market ETF | 1.04% | 1.12% | 1.27% | 1.44% | 1.66% | 1.21% | 1.42% | 1.78% | 2.04% | 1.71% | 1.92% | 1.98% |
Frequently Asked Questions
DNA and VTI have a correlation of 0.46, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
DNA has higher volatility (21.26%) compared to VTI (4.93%). In terms of maximum drawdown, DNA dropped -99.10% vs VTI's -55.45%.
VTI currently has the higher Sharpe Ratio (1.79 vs 0.06), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
Find the right allocation for DNA and VTI
Add both to a portfolio and optimize allocations for your target — whether that's maximizing returns, minimizing drawdowns, or balancing risk across holdings.
Open Portfolio Optimizer