COSM vs. ANRO

Last updated Apr 1, 2026

Compare and contrast key facts about Cosmos Health Inc. (COSM) and Alto Neuroscience, Inc (ANRO).

Performance

COSM vs. ANRO - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Cosmos Health Inc. (COSM) and Alto Neuroscience, Inc (ANRO). The values are adjusted to include any dividend payments, if applicable.

COSM vs. ANRO - Yearly Performance Comparison

	2026 (YTD)	2025	2024
COSM Cosmos Health Inc.	-36.31%	-25.56%	-37.77%
ANRO Alto Neuroscience, Inc	26.29%	320.80%	-79.57%

Fundamentals

Market Cap COSM : $9.71M ANRO : $717.64M
EPS COSM : -$0.62 ANRO : -$2.20
PB Ratio COSM : 0.42 ANRO : 4.75
Total Revenue (TTM) COSM : $59.79M ANRO : $0.00
Gross Profit (TTM) COSM : $6.82M ANRO : -$421.00K
EBITDA (TTM) COSM : -$14.92M ANRO : -$61.63M

Returns By Period

In the year-to-date period, COSM achieves a -36.31% return, which is significantly lower than ANRO's 26.29% return.

COSM

• 1D: -2.76%
• 1M: -19.35%
• YTD: -36.31%
• 6M: -71.42%
• 1Y: -27.25%
• 3Y*: -55.25%
• 5Y*: -69.74%
• 10Y*: -33.88%

ANRO

• 1D: 12.51%
• 1M: 14.17%
• YTD: 26.29%
• 6M: 459.20%
• 1Y: 940.74%
• 3Y*: —
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

COSM vs. ANRO — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

COSM

COSM Risk / Return Rank: 32
COSM Sharpe Ratio Rank: 28
COSM Sortino Ratio Rank: 36
COSM Omega Ratio Rank: 35
COSM Calmar Ratio Rank: 29
COSM Martin Ratio Rank: 29

ANRO

ANRO Risk / Return Rank: 99
ANRO Sharpe Ratio Rank: 100
ANRO Sortino Ratio Rank: 99
ANRO Omega Ratio Rank: 98
ANRO Calmar Ratio Rank: 100
ANRO Martin Ratio Rank: 100

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

COSM vs. ANRO - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Cosmos Health Inc. (COSM) and Alto Neuroscience, Inc (ANRO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	COSM	ANRO	Difference
Sharpe ratio Return per unit of total volatility	-0.27	7.25	-7.52
Sortino ratio Return per unit of downside risk	0.27	5.65	-5.38
Omega ratio Gain probability vs. loss probability	1.03	1.71	-0.68
Calmar ratio Return relative to maximum drawdown	-0.40	30.09	-30.48
Martin ratio Return relative to average drawdown	-0.71	72.94	-73.66
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

COSM vs. ANRO - Sharpe Ratio Comparison

The current COSM Sharpe Ratio is -0.27, which is lower than the ANRO Sharpe Ratio of 7.25. The chart below compares the historical Sharpe Ratios of COSM and ANRO, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	COSM	ANRO	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.27	7.25	-7.52
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.44	—	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	-0.09	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.04	0.03	-0.08

Correlation

The correlation between COSM and ANRO is 0.16, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

COSM vs. ANRO - Dividend Comparison

Neither COSM nor ANRO has paid dividends to shareholders.

Tickers have no history of dividend payments

Drawdowns

COSM vs. ANRO - Drawdown Comparison

The maximum COSM drawdown since its inception was -99.90%, which is greater than ANRO's maximum drawdown of -91.74%. Use the drawdown chart below to compare losses from any high point for COSM and ANRO.

Drawdown Indicators

	COSM	ANRO	Difference
Max Drawdown Largest peak-to-trough decline	-99.90%	-91.74%	-8.16%
Max Drawdown (1Y) Largest decline over 1 year	-74.82%	-29.59%	-45.23%
Max Drawdown (5Y) Largest decline over 5 years	-99.84%	—	—
Max Drawdown (10Y) Largest decline over 10 years	-99.90%	—	—
Current Drawdown Current decline from peak	-99.90%	-7.45%	-92.45%
Average Drawdown Average peak-to-trough decline	-63.96%	-56.91%	-7.05%
Ulcer Index Depth and duration of drawdowns from previous peaks	41.57%	12.21%	+29.36%

Volatility

COSM vs. ANRO - Volatility Comparison

The current volatility for Cosmos Health Inc. (COSM) is 18.59%, while Alto Neuroscience, Inc (ANRO) has a volatility of 24.93%. This indicates that COSM experiences smaller price fluctuations and is considered to be less risky than ANRO based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	COSM	ANRO	Difference
Volatility (1M) Calculated over the trailing 1-month period	18.59%	24.93%	-6.34%
Volatility (6M) Calculated over the trailing 6-month period	61.03%	98.02%	-36.99%
Volatility (1Y) Calculated over the trailing 1-year period	100.48%	131.26%	-30.78%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	158.27%	118.76%	+39.51%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	373.54%	118.76%	+254.78%

Financials