2B78.DE vs. IS3N.DE
2B78.DE (iShares Healthcare Innovation UCITS ETF) and IS3N.DE (iShares Core MSCI Emerging Markets IMI UCITS ETF (Acc)) are both exchange-traded funds - 2B78.DE is a Health & Biotech Equities fund tracking the iSTOXX® FactSet Breakthrough Healthcare, while IS3N.DE is a Emerging Markets Equities fund tracking the MSCI Emerging Markets Investable Market (IMI). Both are passively managed. Over the past 5 years, 2B78.DE returned -1.74%/yr vs 8.61%/yr for IS3N.DE. A 0.58 correlation means they provide meaningful diversification when combined. 2B78.DE charges 0.40%/yr vs 0.18%/yr for IS3N.DE.
Performance
2B78.DE vs. IS3N.DE - Performance Comparison
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Returns By Period
In the year-to-date period, 2B78.DE achieves a -2.07% return, which is significantly lower than IS3N.DE's 25.82% return.
2B78.DE
- 1D
- 0.41%
- 1M
- 1.41%
- YTD
- -2.07%
- 6M
- -3.15%
- 1Y
- 14.42%
- 3Y*
- 2.27%
- 5Y*
- -1.74%
- 10Y*
- —
IS3N.DE
- 1D
- -1.45%
- 1M
- 3.11%
- YTD
- 25.82%
- 6M
- 26.34%
- 1Y
- 45.77%
- 3Y*
- 19.99%
- 5Y*
- 8.61%
- 10Y*
- 10.00%
2B78.DE vs. IS3N.DE - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
2B78.DE iShares Healthcare Innovation UCITS ETF | -2.07% | 5.50% | 7.24% | -0.29% | -19.03% | 1.15% | 38.75% | 16.74% | 0.39% | 19.45% |
IS3N.DE iShares Core MSCI Emerging Markets IMI UCITS ETF (Acc) | 25.82% | 17.14% | 13.87% | 7.20% | -14.09% | 7.38% | 7.07% | 21.01% | -11.06% | 20.43% |
Correlation
The correlation between 2B78.DE and IS3N.DE is 0.43, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.43 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.47 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.51 |
Correlation (All Time) Calculated using the full available price history since Sep 14, 2016 | 0.58 |
The correlation between 2B78.DE and IS3N.DE shifts across timeframes, from 0.43 (1 year) to 0.58 (all time), reflecting how their relationship changes across market environments.
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Return for Risk
2B78.DE vs. IS3N.DE — Risk / Return Rank
2B78.DE
IS3N.DE
2B78.DE vs. IS3N.DE - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for iShares Healthcare Innovation UCITS ETF (2B78.DE) and iShares Core MSCI Emerging Markets IMI UCITS ETF (Acc) (IS3N.DE). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| 2B78.DE | IS3N.DE | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -1.74 | ||
| Sortino ratioReturn per unit of downside risk | -2.14 | ||
| Omega ratioGain probability vs. loss probability | 1.17 | 1.49 | -0.32 |
| Calmar ratioReturn relative to maximum drawdown | 1.24 | 4.42 | -3.19 |
| Martin ratioReturn relative to average drawdown | 3.07 | 16.00 | -12.93 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| 2B78.DE | IS3N.DE | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 0.95 | 2.69 | -1.74 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | -0.10 | 0.53 | -0.62 |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | — | 0.55 | — |
Sharpe Ratio (All Time)Calculated using the full available price history | 0.31 | 0.44 | -0.13 |
Drawdowns
2B78.DE vs. IS3N.DE - Drawdown Comparison
The maximum 2B78.DE drawdown since its inception was -38.58%, which is greater than IS3N.DE's maximum drawdown of -35.06%. Use the drawdown chart below to compare losses from any high point for 2B78.DE and IS3N.DE.
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Drawdown Indicators
| 2B78.DE | IS3N.DE | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -38.58% | -35.06% | -3.52% |
Max Drawdown (1Y)Largest decline over 1 year | -12.05% | -10.52% | -1.53% |
Max Drawdown (3Y)Largest decline over 3 years | -25.32% | -19.17% | -6.15% |
Max Drawdown (5Y)Largest decline over 5 years | -36.99% | -22.01% | -14.98% |
Max Drawdown (10Y)Largest decline over 10 years | — | -32.51% | — |
Current DrawdownCurrent decline from peak | -19.03% | -2.49% | -16.54% |
Average DrawdownAverage peak-to-trough decline | -14.36% | -9.30% | -5.06% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 4.86% | 2.91% | +1.95% |
Volatility
2B78.DE vs. IS3N.DE - Volatility Comparison
The current volatility for iShares Healthcare Innovation UCITS ETF (2B78.DE) is 3.74%, while iShares Core MSCI Emerging Markets IMI UCITS ETF (Acc) (IS3N.DE) has a volatility of 7.16%. This indicates that 2B78.DE experiences smaller price fluctuations and is considered to be less risky than IS3N.DE based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| 2B78.DE | IS3N.DE | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 3.74% | 7.16% | -3.42% |
Volatility (6M)Calculated over the trailing 6-month period | 10.97% | 14.69% | -3.72% |
Volatility (1Y)Calculated over the trailing 1-year period | 15.67% | 17.32% | -1.65% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 17.91% | 16.19% | +1.72% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 18.79% | 18.04% | +0.75% |
2B78.DE vs. IS3N.DE - Expense Ratio Comparison
2B78.DE has a 0.40% expense ratio, which is higher than IS3N.DE's 0.18% expense ratio.
Dividends
2B78.DE vs. IS3N.DE - Dividend Comparison
Neither 2B78.DE nor IS3N.DE has paid dividends to shareholders.
Frequently Asked Questions
2B78.DE and IS3N.DE have a correlation of 0.43, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
On fees, IS3N.DE is cheaper at 0.18% per year. The better choice depends on whether you care most about return, fees, risk, or income.
IS3N.DE is cheaper with a 0.18% expense ratio, compared with 0.40% for 2B78.DE.
2B78.DE is categorized as Health & Biotech Equities, while IS3N.DE is Emerging Markets Equities. 2B78.DE tracks iSTOXX® FactSet Breakthrough Healthcare, while IS3N.DE tracks MSCI Emerging Markets Investable Market (IMI). Their fees differ too: 0.40% for 2B78.DE and 0.18% for IS3N.DE.
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