ANRO vs. PSNL
ANRO (Alto Neuroscience, Inc) and PSNL (Personalis, Inc.) are both stocks. Both are in the Healthcare sector — ANRO in Biotechnology, PSNL in Diagnostics & Research. Over the past year, ANRO returned 978.08% vs 136.11% for PSNL. At a 0.21 correlation, their price movements are largely independent.
Performance
ANRO vs. PSNL - Performance Comparison
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Returns By Period
In the year-to-date period, ANRO achieves a 57.47% return, which is significantly lower than PSNL's 88.94% return.
ANRO
- 1D
- 5.85%
- 1M
- 30.55%
- 6M
- 65.47%
- YTD
- 57.47%
- 1Y
- 978.08%
- 3Y*
- —
- 5Y*
- —
- 10Y*
- —
PSNL
- 1D
- 6.89%
- 1M
- 56.83%
- 6M
- 75.50%
- YTD
- 88.94%
- 1Y
- 136.11%
- 3Y*
- 95.27%
- 5Y*
- -6.66%
- 10Y*
- —
ANRO vs. PSNL - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | |
|---|---|---|---|
ANRO Alto Neuroscience, Inc | 57.47% | 320.80% | -80.77% |
PSNL Personalis, Inc. | 88.94% | 37.72% | 348.06% |
Correlation
The correlation between ANRO and PSNL is 0.22, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.22 |
Correlation (All Time) Calculated using the full available price history since Feb 2, 2024 | 0.21 |
Fundamentals
ANRO:
$983.68M
PSNL:
$1.34B
ANRO:
-$2.43
PSNL:
-$1.01
ANRO:
3.79
PSNL:
6.15
ANRO:
$0.00
PSNL:
$49.04M
ANRO:
-$421.00K
PSNL:
-$6.62M
ANRO:
-$74.36M
PSNL:
-$90.09M
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Return for Risk
ANRO vs. PSNL — Risk / Return Rank
ANRO
PSNL
ANRO vs. PSNL - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Alto Neuroscience, Inc (ANRO) and Personalis, Inc. (PSNL). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| ANRO | PSNL | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +6.23 | ||
| Sortino ratioReturn per unit of downside risk | +3.61 | ||
| Omega ratioGain probability vs. loss probability | 1.73 | 1.28 | +0.45 |
| Calmar ratioReturn relative to maximum drawdown | 28.90 | 2.48 | +26.42 |
| Martin ratioReturn relative to average drawdown | 75.56 | 5.36 | +70.21 |
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Drawdowns
ANRO vs. PSNL - Drawdown Comparison
The maximum ANRO drawdown since its inception was -91.82%, smaller than the maximum PSNL drawdown of -98.18%. Use the drawdown chart below to compare losses from any high point for ANRO and PSNL.
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Drawdown Indicators
| ANRO | PSNL | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -91.82% | -98.18% | +6.36% |
Max Drawdown (1Y)Largest decline over 1 year | -34.20% | -55.20% | +21.00% |
Max Drawdown (3Y)Largest decline over 3 years | — | -60.59% | — |
Max Drawdown (5Y)Largest decline over 5 years | — | -95.90% | — |
Current DrawdownCurrent decline from peak | -0.14% | -70.52% | +70.38% |
Average DrawdownAverage peak-to-trough decline | -52.23% | -75.71% | +23.48% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 13.05% | 25.52% | -12.47% |
Volatility
ANRO vs. PSNL - Volatility Comparison
The current volatility for Alto Neuroscience, Inc (ANRO) is 19.06%, while Personalis, Inc. (PSNL) has a volatility of 20.79%. This indicates that ANRO experiences smaller price fluctuations and is considered to be less risky than PSNL based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| ANRO | PSNL | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 19.06% | 20.79% | -1.73% |
Volatility (6M)Calculated over the trailing 6-month period | 54.73% | 63.63% | -8.90% |
Volatility (1Y)Calculated over the trailing 1-year period | 128.62% | 93.08% | +35.54% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 114.57% | 103.51% | +11.06% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 114.57% | 98.00% | +16.57% |
Dividends
ANRO vs. PSNL - Dividend Comparison
Neither ANRO nor PSNL has paid dividends to shareholders.
Financials
ANRO vs. PSNL - Financials Comparison
This section allows you to compare key financial metrics between Alto Neuroscience, Inc and Personalis, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
Frequently Asked Questions
ANRO and PSNL have a correlation of 0.22, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
PSNL has higher volatility (20.79%) compared to ANRO (19.06%). In terms of maximum drawdown, ANRO dropped -91.82% vs PSNL's -98.18%.
ANRO currently has the higher Sharpe Ratio (7.70 vs 1.47), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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