AYTU vs. COSM

Last updated Apr 1, 2026

Compare and contrast key facts about Aytu BioPharma, Inc. (AYTU) and Cosmos Health Inc. (COSM).

Performance

AYTU vs. COSM - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Aytu BioPharma, Inc. (AYTU) and Cosmos Health Inc. (COSM). The values are adjusted to include any dividend payments, if applicable.

AYTU vs. COSM - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
AYTU Aytu BioPharma, Inc.	5.00%	52.94%	-40.14%	-24.87%	-86.00%	-77.42%	-38.35%	22.41%	-98.22%	-88.85%
COSM Cosmos Health Inc.	-36.31%	-25.56%	-52.55%	-69.08%	-94.59%	-33.92%	131.82%	-45.00%	-60.78%	1,086.05%

Fundamentals

Market Cap AYTU : $27.40M COSM : $9.71M
EPS AYTU : -$2.02 COSM : -$0.62
PS Ratio AYTU : 0.53 COSM : 0.16
PB Ratio AYTU : 1.93 COSM : 0.42
Total Revenue (TTM) AYTU : $62.64M COSM : $59.79M
Gross Profit (TTM) AYTU : $41.34M COSM : $6.82M
EBITDA (TTM) AYTU : -$17.24M COSM : -$14.92M

Returns By Period

In the year-to-date period, AYTU achieves a 5.00% return, which is significantly higher than COSM's -36.31% return.

AYTU

• 1D: 3.61%
• 1M: 6.23%
• YTD: 5.00%
• 6M: 45.21%
• 1Y: 127.50%
• 3Y*: 6.82%
• 5Y*: -55.20%
• 10Y*: —

COSM

• 1D: -2.76%
• 1M: -19.35%
• YTD: -36.31%
• 6M: -71.42%
• 1Y: -27.25%
• 3Y*: -55.25%
• 5Y*: -69.74%
• 10Y*: -33.88%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

AYTU vs. COSM — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

AYTU

AYTU Risk / Return Rank: 86
AYTU Sharpe Ratio Rank: 76
AYTU Sortino Ratio Rank: 92
AYTU Omega Ratio Rank: 90
AYTU Calmar Ratio Rank: 85
AYTU Martin Ratio Rank: 85

COSM

COSM Risk / Return Rank: 32
COSM Sharpe Ratio Rank: 28
COSM Sortino Ratio Rank: 36
COSM Omega Ratio Rank: 35
COSM Calmar Ratio Rank: 29
COSM Martin Ratio Rank: 29

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

AYTU vs. COSM - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Aytu BioPharma, Inc. (AYTU) and Cosmos Health Inc. (COSM). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	AYTU	COSM	Difference
Sharpe ratio Return per unit of total volatility	1.09	-0.27	+1.36
Sortino ratio Return per unit of downside risk	3.01	0.27	+2.73
Omega ratio Gain probability vs. loss probability	1.39	1.03	+0.36
Calmar ratio Return relative to maximum drawdown	2.96	-0.40	+3.35
Martin ratio Return relative to average drawdown	7.81	-0.71	+8.53
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

AYTU vs. COSM - Sharpe Ratio Comparison

The current AYTU Sharpe Ratio is 1.09, which is higher than the COSM Sharpe Ratio of -0.27. The chart below compares the historical Sharpe Ratios of AYTU and COSM, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	AYTU	COSM	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.09	-0.27	+1.36
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.65	-0.44	-0.20
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	-0.09	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.36	-0.04	-0.31

Correlation

The correlation between AYTU and COSM is 0.09, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

AYTU vs. COSM - Dividend Comparison

Neither AYTU nor COSM has paid dividends to shareholders.

Tickers have no history of dividend payments

Drawdowns

AYTU vs. COSM - Drawdown Comparison

The maximum AYTU drawdown since its inception was -100.00%, roughly equal to the maximum COSM drawdown of -99.90%. Use the drawdown chart below to compare losses from any high point for AYTU and COSM.

Drawdown Indicators

	AYTU	COSM	Difference
Max Drawdown Largest peak-to-trough decline	-100.00%	-99.90%	-0.10%
Max Drawdown (1Y) Largest decline over 1 year	-42.47%	-74.82%	+32.35%
Max Drawdown (5Y) Largest decline over 5 years	-99.34%	-99.84%	+0.50%
Max Drawdown (10Y) Largest decline over 10 years	—	-99.90%	—
Current Drawdown Current decline from peak	-100.00%	-99.90%	-0.10%
Average Drawdown Average peak-to-trough decline	-95.05%	-63.96%	-31.09%
Ulcer Index Depth and duration of drawdowns from previous peaks	16.07%	41.57%	-25.50%

Volatility

AYTU vs. COSM - Volatility Comparison

The current volatility for Aytu BioPharma, Inc. (AYTU) is 9.71%, while Cosmos Health Inc. (COSM) has a volatility of 18.59%. This indicates that AYTU experiences smaller price fluctuations and is considered to be less risky than COSM based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	AYTU	COSM	Difference
Volatility (1M) Calculated over the trailing 1-month period	9.71%	18.59%	-8.88%
Volatility (6M) Calculated over the trailing 6-month period	39.38%	61.03%	-21.65%
Volatility (1Y) Calculated over the trailing 1-year period	117.87%	100.48%	+17.39%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	85.83%	158.27%	-72.44%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	190.04%	373.54%	-183.50%

Financials

AYTU vs. COSM - Profitability Comparison

The chart below illustrates the profitability comparison between Aytu BioPharma, Inc. and Cosmos Health Inc. over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

AYTU - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Apr 2026, Aytu BioPharma, Inc. reported a gross profit of 9.10M and revenue of 15.17M. Therefore, the gross margin over that period was 60.0%.

COSM - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Apr 2026, Cosmos Health Inc. reported a gross profit of 2.60M and revenue of 17.11M. Therefore, the gross margin over that period was 15.2%.

AYTU - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Apr 2026, Aytu BioPharma, Inc. reported an operating income of -1.97M and revenue of 15.17M, resulting in an operating margin of -13.0%.

COSM - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Apr 2026, Cosmos Health Inc. reported an operating income of -1.82M and revenue of 17.11M, resulting in an operating margin of -10.6%.

AYTU - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Apr 2026, Aytu BioPharma, Inc. reported a net income of -10.58M and revenue of 15.17M, resulting in a net margin of -69.8%.

COSM - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Apr 2026, Cosmos Health Inc. reported a net income of -5.35M and revenue of 17.11M, resulting in a net margin of -31.3%.