BTAI vs. VOO
BTAI (BioXcel Therapeutics, Inc.) is a stock, while VOO (Vanguard S&P 500 ETF) is S&P 500 fund tracking the S&P 500 Index. Over the past 5 years, BTAI returned -69.75%/yr vs 13.13%/yr for VOO. At a 0.31 correlation, their price movements are largely independent.
Performance
BTAI vs. VOO - Performance Comparison
Loading charts...
Returns By Period
In the year-to-date period, BTAI achieves a -21.25% return, which is significantly lower than VOO's 8.19% return.
BTAI
- 1D
- -3.08%
- 1M
- 11.50%
- YTD
- -21.25%
- 6M
- -27.17%
- 1Y
- -23.64%
- 3Y*
- -83.89%
- 5Y*
- -69.75%
- 10Y*
- —
VOO
- 1D
- -1.42%
- 1M
- -1.34%
- YTD
- 8.19%
- 6M
- 7.24%
- 1Y
- 23.69%
- 3Y*
- 20.78%
- 5Y*
- 13.13%
- 10Y*
- 15.61%
BTAI vs. VOO - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | |
|---|---|---|---|---|---|---|---|---|---|
BTAI BioXcel Therapeutics, Inc. | -21.25% | -73.25% | -87.33% | -86.27% | 5.66% | -56.00% | 216.22% | 278.50% | -64.97% |
VOO Vanguard S&P 500 ETF | 8.19% | 17.82% | 24.98% | 26.32% | -18.17% | 28.79% | 18.32% | 31.37% | -6.57% |
Correlation
The correlation between BTAI and VOO is 0.27, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.27 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.30 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.33 |
Correlation (All Time) Calculated using the full available price history since Mar 8, 2018 | 0.31 |
Compare stocks, funds, or ETFs
Search for stocks, ETFs, and funds for a quick comparison or use the comparison tool for more options.
Return for Risk
BTAI vs. VOO — Risk / Return Rank
BTAI
VOO
BTAI vs. VOO - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for BioXcel Therapeutics, Inc. (BTAI) and Vanguard S&P 500 ETF (VOO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| BTAI | VOO | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -2.08 | ||
| Sortino ratioReturn per unit of downside risk | -1.79 | ||
| Omega ratioGain probability vs. loss probability | 1.09 | 1.35 | -0.25 |
| Calmar ratioReturn relative to maximum drawdown | -0.28 | 2.67 | -2.95 |
| Martin ratioReturn relative to average drawdown | -0.35 | 11.96 | -12.31 |
Loading charts...
Drawdowns
BTAI vs. VOO - Drawdown Comparison
The maximum BTAI drawdown since its inception was -99.90%, which is greater than VOO's maximum drawdown of -33.99%. Use the drawdown chart below to compare losses from any high point for BTAI and VOO.
Loading charts...
Drawdown Indicators
| BTAI | VOO | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -99.90% | -33.99% | -65.91% |
Max Drawdown (1Y)Largest decline over 1 year | -85.00% | -8.90% | -76.10% |
Max Drawdown (3Y)Largest decline over 3 years | -99.66% | -18.69% | -80.97% |
Max Drawdown (5Y)Largest decline over 5 years | -99.82% | -24.52% | -75.30% |
Max Drawdown (10Y)Largest decline over 10 years | — | -33.99% | — |
Current DrawdownCurrent decline from peak | -99.88% | -3.14% | -96.74% |
Average DrawdownAverage peak-to-trough decline | -63.39% | -3.68% | -59.71% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 67.05% | 1.99% | +65.06% |
Volatility
BTAI vs. VOO - Volatility Comparison
BioXcel Therapeutics, Inc. (BTAI) has a higher volatility of 21.69% compared to Vanguard S&P 500 ETF (VOO) at 4.83%. This indicates that BTAI's price experiences larger fluctuations and is considered to be riskier than VOO based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
Loading charts...
Volatility by Period
| BTAI | VOO | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 21.69% | 4.83% | +16.86% |
Volatility (6M)Calculated over the trailing 6-month period | 55.13% | 9.82% | +45.31% |
Volatility (1Y)Calculated over the trailing 1-year period | 141.19% | 12.46% | +128.73% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 121.41% | 16.91% | +104.50% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 117.69% | 18.02% | +99.67% |
Dividends
BTAI vs. VOO - Dividend Comparison
BTAI has not paid dividends to shareholders, while VOO's dividend yield for the trailing twelve months is around 1.05%.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
BTAI BioXcel Therapeutics, Inc. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
VOO Vanguard S&P 500 ETF | 1.05% | 1.13% | 1.24% | 1.46% | 1.69% | 1.25% | 1.54% | 1.88% | 2.06% | 1.78% | 2.02% | 2.10% |
Frequently Asked Questions
BTAI and VOO have a correlation of 0.27, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
BTAI has higher volatility (21.69%) compared to VOO (4.83%). In terms of maximum drawdown, BTAI dropped -99.90% vs VOO's -33.99%.
VOO currently has the higher Sharpe Ratio (1.91 vs -0.17), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
Find the right allocation for BTAI and VOO
Add both to a portfolio and optimize allocations for your target — whether that's maximizing returns, minimizing drawdowns, or balancing risk across holdings.
Open Portfolio Optimizer