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SPDR S&P US Health Care Select Sector UCITS ETF (ZPDH.DE) Alternatives

ETF · Currency in EUR · Last updated Jun 5, 2026

ZPDH.DE is a passive ETF by State Street tracking the investment results of the S&P Health Care Select Sector. ZPDH.DE launched on Jul 7, 2015 and has a 0.15% expense ratio.

SPDR S&P US Health Care Select Sector UCITS ETF (ZPDH.DE) belongs to the Health & Biotech Equities category. Below you'll find alternative ETFs from the same category, ranked by key criteria, plus funds that investors commonly compare with ZPDH.DE. Use the tables to find lower-cost options, better risk-adjusted returns, or a closer substitute for your current allocation.

Cheapest Alternatives to ZPDH.DE

ZPDH.DE charges 0.15% annually. There is 1 ETF in the Health & Biotech Equities category with a lower expense ratio, going as low as 0.12%.

SymbolNameExpense RatioAUMInception
XUHC.DE
Xtrackers MSCI USA Health Care UCITS ETF 1D0.12%—Sep 2017ZPDH.DE vs XUHC.DE
QDVG.DE
iShares S&P 500 Health Care Sector UCITS ETF (Acc)0.15%—Nov 2015ZPDH.DE vs QDVG.DE
DXSE.DE
Xtrackers MSCI Europe Health Care ESG Screened UCI...0.17%—Jun 2007ZPDH.DE vs DXSE.DE
SPYH.DE
SPDR MSCI Europe Health Care UCITS ETF0.18%—Dec 2014ZPDH.DE vs SPYH.DE
CBUF.DE
iShares MSCI World Health Care Sector ESG UCITS ET...0.18%—Oct 2019ZPDH.DE vs CBUF.DE

Best Risk-Adjusted Alternatives to ZPDH.DE

ZPDH.DE has a PortfoliosLab risk / return rank of 25. There are 9 ETFs in the Health & Biotech Equities category with higher risk-adjusted ranks, going as high as 71.

SymbolNameRisk / Return RankAUMInception
2B70.DE
iShares Nasdaq US Biotechnology UCITS ETF
71
—Oct 2017ZPDH.DE vs 2B70.DE
NBTK.DE
Invesco Nasdaq Biotech UCITS ETF
71
—Nov 2014ZPDH.DE vs NBTK.DE
GN0M.DE
Global X Genomics & Biotechnology UCITS ETF
58
—Nov 2021ZPDH.DE vs GN0M.DE
WRNA.DE
WisdomTree BioRevolution UCITS ETF USD Acc
56
—Dec 2021ZPDH.DE vs WRNA.DE
2B77.DE
iShares Ageing Population UCITS ETF
43
—Sep 2016ZPDH.DE vs 2B77.DE

Top Performing ZPDH.DE Alternatives (YTD)

ZPDH.DE is at -1.12% YTD. There are 7 ETFs in the Health & Biotech Equities category with higher YTD returns, going as high as 12.99%.

SymbolNameYTD ReturnAUMInception
GN0M.DE
Global X Genomics & Biotechnology UCITS ETF
12.99%
—Nov 2021ZPDH.DE vs GN0M.DE
WRNA.DE
WisdomTree BioRevolution UCITS ETF USD Acc
10.48%
—Dec 2021ZPDH.DE vs WRNA.DE
2B70.DE
iShares Nasdaq US Biotechnology UCITS ETF
4.53%
—Oct 2017ZPDH.DE vs 2B70.DE
NBTK.DE
Invesco Nasdaq Biotech UCITS ETF
4.27%
—Nov 2014ZPDH.DE vs NBTK.DE
2B77.DE
iShares Ageing Population UCITS ETF
2.83%
—Sep 2016ZPDH.DE vs 2B77.DE

Lowest Volatility Alternatives to ZPDH.DE

ZPDH.DE has 14.63% 1-year volatility. There are 8 ETFs in the Health & Biotech Equities category with lower 1-year volatility, going as low as 12.28%.

