ALKS vs. DFTX
ALKS (Alkermes plc) and DFTX (Definium Therapeutics, Inc) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. Over the past 3 years, ALKS returned 13.16%/yr vs 89.71%/yr for DFTX. At a 0.19 correlation, their price movements are largely independent.
Performance
ALKS vs. DFTX - Performance Comparison
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Returns By Period
In the year-to-date period, ALKS achieves a 52.82% return, which is significantly lower than DFTX's 76.18% return.
ALKS
- 1D
- 3.48%
- 1M
- 25.14%
- YTD
- 52.82%
- 6M
- 44.80%
- 1Y
- 36.74%
- 3Y*
- 13.16%
- 5Y*
- 13.13%
- 10Y*
- -0.52%
DFTX
- 1D
- 3.19%
- 1M
- 8.46%
- YTD
- 76.18%
- 6M
- 97.57%
- 1Y
- 206.76%
- 3Y*
- 89.71%
- 5Y*
- —
- 10Y*
- —
ALKS vs. DFTX - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | |
|---|---|---|---|---|---|
ALKS Alkermes plc | 52.82% | -2.71% | 3.68% | 6.16% | -15.44% |
DFTX Definium Therapeutics, Inc | 76.18% | 92.39% | 90.16% | 66.36% | -76.86% |
Correlation
The correlation between ALKS and DFTX is 0.21, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.21 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.23 |
Correlation (All Time) Calculated using the full available price history since Jul 12, 2022 | 0.19 |
Fundamentals
ALKS:
$7.11B
DFTX:
$2.57B
ALKS:
$0.91
DFTX:
-$2.57
ALKS:
4.06
DFTX:
9.20
ALKS:
$1.56B
DFTX:
$0.00
ALKS:
$1.02B
DFTX:
$0.00
ALKS:
$249.70M
DFTX:
-$206.36M
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Return for Risk
ALKS vs. DFTX — Risk / Return Rank
ALKS
DFTX
ALKS vs. DFTX - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Alkermes plc (ALKS) and Definium Therapeutics, Inc (DFTX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| ALKS | DFTX | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -2.46 | ||
| Sortino ratioReturn per unit of downside risk | -2.06 | ||
| Omega ratioGain probability vs. loss probability | 1.19 | 1.42 | -0.23 |
| Calmar ratioReturn relative to maximum drawdown | 1.66 | 8.40 | -6.73 |
| Martin ratioReturn relative to average drawdown | 3.50 | 24.79 | -21.30 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| ALKS | DFTX | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 0.91 | 3.37 | -2.46 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | 0.35 | — | — |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | -0.01 | — | — |
Sharpe Ratio (All Time)Calculated using the full available price history | 0.10 | 0.31 | -0.22 |
Drawdowns
ALKS vs. DFTX - Drawdown Comparison
The maximum ALKS drawdown since its inception was -96.14%, which is greater than DFTX's maximum drawdown of -86.01%. Use the drawdown chart below to compare losses from any high point for ALKS and DFTX.
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Drawdown Indicators
| ALKS | DFTX | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -96.14% | -86.01% | -10.13% |
Max Drawdown (1Y)Largest decline over 1 year | -22.20% | -24.79% | +2.59% |
Max Drawdown (3Y)Largest decline over 3 years | -31.58% | -58.38% | +26.80% |
Max Drawdown (5Y)Largest decline over 5 years | -33.18% | — | — |
Max Drawdown (10Y)Largest decline over 10 years | -80.58% | — | — |
Current DrawdownCurrent decline from peak | -56.39% | -2.48% | -53.91% |
Average DrawdownAverage peak-to-trough decline | -67.25% | -51.59% | -15.66% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 10.54% | 8.38% | +2.16% |
Volatility
ALKS vs. DFTX - Volatility Comparison
The current volatility for Alkermes plc (ALKS) is 13.20%, while Definium Therapeutics, Inc (DFTX) has a volatility of 15.93%. This indicates that ALKS experiences smaller price fluctuations and is considered to be less risky than DFTX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| ALKS | DFTX | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 13.20% | 15.93% | -2.73% |
Volatility (6M)Calculated over the trailing 6-month period | 30.12% | 38.84% | -8.72% |
Volatility (1Y)Calculated over the trailing 1-year period | 40.64% | 61.78% | -21.14% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 37.32% | 84.08% | -46.76% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 41.29% | 84.08% | -42.79% |
Dividends
ALKS vs. DFTX - Dividend Comparison
Neither ALKS nor DFTX has paid dividends to shareholders.
Financials
ALKS vs. DFTX - Financials Comparison
This section allows you to compare key financial metrics between Alkermes plc and Definium Therapeutics, Inc. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
Frequently Asked Questions
ALKS and DFTX have a correlation of 0.21, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
DFTX has higher volatility (15.93%) compared to ALKS (13.20%). In terms of maximum drawdown, ALKS dropped -96.14% vs DFTX's -86.01%.
DFTX currently has the higher Sharpe Ratio (3.37 vs 0.91), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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