BNGO vs. INO

Last updated Jun 4, 2026

BNGO (Bionano Genomics, Inc.) and INO (Inovio Pharmaceuticals, Inc.) are both stocks. Both are in the Healthcare sector — BNGO in Diagnostics & Research, INO in Biotechnology. Over the past 5 years, BNGO returned -80.06%/yr vs -58.74%/yr for INO. At a 0.32 correlation, their price movements are largely independent.

Performance

BNGO vs. INO - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Bionano Genomics, Inc. (BNGO) and Inovio Pharmaceuticals, Inc. (INO). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, BNGO achieves a -15.03% return, which is significantly higher than INO's -34.48% return.

BNGO

• 1D: 3.17%
• 1M: 4.84%
• YTD: -15.03%
• 6M: -24.86%
• 1Y: -64.77%
• 3Y*: -86.03%
• 5Y*: -80.06%
• 10Y*: —

INO

• 1D: -5.79%
• 1M: -0.00%
• YTD: -34.48%
• 6M: -43.56%
• 1Y: -46.23%
• 3Y*: -45.25%
• 5Y*: -58.74%
• 10Y*: -37.87%

*Multi-year figures are annualized to reflect compound growth (CAGR)

BNGO vs. INO - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018
BNGO Bionano Genomics, Inc.	-15.03%	-91.16%	-84.74%	-87.05%	-51.17%	-2.92%	148.39%	-76.34%	-25.04%
INO Inovio Pharmaceuticals, Inc.	-34.48%	-4.92%	-70.10%	-67.31%	-68.74%	-43.62%	168.18%	-17.50%	-15.43%

Correlation

The correlation between BNGO and INO is 0.25, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.25
Correlation (3Y) Calculated over the trailing 3-year period	0.33
Correlation (5Y) Calculated over the trailing 5-year period	0.45
Correlation (All Time) Calculated using the full available price history since Sep 24, 2018	0.32

The correlation between BNGO and INO shifts across timeframes, from 0.25 (1 year) to 0.45 (5 years), reflecting how their relationship changes across market environments.

Fundamentals

EPS BNGO : -$6.55 INO : -$63.15
Total Revenue (TTM) BNGO : $22.06M INO : $0.00
Gross Profit (TTM) BNGO : $3.32M INO : -$1.50M
EBITDA (TTM) BNGO : -$23.09M INO : -$22.01B

Return for Risk

BNGO vs. INO — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

BNGO

BNGO Risk / Return Rank: 11
BNGO Sharpe Ratio Rank: 9
BNGO Sortino Ratio Rank: 10
BNGO Omega Ratio Rank: 8
BNGO Calmar Ratio Rank: 9
BNGO Martin Ratio Rank: 18

INO

INO Risk / Return Rank: 19
INO Sharpe Ratio Rank: 18
INO Sortino Ratio Rank: 24
INO Omega Ratio Rank: 23
INO Calmar Ratio Rank: 14
INO Martin Ratio Rank: 13

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

BNGO vs. INO - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Bionano Genomics, Inc. (BNGO) and Inovio Pharmaceuticals, Inc. (INO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	BNGO	INO	Difference
Sharpe ratio Return per unit of total volatility	-0.80	-0.53	-0.28
Sortino ratio Return per unit of downside risk	-1.09	-0.27	-0.82
Omega ratio Gain probability vs. loss probability	0.83	0.96	-0.13
Calmar ratio Return relative to maximum drawdown	-0.83	-0.73	-0.10
Martin ratio Return relative to average drawdown	-1.08	-1.25	+0.17
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

BNGO vs. INO - Sharpe Ratio Comparison

The current BNGO Sharpe Ratio is -0.80, which is lower than the INO Sharpe Ratio of -0.53. The chart below compares the historical Sharpe Ratios of BNGO and INO, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	BNGO	INO	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.80	-0.53	-0.28
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.89	-0.68	-0.20
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	-0.41	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.34	-0.18	-0.16

Drawdowns

BNGO vs. INO - Drawdown Comparison

The maximum BNGO drawdown since its inception was -99.99%, roughly equal to the maximum INO drawdown of -99.95%. Use the drawdown chart below to compare losses from any high point for BNGO and INO.

Drawdown Indicators

	BNGO	INO	Difference
Max Drawdown Largest peak-to-trough decline	-99.99%	-99.95%	-0.04%
Max Drawdown (1Y) Largest decline over 1 year	-77.85%	-63.41%	-14.44%
Max Drawdown (3Y) Largest decline over 3 years	-99.76%	-92.44%	-7.32%
Max Drawdown (5Y) Largest decline over 5 years	-99.98%	-99.13%	-0.85%
Max Drawdown (10Y) Largest decline over 10 years	—	-99.72%	—
Current Drawdown Current decline from peak	-99.99%	-99.95%	-0.04%
Average Drawdown Average peak-to-trough decline	-83.70%	-92.35%	+8.65%
Ulcer Index Depth and duration of drawdowns from previous peaks	60.12%	37.06%	+23.06%

Volatility

BNGO vs. INO - Volatility Comparison

The current volatility for Bionano Genomics, Inc. (BNGO) is 11.64%, while Inovio Pharmaceuticals, Inc. (INO) has a volatility of 23.06%. This indicates that BNGO experiences smaller price fluctuations and is considered to be less risky than INO based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	BNGO	INO	Difference
Volatility (1M) Calculated over the trailing 1-month period	11.64%	23.06%	-11.42%
Volatility (6M) Calculated over the trailing 6-month period	45.02%	66.11%	-21.09%
Volatility (1Y) Calculated over the trailing 1-year period	81.10%	88.27%	-7.17%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	90.54%	86.08%	+4.46%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	191.66%	93.38%	+98.28%

Dividends

BNGO vs. INO - Dividend Comparison

Neither BNGO nor INO has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both BNGO and INO in my portfolio?

BNGO and INO have a correlation of 0.25, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, BNGO or INO?

INO has higher volatility (23.06%) compared to BNGO (11.64%). In terms of maximum drawdown, BNGO dropped -99.99% vs INO's -99.95%.

Which has better risk-adjusted returns?

INO currently has the higher Sharpe Ratio (-0.53 vs -0.80), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.