CNCR vs. IBRN

Last updated Apr 3, 2026

Compare and contrast key facts about Loncar Cancer Immunotherapy ETF (CNCR) and iShares Neuroscience and Healthcare ETF (IBRN).

CNCR and IBRN are both exchange-traded funds (ETFs), meaning they are traded on stock exchanges and can be bought and sold throughout the day. CNCR is a passively managed fund by Exchange Traded Concepts that tracks the performance of the Loncar Cancer Immunotherapy Index. It was launched on Oct 13, 2015. IBRN is a passively managed fund by iShares that tracks the performance of the NYSE FactSet Global Neuro Biopharma and MedTech Index. It was launched on Aug 24, 2022. Both CNCR and IBRN are passive ETFs, meaning that they are not actively managed but aim to replicate the performance of the underlying index as closely as possible.

Performance

CNCR vs. IBRN - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Loncar Cancer Immunotherapy ETF (CNCR) and iShares Neuroscience and Healthcare ETF (IBRN). The values are adjusted to include any dividend payments, if applicable.

CNCR vs. IBRN - Yearly Performance Comparison

	2026 (YTD)
CNCR Loncar Cancer Immunotherapy ETF	0.00%
IBRN iShares Neuroscience and Healthcare ETF	2.85%

Returns By Period

CNCR

• 1D: 0.00%
• 1M: 0.00%
• YTD: —
• 6M: —
• 1Y: —
• 3Y*: —
• 5Y*: —
• 10Y*: —

IBRN

• 1D: 0.07%
• 1M: 7.54%
• YTD: 3.07%
• 6M: 22.58%
• 1Y: 54.30%
• 3Y*: 12.16%
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

CNCR vs. IBRN - Expense Ratio Comparison

CNCR has a 0.79% expense ratio, which is higher than IBRN's 0.47% expense ratio.

CNCR

Loncar Cancer Immunotherapy ETF

IBRN

iShares Neuroscience and Healthcare ETF

Return for Risk

CNCR vs. IBRN — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

IBRN

IBRN Risk / Return Rank: 87
IBRN Sharpe Ratio Rank: 87
IBRN Sortino Ratio Rank: 88
IBRN Omega Ratio Rank: 78
IBRN Calmar Ratio Rank: 90
IBRN Martin Ratio Rank: 89

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

CNCR vs. IBRN - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Loncar Cancer Immunotherapy ETF (CNCR) and iShares Neuroscience and Healthcare ETF (IBRN). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Risk / return metrics aren't available yet — we need at least 12 months of trading data to calculate them.

Sharpe Ratios by Period

	CNCR	IBRN	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	—	1.88	—
Sharpe Ratio (All Time) Calculated using the full available price history	—	0.37	—

Dividends

CNCR vs. IBRN - Dividend Comparison

CNCR has not paid dividends to shareholders, while IBRN's dividend yield for the trailing twelve months is around 0.96%.

	TTM	2025	2024	2023
CNCR Loncar Cancer Immunotherapy ETF	0.00%	0.00%	0.00%	0.00%
IBRN iShares Neuroscience and Healthcare ETF	0.96%	0.99%	0.40%	0.06%

Drawdowns

CNCR vs. IBRN - Drawdown Comparison

The maximum CNCR drawdown since its inception was 0.00%, smaller than the maximum IBRN drawdown of -35.38%. Use the drawdown chart below to compare losses from any high point for CNCR and IBRN.

Drawdown Indicators

	CNCR	IBRN	Difference
Max Drawdown Largest peak-to-trough decline	0.00%	-35.38%	+35.38%
Max Drawdown (1Y) Largest decline over 1 year	—	-11.97%	—
Current Drawdown Current decline from peak	0.00%	-0.67%	+0.67%
Average Drawdown Average peak-to-trough decline	0.00%	-10.18%	+10.18%
Ulcer Index Depth and duration of drawdowns from previous peaks	—	4.37%	—

Volatility

Volatility by Period

	CNCR	IBRN	Difference
Volatility (1M) Calculated over the trailing 1-month period	—	11.92%	—
Volatility (6M) Calculated over the trailing 6-month period	—	19.63%	—
Volatility (1Y) Calculated over the trailing 1-year period	0.00%	29.09%	-29.09%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	0.00%	25.37%	-25.37%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	0.00%	25.37%	-25.37%