COSM vs. AYTU

Last updated Apr 1, 2026

Compare and contrast key facts about Cosmos Health Inc. (COSM) and Aytu BioPharma, Inc. (AYTU).

Performance

COSM vs. AYTU - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Cosmos Health Inc. (COSM) and Aytu BioPharma, Inc. (AYTU). The values are adjusted to include any dividend payments, if applicable.

COSM vs. AYTU - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
COSM Cosmos Health Inc.	-36.31%	-25.56%	-52.55%	-69.08%	-94.59%	-33.92%	131.82%	-45.00%	-60.78%	1,086.05%
AYTU Aytu BioPharma, Inc.	5.00%	52.94%	-40.14%	-24.87%	-86.00%	-77.42%	-38.35%	22.41%	-98.22%	-88.85%

Fundamentals

Market Cap COSM : $9.71M AYTU : $27.40M
EPS COSM : -$0.62 AYTU : -$2.02
PS Ratio COSM : 0.16 AYTU : 0.53
PB Ratio COSM : 0.42 AYTU : 1.93
Total Revenue (TTM) COSM : $59.79M AYTU : $62.64M
Gross Profit (TTM) COSM : $6.82M AYTU : $41.34M
EBITDA (TTM) COSM : -$14.92M AYTU : -$17.24M

Returns By Period

In the year-to-date period, COSM achieves a -36.31% return, which is significantly lower than AYTU's 5.00% return.

COSM

• 1D: -2.76%
• 1M: -19.35%
• YTD: -36.31%
• 6M: -71.42%
• 1Y: -27.25%
• 3Y*: -55.25%
• 5Y*: -69.74%
• 10Y*: -33.88%

AYTU

• 1D: 3.61%
• 1M: 6.23%
• YTD: 5.00%
• 6M: 45.21%
• 1Y: 127.50%
• 3Y*: 6.82%
• 5Y*: -55.20%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

COSM vs. AYTU — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

COSM

COSM Risk / Return Rank: 32
COSM Sharpe Ratio Rank: 28
COSM Sortino Ratio Rank: 36
COSM Omega Ratio Rank: 35
COSM Calmar Ratio Rank: 29
COSM Martin Ratio Rank: 29

AYTU

AYTU Risk / Return Rank: 86
AYTU Sharpe Ratio Rank: 76
AYTU Sortino Ratio Rank: 92
AYTU Omega Ratio Rank: 90
AYTU Calmar Ratio Rank: 85
AYTU Martin Ratio Rank: 85

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

COSM vs. AYTU - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Cosmos Health Inc. (COSM) and Aytu BioPharma, Inc. (AYTU). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	COSM	AYTU	Difference
Sharpe ratio Return per unit of total volatility	-0.27	1.09	-1.36
Sortino ratio Return per unit of downside risk	0.27	3.01	-2.73
Omega ratio Gain probability vs. loss probability	1.03	1.39	-0.36
Calmar ratio Return relative to maximum drawdown	-0.40	2.96	-3.35
Martin ratio Return relative to average drawdown	-0.71	7.81	-8.53
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

COSM vs. AYTU - Sharpe Ratio Comparison

The current COSM Sharpe Ratio is -0.27, which is lower than the AYTU Sharpe Ratio of 1.09. The chart below compares the historical Sharpe Ratios of COSM and AYTU, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	COSM	AYTU	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.27	1.09	-1.36
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.44	-0.65	+0.20
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	-0.09	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.04	-0.36	+0.31

Correlation

The correlation between COSM and AYTU is 0.09, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

COSM vs. AYTU - Dividend Comparison

Neither COSM nor AYTU has paid dividends to shareholders.

Tickers have no history of dividend payments

Drawdowns

COSM vs. AYTU - Drawdown Comparison

The maximum COSM drawdown since its inception was -99.90%, roughly equal to the maximum AYTU drawdown of -100.00%. Use the drawdown chart below to compare losses from any high point for COSM and AYTU.

Drawdown Indicators

	COSM	AYTU	Difference
Max Drawdown Largest peak-to-trough decline	-99.90%	-100.00%	+0.10%
Max Drawdown (1Y) Largest decline over 1 year	-74.82%	-42.47%	-32.35%
Max Drawdown (5Y) Largest decline over 5 years	-99.84%	-99.34%	-0.50%
Max Drawdown (10Y) Largest decline over 10 years	-99.90%	—	—
Current Drawdown Current decline from peak	-99.90%	-100.00%	+0.10%
Average Drawdown Average peak-to-trough decline	-63.96%	-95.05%	+31.09%
Ulcer Index Depth and duration of drawdowns from previous peaks	41.57%	16.07%	+25.50%

Volatility

COSM vs. AYTU - Volatility Comparison

Cosmos Health Inc. (COSM) has a higher volatility of 18.59% compared to Aytu BioPharma, Inc. (AYTU) at 9.71%. This indicates that COSM's price experiences larger fluctuations and is considered to be riskier than AYTU based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	COSM	AYTU	Difference
Volatility (1M) Calculated over the trailing 1-month period	18.59%	9.71%	+8.88%
Volatility (6M) Calculated over the trailing 6-month period	61.03%	39.38%	+21.65%
Volatility (1Y) Calculated over the trailing 1-year period	100.48%	117.87%	-17.39%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	158.27%	85.83%	+72.44%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	373.54%	190.04%	+183.50%

Financials

COSM vs. AYTU - Profitability Comparison

The chart below illustrates the profitability comparison between Cosmos Health Inc. and Aytu BioPharma, Inc. over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

COSM - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Apr 2026, Cosmos Health Inc. reported a gross profit of 2.60M and revenue of 17.11M. Therefore, the gross margin over that period was 15.2%.

AYTU - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Apr 2026, Aytu BioPharma, Inc. reported a gross profit of 9.10M and revenue of 15.17M. Therefore, the gross margin over that period was 60.0%.

COSM - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Apr 2026, Cosmos Health Inc. reported an operating income of -1.82M and revenue of 17.11M, resulting in an operating margin of -10.6%.

AYTU - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Apr 2026, Aytu BioPharma, Inc. reported an operating income of -1.97M and revenue of 15.17M, resulting in an operating margin of -13.0%.

COSM - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Apr 2026, Cosmos Health Inc. reported a net income of -5.35M and revenue of 17.11M, resulting in a net margin of -31.3%.

AYTU - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Apr 2026, Aytu BioPharma, Inc. reported a net income of -10.58M and revenue of 15.17M, resulting in a net margin of -69.8%.