- ISIN
- US02157Q1094
- Sector
- Healthcare
- Industry
- Biotechnology
- IPO Date
- Feb 2, 2024
Highlights
- Market Cap
- $754.24M
- Enterprise Value
- $498.30M
- EPS (TTM)
- -$2.50
- Gross Profit (TTM)
- -$421.00K
- EBITDA (TTM)
- -$74.36M
- Year Range
- $2.15 - $28.44
- Target Price
- $31.50
- ROA (TTM)
- -26.90%
- ROE (TTM)
- -30.53%
Share Price Chart
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Performance
ANRO Performance Chart
Alto Neuroscience, Inc (ANRO) is up 28.8% since the beginning of the year. At $23 per share, ANRO is trading 19.4% below its 52-week high of $28.
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Returns By Period
Alto Neuroscience, Inc (ANRO) has returned 28.82% so far this year and 919.11% over the past 12 months.
Alto Neuroscience, Inc
- 1D
- 0.84%
- 1M
- 8.06%
- YTD
- 28.82%
- 6M
- 14.42%
- 1Y
- 919.11%
- 3Y*
- —
- 5Y*
- —
- 10Y*
- —
Benchmark (S&P 500 Index)
- 1D
- -0.37%
- 1M
- -0.01%
- YTD
- 9.16%
- 6M
- 8.64%
- 1Y
- 25.22%
- 3Y*
- 19.78%
- 5Y*
- 11.99%
- 10Y*
- 13.88%
ANRO Monthly Returns History
Based on dividend-adjusted daily data since Feb 2, 2024, ANRO's average daily return is +0.29%, while the average monthly return is +7.59%. At this rate, an investment would double in approximately 0.8 years.
Historically, 55% of months were positive and 45% were negative. The best month was Oct 2025 with a return of +253.0%, while the worst month was Oct 2024 at -66.0%. The longest winning streak lasted 4 consecutive months, and the longest losing streak was 2 months.
On a daily basis, ANRO closed higher 52% of trading days. The best single day was Oct 20, 2025 with a return of +80.9%, while the worst single day was Oct 23, 2024 at -70.0%.
| Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec | Total | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026 | -13.03% | 27.20% | 14.17% | 14.15% | -21.78% | 14.25% | 28.82% | ||||||
| 2025 | 1.42% | -34.73% | -22.86% | 15.28% | 3.61% | -14.73% | 39.55% | 19.87% | 9.24% | 252.99% | -2.40% | 28.52% | 320.80% |
| 2024 | -30.00% | -0.32% | 1.04% | -22.89% | -10.62% | 0.84% | 18.83% | -10.69% | -66.00% | 13.37% | -4.08% | -80.77% |
Benchmark Metrics
Alto Neuroscience, Inc has an annualized alpha of 64.32%, beta of 1.21, and R2 of 0.03 versus S&P 500 Index. Calculated based on daily prices since February 02, 2024.
- This stock participated in 268.44% of S&P 500 Index downside but only 157.65% of its upside - more exposed to losses than it benefited from rallies.
- R2 of 0.03 means this stock moves largely independently of S&P 500 Index - capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.
- Alpha
- 64.32%
- Beta
- 1.21
- R²
- 0.03
- Upside Capture
- 157.65%
- Downside Capture
- 268.44%
Return for Risk
Risk / Return Rank
ANRO ranks 99 for risk / return — in the top 99% of stocks on our site. This means strong returns relative to risk — exactly what professional investors look for. Well-suited for investors who want to maximize return per unit of risk.
Return / Risk — by metrics
The table below present risk-adjusted performance metrics for Alto Neuroscience, Inc (ANRO) and compare them to S&P 500 Index.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| ANRO | Benchmark | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +5.20 | ||
| Sortino ratioReturn per unit of downside risk | +2.90 | ||
| Omega ratioGain probability vs. loss probability | 1.72 | 1.37 | +0.35 |
| Calmar ratioReturn relative to maximum drawdown | 27.15 | 2.78 | +24.37 |
| Martin ratioReturn relative to average drawdown | 70.91 | 12.44 | +58.47 |
Dividends
Dividend History
Drawdowns
Drawdowns Chart
The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.
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Worst Drawdowns
The table below displays the maximum drawdowns of the Alto Neuroscience, Inc. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.
The maximum drawdown for the Alto Neuroscience, Inc was 91.82%, occurring on Apr 4, 2025. Recovery took 233 trading sessions.
The current Alto Neuroscience, Inc drawdown is 17.28%.
Related event | Drawdown | Fall | Recovery | Underwater |
|---|---|---|---|---|
2025 selloff2025 | -91.82%Apr 2025 | 1y 2mo | 11mo 11d | 2y 1moFeb 2024 - Mar 2026 |
2026 bear market2026 | -34.20%Jun 2026 | 1mo 19d | — | 2mo 4dApr 2026 - now |
2026 correction2026 | -17.74%Mar 2026 | 13d | 14d | 27dMar 2026 - Apr 2026 |
2026 pullback2026 | -3.56%Mar 2026 | 0s | 4d | 4dMar 2026 - Mar 2026 |
2026 pullback2026 | -1.36%Apr 2026 | 0s | 1d | 1dApr 2026 - Apr 2026 |
Drawdown Indicators
| ANRO | Benchmark | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -91.82% | -56.78% | -35.04% |
Max Drawdown (1Y)Largest decline over 1 year | -34.20% | -9.10% | -25.10% |
Max Drawdown (3Y)Largest decline over 3 years | — | -18.90% | — |
Max Drawdown (5Y)Largest decline over 5 years | — | -25.43% | — |
Max Drawdown (10Y)Largest decline over 10 years | — | -33.92% | — |
Current DrawdownCurrent decline from peak | -17.28% | -1.80% | -15.48% |
Average DrawdownAverage peak-to-trough decline | -53.30% | -10.71% | -42.59% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 13.07% | 2.03% | +11.04% |
Volatility
Volatility Chart
The chart below shows the rolling one-month volatility.
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Financials
Financial Performance
The chart below illustrates the trends in the financial health of Alto Neuroscience, Inc over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.
Valuation
The Valuation section provides an overview of how Alto Neuroscience, Inc is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.
PB Ratio
The chart illustrates the Price-to-Book (P/B) ratio for ANRO in comparison with other companies in the Biotechnology industry. Currently, ANRO has a P/B value of 3.1. This P/B ratio is in line with the industry average, suggesting the stock is valued fairly in relation to its book value.
Income Statement
| TTM | |
|---|---|
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Total Revenue | — |
Cost Of Revenue | — |
Gross Profit | — |
Operating Expenses | — |
Selling, General & Admin Expenses | — |
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Total Operating Expenses | — |
Income | — |
Income Before Tax | — |
Operating Income | — |
EBITDA | — |
EBIT | — |
Earnings From Continuing Operations | — |
Net Income | — |
Income Tax Expense | — |
Other Non-Operating Income (Expenses) | — |
Extraordinary Items | — |
Discontinued Operations | — |
Effect Of Accounting Charges | — |
Non Recurring | — |
Minority Interest | — |
Other Items | — |
Interest Income | — |
Interest Expense | — |
Net Interest Income | — |
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