2B78.DE vs. SC0T.DE
2B78.DE (iShares Healthcare Innovation UCITS ETF) and SC0T.DE (Invesco European Health Care Sector UCITS ETF) are both Health & Biotech Equities funds - 2B78.DE tracks the iSTOXX® FactSet Breakthrough Healthcare while SC0T.DE tracks the STOXX® Europe 600 Optimised Health Care. Both are passively managed. Over the past 5 years, 2B78.DE returned -1.74%/yr vs 4.81%/yr for SC0T.DE. A 0.65 correlation means they provide meaningful diversification when combined. 2B78.DE charges 0.40%/yr vs 0.20%/yr for SC0T.DE.
Performance
2B78.DE vs. SC0T.DE - Performance Comparison
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Returns By Period
In the year-to-date period, 2B78.DE achieves a -2.07% return, which is significantly higher than SC0T.DE's -3.57% return.
2B78.DE
- 1D
- 0.41%
- 1M
- 1.41%
- YTD
- -2.07%
- 6M
- -3.15%
- 1Y
- 14.42%
- 3Y*
- 2.27%
- 5Y*
- -1.74%
- 10Y*
- —
SC0T.DE
- 1D
- 2.93%
- 1M
- 0.25%
- YTD
- -3.57%
- 6M
- -2.50%
- 1Y
- 2.66%
- 3Y*
- 2.80%
- 5Y*
- 4.81%
- 10Y*
- 5.80%
2B78.DE vs. SC0T.DE - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
2B78.DE iShares Healthcare Innovation UCITS ETF | -2.07% | 5.50% | 7.24% | -0.29% | -19.03% | 1.15% | 38.75% | 16.74% | 0.39% | 19.45% |
SC0T.DE Invesco European Health Care Sector UCITS ETF | -3.57% | 8.45% | 6.96% | 5.35% | -7.56% | 25.20% | -1.18% | 32.22% | -1.43% | 4.65% |
Correlation
The correlation between 2B78.DE and SC0T.DE is 0.70, which is moderate. They share some common price drivers but move independently often enough to provide real diversification benefit when combined.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.70 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.63 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.63 |
Correlation (All Time) Calculated using the full available price history since Sep 14, 2016 | 0.65 |
The correlation between 2B78.DE and SC0T.DE has been stable across timeframes, ranging from 0.63 to 0.70 - a consistent structural relationship.
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Return for Risk
2B78.DE vs. SC0T.DE — Risk / Return Rank
2B78.DE
SC0T.DE
2B78.DE vs. SC0T.DE - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for iShares Healthcare Innovation UCITS ETF (2B78.DE) and Invesco European Health Care Sector UCITS ETF (SC0T.DE). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| 2B78.DE | SC0T.DE | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +0.76 | ||
| Sortino ratioReturn per unit of downside risk | +1.04 | ||
| Omega ratioGain probability vs. loss probability | 1.17 | 1.05 | +0.12 |
| Calmar ratioReturn relative to maximum drawdown | 1.24 | 0.24 | +0.99 |
| Martin ratioReturn relative to average drawdown | 3.07 | 0.56 | +2.51 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| 2B78.DE | SC0T.DE | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 0.95 | 0.20 | +0.76 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | -0.10 | 0.32 | -0.42 |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | — | 0.37 | — |
Sharpe Ratio (All Time)Calculated using the full available price history | 0.31 | 0.63 | -0.32 |
Drawdowns
2B78.DE vs. SC0T.DE - Drawdown Comparison
The maximum 2B78.DE drawdown since its inception was -38.58%, which is greater than SC0T.DE's maximum drawdown of -26.52%. Use the drawdown chart below to compare losses from any high point for 2B78.DE and SC0T.DE.
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Drawdown Indicators
| 2B78.DE | SC0T.DE | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -38.58% | -26.52% | -12.06% |
Max Drawdown (1Y)Largest decline over 1 year | -12.05% | -12.87% | +0.82% |
Max Drawdown (3Y)Largest decline over 3 years | -25.32% | -21.67% | -3.65% |
Max Drawdown (5Y)Largest decline over 5 years | -36.99% | -21.67% | -15.32% |
Max Drawdown (10Y)Largest decline over 10 years | — | -26.52% | — |
Current DrawdownCurrent decline from peak | -19.03% | -9.59% | -9.44% |
Average DrawdownAverage peak-to-trough decline | -14.36% | -6.03% | -8.33% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 4.86% | 5.58% | -0.72% |
Volatility
2B78.DE vs. SC0T.DE - Volatility Comparison
The current volatility for iShares Healthcare Innovation UCITS ETF (2B78.DE) is 3.74%, while Invesco European Health Care Sector UCITS ETF (SC0T.DE) has a volatility of 5.31%. This indicates that 2B78.DE experiences smaller price fluctuations and is considered to be less risky than SC0T.DE based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| 2B78.DE | SC0T.DE | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 3.74% | 5.31% | -1.57% |
Volatility (6M)Calculated over the trailing 6-month period | 10.97% | 11.43% | -0.46% |
Volatility (1Y)Calculated over the trailing 1-year period | 15.67% | 15.98% | -0.31% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 17.91% | 14.84% | +3.07% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 18.79% | 15.39% | +3.40% |
2B78.DE vs. SC0T.DE - Expense Ratio Comparison
2B78.DE has a 0.40% expense ratio, which is higher than SC0T.DE's 0.20% expense ratio.
Dividends
2B78.DE vs. SC0T.DE - Dividend Comparison
Neither 2B78.DE nor SC0T.DE has paid dividends to shareholders.
Frequently Asked Questions
2B78.DE and SC0T.DE have a correlation of 0.70, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
On fees, SC0T.DE is cheaper at 0.20% per year. The better choice depends on whether you care most about return, fees, risk, or income.
SC0T.DE is cheaper with a 0.20% expense ratio, compared with 0.40% for 2B78.DE.
2B78.DE tracks iSTOXX® FactSet Breakthrough Healthcare, while SC0T.DE tracks STOXX® Europe 600 Optimised Health Care. They also come from different issuers: iShares and Invesco. Their fees differ too: 0.40% for 2B78.DE and 0.20% for SC0T.DE.
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