CDNA vs. SMMT
CDNA (CareDx, Inc) and SMMT (Summit Therapeutics Inc.) are both stocks. Both are in the Healthcare sector — CDNA in Diagnostics & Research, SMMT in Biotechnology. Over the past 10 years, CDNA returned 18.09%/yr vs 5.97%/yr for SMMT. At a 0.15 correlation, their price movements are largely independent.
Performance
CDNA vs. SMMT - Performance Comparison
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Returns By Period
In the year-to-date period, CDNA achieves a 32.96% return, which is significantly higher than SMMT's -18.35% return. Over the past 10 years, CDNA has outperformed SMMT with an annualized return of 18.09%, while SMMT has yielded a comparatively lower 5.97% annualized return.
CDNA
- 1D
- -4.32%
- 1M
- 15.81%
- YTD
- 32.96%
- 6M
- 25.12%
- 1Y
- 31.57%
- 3Y*
- 47.04%
- 5Y*
- -23.19%
- 10Y*
- 18.09%
SMMT
- 1D
- 3.85%
- 1M
- -14.08%
- YTD
- -18.35%
- 6M
- -21.32%
- 1Y
- -30.54%
- 3Y*
- 75.32%
- 5Y*
- 17.16%
- 10Y*
- 5.97%
CDNA vs. SMMT - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
CDNA CareDx, Inc | 32.96% | -12.00% | 78.42% | 5.17% | -74.91% | -37.23% | 235.88% | -14.20% | 242.51% | 171.85% |
SMMT Summit Therapeutics Inc. | -18.35% | -1.99% | 583.72% | -38.59% | 57.99% | -42.77% | 193.75% | 39.13% | -89.62% | 29.44% |
Correlation
The correlation between CDNA and SMMT is 0.24, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.24 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.27 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.26 |
Correlation (10Y) Calculated over the trailing 10-year period | 0.16 |
Correlation (All Time) Calculated using the full available price history since Mar 5, 2015 | 0.15 |
The correlation between CDNA and SMMT shifts across timeframes, from 0.15 (all time) to 0.27 (3 years), reflecting how their relationship changes across market environments.
Fundamentals
CDNA:
$1.33B
SMMT:
$11.07B
CDNA:
-$0.15
SMMT:
-$1.60
CDNA:
4.24
SMMT:
20.28
CDNA:
$412.82M
SMMT:
$0.00
CDNA:
$198.97M
SMMT:
-$83.36K
CDNA:
$4.15M
SMMT:
-$738.34M
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Return for Risk
CDNA vs. SMMT — Risk / Return Rank
CDNA
SMMT
CDNA vs. SMMT - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for CareDx, Inc (CDNA) and Summit Therapeutics Inc. (SMMT). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| CDNA | SMMT | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +0.84 | ||
| Sortino ratioReturn per unit of downside risk | +1.21 | ||
| Omega ratioGain probability vs. loss probability | 1.17 | 0.98 | +0.19 |
| Calmar ratioReturn relative to maximum drawdown | 0.72 | -0.55 | +1.27 |
| Martin ratioReturn relative to average drawdown | 1.50 | -0.86 | +2.36 |
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Drawdowns
CDNA vs. SMMT - Drawdown Comparison
The maximum CDNA drawdown since its inception was -94.87%, roughly equal to the maximum SMMT drawdown of -95.75%. Use the drawdown chart below to compare losses from any high point for CDNA and SMMT.
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Drawdown Indicators
| CDNA | SMMT | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -94.87% | -95.75% | +0.88% |
Max Drawdown (1Y)Largest decline over 1 year | -43.92% | -55.49% | +11.57% |
Max Drawdown (3Y)Largest decline over 3 years | -65.96% | -64.44% | -1.52% |
Max Drawdown (5Y)Largest decline over 5 years | -94.85% | -91.78% | -3.07% |
Max Drawdown (10Y)Largest decline over 10 years | -94.87% | -95.75% | +0.88% |
Current DrawdownCurrent decline from peak | -73.80% | -61.09% | -12.71% |
Average DrawdownAverage peak-to-trough decline | -53.75% | -57.63% | +3.88% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 21.10% | 35.70% | -14.60% |
Volatility
CDNA vs. SMMT - Volatility Comparison
The current volatility for CareDx, Inc (CDNA) is 16.23%, while Summit Therapeutics Inc. (SMMT) has a volatility of 19.19%. This indicates that CDNA experiences smaller price fluctuations and is considered to be less risky than SMMT based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| CDNA | SMMT | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 16.23% | 19.19% | -2.96% |
Volatility (6M)Calculated over the trailing 6-month period | 45.88% | 56.82% | -10.94% |
Volatility (1Y)Calculated over the trailing 1-year period | 72.34% | 75.80% | -3.46% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 77.50% | 185.23% | -107.73% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 78.19% | 144.54% | -66.35% |
Dividends
CDNA vs. SMMT - Dividend Comparison
Neither CDNA nor SMMT has paid dividends to shareholders.
Financials
CDNA vs. SMMT - Financials Comparison
This section allows you to compare key financial metrics between CareDx, Inc and Summit Therapeutics Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
Frequently Asked Questions
CDNA and SMMT have a correlation of 0.24, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
SMMT has higher volatility (19.19%) compared to CDNA (16.23%). In terms of maximum drawdown, CDNA dropped -94.87% vs SMMT's -95.75%.
CDNA currently has the higher Sharpe Ratio (0.44 vs -0.41), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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