ANAB vs. AGPU

Last updated Jun 4, 2026

ANAB (AnaptysBio, Inc.) and AGPU (Axe Compute Inc.) are both stocks. ANAB operates in Biotechnology (Healthcare), while AGPU operates in Software - Infrastructure (Technology). Over the past 5 years, ANAB returned 27.51%/yr vs -55.48%/yr for AGPU. At a 0.10 correlation, their price movements are largely independent.

Performance

ANAB vs. AGPU - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in AnaptysBio, Inc. (ANAB) and Axe Compute Inc. (AGPU). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, ANAB achieves a 58.54% return, which is significantly higher than AGPU's 13.71% return.

ANAB

• 1D: -0.04%
• 1M: -26.57%
• YTD: 58.54%
• 6M: 75.64%
• 1Y: 226.79%
• 3Y*: 60.13%
• 5Y*: 27.51%
• 10Y*: —

AGPU

• 1D: -7.19%
• 1M: 56.35%
• YTD: 13.71%
• 6M: 47.55%
• 1Y: -45.31%
• 3Y*: -46.45%
• 5Y*: -55.48%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

ANAB vs. AGPU - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018
ANAB AnaptysBio, Inc.	58.54%	266.16%	-38.19%	-30.88%	-10.82%	61.63%	32.31%	-74.53%	-42.28%
AGPU Axe Compute Inc.	13.71%	-41.87%	-75.08%	-46.35%	-67.79%	29.97%	-71.94%	-57.84%	-26.30%

Correlation

The correlation between ANAB and AGPU is 0.03, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.03
Correlation (3Y) Calculated over the trailing 3-year period	0.11
Correlation (5Y) Calculated over the trailing 5-year period	0.12
Correlation (All Time) Calculated using the full available price history since Jan 30, 2018	0.10

Fundamentals

Market Cap ANAB : $1.47B AGPU : $141.70M
EPS ANAB : -$0.91 AGPU : -$25.65
PS Ratio ANAB : 6.50 AGPU : 589.72
PB Ratio ANAB : 115.33 AGPU : 2.97
Total Revenue (TTM) ANAB : $232.39M AGPU : $125.28K
Gross Profit (TTM) ANAB : $245.59M AGPU : $52.66K
EBITDA (TTM) ANAB : $52.72M AGPU : -$232.85M

Return for Risk

ANAB vs. AGPU — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

ANAB

ANAB Risk / Return Rank: 94
ANAB Sharpe Ratio Rank: 95
ANAB Sortino Ratio Rank: 93
ANAB Omega Ratio Rank: 92
ANAB Calmar Ratio Rank: 96
ANAB Martin Ratio Rank: 96

AGPU

AGPU Risk / Return Rank: 39
AGPU Sharpe Ratio Rank: 32
AGPU Sortino Ratio Rank: 56
AGPU Omega Ratio Rank: 55
AGPU Calmar Ratio Rank: 25
AGPU Martin Ratio Rank: 27

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

ANAB vs. AGPU - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for AnaptysBio, Inc. (ANAB) and Axe Compute Inc. (AGPU). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	ANAB	AGPU	Difference
Sharpe ratio Return per unit of total volatility	3.24	-0.23	+3.47
Sortino ratio Return per unit of downside risk	3.63	1.04	+2.59
Omega ratio Gain probability vs. loss probability	1.48	1.13	+0.35
Calmar ratio Return relative to maximum drawdown	8.11	-0.49	+8.60
Martin ratio Return relative to average drawdown	20.93	-0.78	+21.71
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

ANAB vs. AGPU - Sharpe Ratio Comparison

The current ANAB Sharpe Ratio is 3.24, which is higher than the AGPU Sharpe Ratio of -0.23. The chart below compares the historical Sharpe Ratios of ANAB and AGPU, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	ANAB	AGPU	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	3.24	-0.23	+3.47
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.42	-0.39	+0.82
Sharpe Ratio (All Time) Calculated using the full available price history	0.23	-0.40	+0.63

Drawdowns

ANAB vs. AGPU - Drawdown Comparison

The maximum ANAB drawdown since its inception was -92.08%, smaller than the maximum AGPU drawdown of -99.97%. Use the drawdown chart below to compare losses from any high point for ANAB and AGPU.

Drawdown Indicators

	ANAB	AGPU	Difference
Max Drawdown Largest peak-to-trough decline	-92.08%	-99.97%	+7.89%
Max Drawdown (1Y) Largest decline over 1 year	-28.15%	-92.17%	+64.02%
Max Drawdown (3Y) Largest decline over 3 years	-69.32%	-98.58%	+29.26%
Max Drawdown (5Y) Largest decline over 5 years	-69.32%	-99.70%	+30.38%
Current Drawdown Current decline from peak	-40.21%	-99.81%	+59.60%
Average Drawdown Average peak-to-trough decline	-64.74%	-83.27%	+18.53%
Ulcer Index Depth and duration of drawdowns from previous peaks	10.92%	58.43%	-47.51%

Volatility

ANAB vs. AGPU - Volatility Comparison

The current volatility for AnaptysBio, Inc. (ANAB) is 11.47%, while Axe Compute Inc. (AGPU) has a volatility of 50.14%. This indicates that ANAB experiences smaller price fluctuations and is considered to be less risky than AGPU based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	ANAB	AGPU	Difference
Volatility (1M) Calculated over the trailing 1-month period	11.47%	50.14%	-38.67%
Volatility (6M) Calculated over the trailing 6-month period	46.57%	151.78%	-105.21%
Volatility (1Y) Calculated over the trailing 1-year period	70.75%	201.73%	-130.98%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	65.34%	141.04%	-75.70%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	75.51%	126.03%	-50.52%

Dividends

ANAB vs. AGPU - Dividend Comparison

Neither ANAB nor AGPU has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both ANAB and AGPU in my portfolio?

ANAB and AGPU have a correlation of 0.03, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, ANAB or AGPU?

AGPU has higher volatility (50.14%) compared to ANAB (11.47%). In terms of maximum drawdown, ANAB dropped -92.08% vs AGPU's -99.97%.

Which has better risk-adjusted returns?

ANAB currently has the higher Sharpe Ratio (3.24 vs -0.23), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.