AYTU vs. COSM

Last updated Aug 1, 2026

AYTU (Aytu BioPharma, Inc.) and COSM (Cosmos Health Inc.) are both stocks. Both are in the Healthcare sector — AYTU in Drug Manufacturers - Specialty & Generic, COSM in Medical Distribution. Over the past 5 years, AYTU returned -51.06%/yr vs -44.24%/yr for COSM. Their 0.09 correlation means their historical movements had little consistent relationship.

Performance

AYTU vs. COSM - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Aytu BioPharma, Inc. (AYTU) and Cosmos Health Inc. (COSM). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, AYTU achieves a -14.23% return, which is significantly higher than COSM's -56.71% return.

AYTU

• 1D: 3.72%
• 1M: 3.24%
• 6M: -14.23%
• YTD: -14.23%
• 1Y: -7.08%
• 3Y*: 7.01%
• 5Y*: -51.06%
• 10Y*: —
• ALL TIME*: -67.05%

COSM

• 1D: 7.75%
• 1M: -9.07%
• 6M: -55.12%
• YTD: -56.71%
• 1Y: -75.03%
• 3Y*: -47.26%
• 5Y*: -44.24%
• 10Y*: -11.11%
• ALL TIME*: 5.00%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison

Position	Avg. Volume Value (2W)	Avg. Volume Value (1M)	Avg. Volume Value (3M)
AYTU Aytu BioPharma, Inc.	$55.01K	$54.55K	$81.73K
COSM Cosmos Health Inc.	$873.69K	$2.75M	$2.27M

AYTU vs. COSM - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
AYTU Aytu BioPharma, Inc.	-14.23%	52.94%	-40.14%	-24.87%	-86.00%	-77.42%	-38.35%	22.41%	-98.22%	-89.38%
COSM Cosmos Health Inc.	-56.71%	-25.56%	-52.55%	-69.08%	35.31%	-33.92%	131.82%	-45.00%	-60.78%	1,072.41%

Correlation

The correlation between AYTU and COSM is 0.15, which is low. Their historical price movements had little consistent relationship.

	Correlation
Correlation (1Y) Focuses on recent behavior, but can change the most.	0.15
Correlation (3Y) Balances recent behavior with more history.	0.10
Correlation (5Y) Shows whether the relationship held over a longer period.	0.10
Correlation (All Time) Calculated using the full available price history since Feb 1, 2017	0.09

Fundamentals

Market Cap AYTU : $23.94M COSM : $13.38M
EPS AYTU : -$2.55 COSM : -$0.61
PS Ratio AYTU : 0.53 COSM : 0.11
Total Revenue (TTM) AYTU : $56.60M COSM : $59.79M
Gross Profit (TTM) AYTU : $36.14M COSM : $6.82M
EBITDA (TTM) AYTU : -$27.34M COSM : -$14.92M

Return for Risk

AYTU vs. COSM — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

AYTU

AYTU Risk / Return Rank: 37
AYTU Sharpe Ratio Rank: 37
AYTU Sortino Ratio Rank: 37
AYTU Omega Ratio Rank: 37
AYTU Calmar Ratio Rank: 36
AYTU Martin Ratio Rank: 35

COSM

COSM Risk / Return Rank: 10
COSM Sharpe Ratio Rank: 11
COSM Sortino Ratio Rank: 8
COSM Omega Ratio Rank: 10
COSM Calmar Ratio Rank: 8
COSM Martin Ratio Rank: 13

The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

AYTU vs. COSM - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Aytu BioPharma, Inc. (AYTU) and Cosmos Health Inc. (COSM). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	AYTU	COSM	Difference
Sharpe ratio: Return per unit of total volatility	-0.16	-0.75	+0.59
Sortino ratio: Return per unit of downside risk	0.15	-1.34	+1.49
Omega ratio: Gain probability vs. loss probability	1.02	0.85	+0.17
Calmar ratio: Return relative to maximum drawdown	-0.24	-0.89	+0.65
Martin ratio: Return relative to average drawdown	-0.49	-1.26	+0.77

AYTU vs. COSM - Sharpe Ratio Comparison

The current AYTU Sharpe Ratio is -0.16, which is higher than the COSM Sharpe Ratio of -0.75. The chart below compares the historical Sharpe Ratios of AYTU and COSM, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

AYTU vs. COSM - Drawdown Comparison

The maximum AYTU drawdown since its inception was -100.00%, roughly equal to the maximum COSM drawdown of -99.42%. Use the drawdown chart below to compare losses from any high point for AYTU and COSM.

Drawdown Indicators

	AYTU	COSM	Difference
Max Drawdown Largest peak-to-trough decline	-100.00%	-99.42%	-0.58%
Max Drawdown (1Y) Largest decline over 1 year	-35.47%	-86.22%	+50.75%
Max Drawdown (3Y) Largest decline over 3 years	-70.24%	-90.94%	+20.70%
Max Drawdown (5Y) Largest decline over 5 years	-98.74%	-99.25%	+0.51%
Max Drawdown (10Y) Largest decline over 10 years	—	-99.42%	—
Current Drawdown Current decline from peak	-100.00%	-99.06%	-0.94%
Average Drawdown Average peak-to-trough decline	-95.33%	-63.46%	-31.87%
Ulcer Index Depth and duration of drawdowns from previous peaks	17.59%	60.96%	-43.37%

Volatility

AYTU vs. COSM - Volatility Comparison

The current volatility for Aytu BioPharma, Inc. (AYTU) is 10.72%, while Cosmos Health Inc. (COSM) has a volatility of 38.38%. This indicates that AYTU experiences smaller price fluctuations and is considered to be less risky than COSM based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	AYTU	COSM	Difference
Volatility (1M) Calculated over the trailing 1-month period	10.72%	38.38%	-27.66%
Volatility (6M) Calculated over the trailing 6-month period	31.58%	64.91%	-33.33%
Volatility (1Y) Calculated over the trailing 1-year period	54.31%	102.71%	-48.40%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	85.24%	3,082.78%	-2,997.54%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	186.78%	2,217.60%	-2,030.82%

Dividends

AYTU vs. COSM - Dividend Comparison

Neither AYTU nor COSM has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both AYTU and COSM in my portfolio?

AYTU and COSM have a correlation of 0.15, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, AYTU or COSM?

COSM has higher volatility (38.38%) compared to AYTU (10.72%). In terms of maximum drawdown, AYTU dropped -100.00% vs COSM's -99.42%.

Which has better risk-adjusted returns?

AYTU currently has the higher Sharpe Ratio (-0.16 vs -0.75), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.