SymbolNameVolatility 1YAUMInception
2B77.DE
iShares Ageing Population UCITS ETF12.28%—Sep 2016ZPDH.DE vs 2B77.DE
XDWH.DE
Xtrackers MSCI World Health Care UCITS ETF 1C13.69%—Mar 2016ZPDH.DE vs XDWH.DE
LYPE.DE
Amundi MSCI World Health Care UCITS ETF EUR Acc13.82%—Aug 2010ZPDH.DE vs LYPE.DE
CBUF.DE
iShares MSCI World Health Care Sector ESG UCITS ET...13.98%—Oct 2019ZPDH.DE vs CBUF.DE
XUHC.DE
Xtrackers MSCI USA Health Care UCITS ETF 1D14.51%—Sep 2017ZPDH.DE vs XUHC.DE

Lowest Drawdown Alternatives to ZPDH.DE

ZPDH.DE has a 1-year max drawdown of -10.77%. There are 7 ETFs in the Health & Biotech Equities category with shallower 1-year drawdowns, going as shallow as -6.24%.

SymbolNameMax Drawdown 1YAUMInception
NBTK.DE
Invesco Nasdaq Biotech UCITS ETF
-6.24%
—Nov 2014ZPDH.DE vs NBTK.DE
2B70.DE
iShares Nasdaq US Biotechnology UCITS ETF
-6.33%
—Oct 2017ZPDH.DE vs 2B70.DE
2B77.DE
iShares Ageing Population UCITS ETF
-6.80%
—Sep 2016ZPDH.DE vs 2B77.DE
ETLI.DE
L&G Pharma Breakthrough UCITS ETF
-9.06%
—Jan 2018ZPDH.DE vs ETLI.DE
LYPE.DE
Amundi MSCI World Health Care UCITS ETF EUR Acc
-10.21%
—Aug 2010ZPDH.DE vs LYPE.DE

Other ETFs from State Street

The 10 most viewed State Street ETFs shown here include SPYL.DE, SPYY.DE, ZPRV.DE and span 7 categories.

SymbolNameCategoryRisk / Return RankYTD ReturnAUMInception
SPYL.DE
State Street SPDR S&P 500 UCITS ETF USD Unhedged (...S&P 500, Large Cap Blend Equities
69
11.37%
—Oct 2023ZPDH.DE vs SPYL.DE
SPYY.DE
SPDR MSCI ACWI UCITS ETFGlobal Equities
77
12.54%
—May 2011ZPDH.DE vs SPYY.DE
ZPRV.DE
SPDR MSCI USA Small Cap Value Weighted UCITS ETFSmall Cap Value Equities
74
14.58%
—Feb 2015ZPDH.DE vs ZPRV.DE
SPYI.DE
SPDR MSCI ACWI IMI UCITS ETFGlobal Equities
79
13.27%
—May 2011ZPDH.DE vs SPYI.DE
SPPW.DE
SPDR MSCI World UCITS ETFGlobal Equities
70
10.85%
—Feb 2019ZPDH.DE vs SPPW.DE
SPY5.DE
SPDR S&P 500 UCITS ETFS&P 500
69
11.39%
—Mar 2012ZPDH.DE vs SPY5.DE
ZPRX.DE
SPDR MSCI Europe Small Cap Value Weighted UCITS ET...Europe Equities
34
7.81%
—Feb 2015ZPDH.DE vs ZPRX.DE
SPYW.DE
SPDR S&P Euro Dividend Aristocrats UCITS ETF (Dist...Europe Equities
22
5.36%
—Feb 2012ZPDH.DE vs SPYW.DE
SPYM.DE
SPDR MSCI Emerging Markets UCITS ETFEmerging Markets Equities
85
27.39%
—May 2011ZPDH.DE vs SPYM.DE
SPPY.DE
State Street SPDR S&P 500 Leaders UCITS ETFS&P 500, ESG
78
11.08%
—Dec 2019ZPDH.DE vs SPPY.DE

Often Compared With ZPDH.DE

Investors most often compare ZPDH.DE with LHTC.DE, WHEA.AS, ^GSPC. These 20 comparison targets span 3 categories, based on PortfoliosLab usage data.

