BTEC vs. SBIO

Last updated Jun 5, 2026

BTEC (Principal Healthcare Innovators Index ETF) and SBIO (ALPS Medical Breakthroughs ETF) are both Health & Biotech Equities funds - BTEC tracks the NASDAQ U.S. Health Care Innovators Index while SBIO tracks the S-Network Medical Breakthroughs Index. Both are passively managed. BTEC charges 0.42%/yr vs 0.50%/yr for SBIO.

Performance

BTEC vs. SBIO - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Principal Healthcare Innovators Index ETF (BTEC) and ALPS Medical Breakthroughs ETF (SBIO). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

BTEC

• 1D: 0.00%
• 1M: 0.00%
• YTD: —
• 6M: —
• 1Y: —
• 3Y*: —
• 5Y*: —
• 10Y*: —

SBIO

• 1D: 2.35%
• 1M: -5.55%
• YTD: 1.95%
• 6M: 4.13%
• 1Y: 68.86%
• 3Y*: 18.38%
• 5Y*: 3.16%
• 10Y*: 8.03%

*Multi-year figures are annualized to reflect compound growth (CAGR)

BTEC vs. SBIO - Yearly Performance Comparison

	2026 (YTD)
BTEC Principal Healthcare Innovators Index ETF	0.00%
SBIO ALPS Medical Breakthroughs ETF	2.41%

BTEC vs. SBIO - Sectors Allocation Comparison

Sectors	BTEC	SBIO
Healthcare	99.4%	100.0%
Industrials	0.6%	-
Basic Materials	-	-
Communication Services	-	-
Consumer Cyclical	-	-
Consumer Defensive	-	-
Energy	-	-
Financial Services	-	-0.0%
Real Estate	-	-
Technology	-	-
Utilities	-	-

Return for Risk

BTEC vs. SBIO — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

SBIO

SBIO Risk / Return Rank: 76
SBIO Sharpe Ratio Rank: 74
SBIO Sortino Ratio Rank: 72
SBIO Omega Ratio Rank: 63
SBIO Calmar Ratio Rank: 90
SBIO Martin Ratio Rank: 82

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

BTEC vs. SBIO - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Principal Healthcare Innovators Index ETF (BTEC) and ALPS Medical Breakthroughs ETF (SBIO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Risk / return metrics aren't available yet — we need at least 12 months of trading data to calculate them.

Sharpe Ratios by Period

	BTEC	SBIO	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	—	2.35	—
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	—	0.09	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	0.24	—
Sharpe Ratio (All Time) Calculated using the full available price history	—	0.22	—

Drawdowns

BTEC vs. SBIO - Drawdown Comparison

The maximum BTEC drawdown since its inception was 0.00%, smaller than the maximum SBIO drawdown of -63.06%. Use the drawdown chart below to compare losses from any high point for BTEC and SBIO.

Drawdown Indicators

	BTEC	SBIO	Difference
Max Drawdown Largest peak-to-trough decline	0.00%	-63.06%	+63.06%
Max Drawdown (1Y) Largest decline over 1 year	—	-12.66%	—
Max Drawdown (3Y) Largest decline over 3 years	—	-42.44%	—
Max Drawdown (5Y) Largest decline over 5 years	—	-53.10%	—
Max Drawdown (10Y) Largest decline over 10 years	—	-63.06%	—
Current Drawdown Current decline from peak	0.00%	-14.84%	+14.84%
Average Drawdown Average peak-to-trough decline	0.00%	-28.44%	+28.44%
Ulcer Index Depth and duration of drawdowns from previous peaks	—	4.26%	—

Volatility

Volatility by Period

	BTEC	SBIO	Difference
Volatility (1M) Calculated over the trailing 1-month period	—	9.85%	—
Volatility (6M) Calculated over the trailing 6-month period	—	22.76%	—
Volatility (1Y) Calculated over the trailing 1-year period	0.00%	29.40%	-29.40%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	0.00%	33.57%	-33.57%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	0.00%	33.18%	-33.18%

BTEC vs. SBIO - Expense Ratio Comparison

BTEC has a 0.42% expense ratio, which is lower than SBIO's 0.50% expense ratio.

Dividends

BTEC vs. SBIO - Dividend Comparison

Neither BTEC nor SBIO has paid dividends to shareholders.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017
BTEC Principal Healthcare Innovators Index ETF	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
SBIO ALPS Medical Breakthroughs ETF	0.00%	0.00%	3.55%	0.22%	0.00%	0.00%	0.00%	0.04%	2.79%	1.77%

Frequently Asked Questions

Which ETF is better, BTEC or SBIO?

On fees, BTEC is cheaper at 0.42% per year. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF is cheaper, BTEC or SBIO?

BTEC is cheaper with a 0.42% expense ratio, compared with 0.50% for SBIO.

Which ETF pays a higher dividend yield, BTEC or SBIO?

BTEC and SBIO have nearly identical dividend yields, around 0.00%.

What is the main difference between BTEC and SBIO?

BTEC tracks NASDAQ U.S. Health Care Innovators Index, while SBIO tracks S-Network Medical Breakthroughs Index. They also come from different issuers: Principal and SS&C. Their fees differ too: 0.42% for BTEC and 0.50% for SBIO.