COSM vs. AYTU

Last updated Jun 3, 2026

COSM (Cosmos Health Inc.) and AYTU (Aytu BioPharma, Inc.) are both stocks. Both are in the Healthcare sector — COSM in Medical Distribution, AYTU in Drug Manufacturers - Specialty & Generic. Over the past 5 years, COSM returned -70.07%/yr vs -54.20%/yr for AYTU. At a 0.09 correlation, their price movements are largely independent.

Performance

COSM vs. AYTU - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Cosmos Health Inc. (COSM) and Aytu BioPharma, Inc. (AYTU). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, COSM achieves a -47.59% return, which is significantly lower than AYTU's -19.23% return.

COSM

• 1D: 3.33%
• 1M: -31.24%
• YTD: -47.59%
• 6M: -52.58%
• 1Y: -43.14%
• 3Y*: -57.75%
• 5Y*: -70.07%
• 10Y*: -33.14%

AYTU

• 1D: -2.33%
• 1M: -19.54%
• YTD: -19.23%
• 6M: 2.44%
• 1Y: 17.98%
• 3Y*: 4.89%
• 5Y*: -54.20%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

COSM vs. AYTU - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
COSM Cosmos Health Inc.	-47.59%	-25.56%	-52.55%	-69.08%	-94.59%	-33.92%	131.82%	-45.00%	-60.78%	1,086.05%
AYTU Aytu BioPharma, Inc.	-19.23%	52.94%	-40.14%	-24.87%	-86.00%	-77.42%	-38.35%	22.41%	-98.22%	-88.85%

Correlation

The correlation between COSM and AYTU is 0.16, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.16
Correlation (3Y) Calculated over the trailing 3-year period	0.12
Correlation (5Y) Calculated over the trailing 5-year period	0.12
Correlation (All Time) Calculated using the full available price history since Feb 2, 2017	0.09

Fundamentals

EPS COSM : -$0.62 AYTU : -$2.91
PS Ratio COSM : 0.13 AYTU : 0.43
Total Revenue (TTM) COSM : $59.79M AYTU : $56.60M
Gross Profit (TTM) COSM : $6.82M AYTU : $36.14M
EBITDA (TTM) COSM : -$14.92M AYTU : -$27.34M

Return for Risk

COSM vs. AYTU — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

COSM

COSM Risk / Return Rank: 24
COSM Sharpe Ratio Rank: 22
COSM Sortino Ratio Rank: 26
COSM Omega Ratio Rank: 27
COSM Calmar Ratio Rank: 22
COSM Martin Ratio Rank: 25

AYTU

AYTU Risk / Return Rank: 52
AYTU Sharpe Ratio Rank: 50
AYTU Sortino Ratio Rank: 51
AYTU Omega Ratio Rank: 51
AYTU Calmar Ratio Rank: 52
AYTU Martin Ratio Rank: 53

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

COSM vs. AYTU - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Cosmos Health Inc. (COSM) and Aytu BioPharma, Inc. (AYTU). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	COSM	AYTU	Difference
Sharpe ratio Return per unit of total volatility	-0.44	0.27	-0.71
Sortino ratio Return per unit of downside risk	-0.14	0.92	-1.06
Omega ratio Gain probability vs. loss probability	0.98	1.12	-0.13
Calmar ratio Return relative to maximum drawdown	-0.51	0.51	-1.02
Martin ratio Return relative to average drawdown	-0.80	1.23	-2.03
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

COSM vs. AYTU - Sharpe Ratio Comparison

The current COSM Sharpe Ratio is -0.44, which is lower than the AYTU Sharpe Ratio of 0.27. The chart below compares the historical Sharpe Ratios of COSM and AYTU, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	COSM	AYTU	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.44	0.27	-0.71
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.45	-0.64	+0.19
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	-0.09	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.05	-0.36	+0.31

Drawdowns

COSM vs. AYTU - Drawdown Comparison

The maximum COSM drawdown since its inception was -99.92%, roughly equal to the maximum AYTU drawdown of -100.00%. Use the drawdown chart below to compare losses from any high point for COSM and AYTU.

Drawdown Indicators

	COSM	AYTU	Difference
Max Drawdown Largest peak-to-trough decline	-99.92%	-100.00%	+0.08%
Max Drawdown (1Y) Largest decline over 1 year	-80.24%	-35.47%	-44.77%
Max Drawdown (3Y) Largest decline over 3 years	-93.53%	-70.24%	-23.29%
Max Drawdown (5Y) Largest decline over 5 years	-99.87%	-99.12%	-0.75%
Max Drawdown (10Y) Largest decline over 10 years	-99.92%	—	—
Current Drawdown Current decline from peak	-99.92%	-100.00%	+0.08%
Average Drawdown Average peak-to-trough decline	-64.42%	-95.14%	+30.72%
Ulcer Index Depth and duration of drawdowns from previous peaks	51.40%	14.66%	+36.74%

Volatility

COSM vs. AYTU - Volatility Comparison

Cosmos Health Inc. (COSM) has a higher volatility of 16.79% compared to Aytu BioPharma, Inc. (AYTU) at 12.52%. This indicates that COSM's price experiences larger fluctuations and is considered to be riskier than AYTU based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	COSM	AYTU	Difference
Volatility (1M) Calculated over the trailing 1-month period	16.79%	12.52%	+4.27%
Volatility (6M) Calculated over the trailing 6-month period	57.97%	33.97%	+24.00%
Volatility (1Y) Calculated over the trailing 1-year period	99.06%	66.08%	+32.98%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	157.81%	85.63%	+72.18%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	373.25%	188.35%	+184.90%

Dividends

COSM vs. AYTU - Dividend Comparison

Neither COSM nor AYTU has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both COSM and AYTU in my portfolio?

COSM and AYTU have a correlation of 0.16, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, COSM or AYTU?

COSM has higher volatility (16.79%) compared to AYTU (12.52%). In terms of maximum drawdown, COSM dropped -99.92% vs AYTU's -100.00%.

Which has better risk-adjusted returns?

AYTU currently has the higher Sharpe Ratio (0.27 vs -0.44), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.