SymbolNameCategoryRisk / Return RankYTD ReturnAUMInception
LHTC.DE
Lyxor STOXX Europe 600 Healthcare UCITS ETF AccHealth & Biotech Equities
14
-2.55%
—Aug 2006ZPDH.DE vs LHTC.DE
WHEA.AS
SPDR MSCI World Health Care UCITS ETFHealth & Biotech Equities
21
-1.97%
—Apr 2016ZPDH.DE vs WHEA.AS
^GSPC
S&P 500 Index
80
10.79%
——ZPDH.DE vs ^GSPC
HWWA.L
HSBC Multi Factor Worldwide Equity UCITS ETFGlobal Equities
91
13.69%
818.36MJul 2014ZPDH.DE vs HWWA.L
VJPU.L
Vanguard FTSE Japan UCITS ETF USD Hedged AccJapan Equities
88
19.64%
4.45BJan 2020ZPDH.DE vs VJPU.L
FHLC
Fidelity MSCI Health Care Index ETFHealth & Biotech Equities
34
-1.05%
2.85BOct 2013ZPDH.DE vs FHLC
XLV
State Street Health Care Select Sector SPDR ETFHealth & Biotech Equities
31
-1.35%
38.66BDec 1998ZPDH.DE vs XLV
EHLT.DE
Lyxor STOXX Europe 600 Healthcare UCITS ETF DistHealth & Biotech Equities
14
-2.49%
—Jul 2020ZPDH.DE vs EHLT.DE
XGEN.DE
Xtrackers MSCI Genomic Healthcare Innovation UCITS...Health & Biotech Equities
32
-1.40%
—Jul 2022ZPDH.DE vs XGEN.DE
AGES.L
iShares Ageing Population UCITS ETFGlobal Equities
51
1.98%
589.02MSep 2016ZPDH.DE vs AGES.L
PPH
VanEck Vectors Pharmaceutical ETFHealth & Biotech Equities
36
2.63%
941.75MDec 2011ZPDH.DE vs PPH
DDOC.DE
Global X Telemedicine & Digital Health UCITS ETF A...Health & Biotech Equities
9
-1.35%
—Dec 2020ZPDH.DE vs DDOC.DE
WELS.DE
Amundi S&P Global Health Care ESG UCITS ETF EUR Ac...Health & Biotech Equities
16
-3.35%
—Sep 2022ZPDH.DE vs WELS.DE
ESIH.DE
iShares MSCI Europe Health Care Sector UCITS ETF E...Health & Biotech Equities
15
-2.35%
—Nov 2020ZPDH.DE vs ESIH.DE
WELG.DE
Amundi S&P Global Health Care ESG UCITS ETF EUR Di...Health & Biotech Equities
16
-3.60%
—Sep 2022ZPDH.DE vs WELG.DE
XDG3.DE
Xtrackers MSCI Global SDG 3 Good Health UCITS ETF ...Health & Biotech Equities
11
-6.02%
—Jan 2023ZPDH.DE vs XDG3.DE
SC0T.DE
Invesco European Health Care Sector UCITS ETFHealth & Biotech Equities
12
-3.57%
—Jul 2009ZPDH.DE vs SC0T.DE
W311.DE
HANetf HAN-GINS Indxx Healthcare Megatrend Equal W...Health & Biotech Equities
18
-3.63%
—Apr 2019ZPDH.DE vs W311.DE
2B78.DE
iShares Healthcare Innovation UCITS ETFHealth & Biotech Equities
26
-2.07%
—Sep 2016ZPDH.DE vs 2B78.DE
EXV4.DE
iShares STOXX Europe 600 Health Care UCITS ETF (DE...Health & Biotech Equities
13
-2.60%
—Apr 2001ZPDH.DE vs EXV4.DE

Compare ZPDH.DE with Any Fund or Stock

Compare ZPDH.DE with any ETF, mutual fund, or stock using PortfoliosLab's comparison tool.

 

Diversifiers

Pair ZPDH.DE with funds that move differently

SPDR S&P US Health Care Select Sector UCITS ETF alternatives help with substitution. Diversifiers are the next step when you want funds with lower historical correlation to ZPDH.DE.

Explore ZPDH.DE Diversifiers