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SPDR S&P US Health Care Select Sector UCITS ETF (ZPDH.DE) Alternatives

ETF · Currency in EUR · Last updated Jul 16, 2026

ZPDH.DE is a passive ETF by State Street tracking the investment results of the S&P Health Care Select Sector. ZPDH.DE launched on Jul 7, 2015 and has a 0.15% expense ratio.

SPDR S&P US Health Care Select Sector UCITS ETF (ZPDH.DE) belongs to the Health & Biotech Equities category. Below you'll find alternative ETFs from the same category, ranked by key criteria, plus funds that investors commonly compare with ZPDH.DE. Use the tables to find lower-cost options, better risk-adjusted returns, or a closer substitute for your current allocation.

Cheapest Alternatives to ZPDH.DE

ZPDH.DE charges 0.15% annually. There is 1 ETF in the Health & Biotech Equities category with a lower expense ratio, going as low as 0.12%.

SymbolNameExpense RatioAUMInception
XUHC.DE
Xtrackers MSCI USA Health Care UCITS ETF 1D0.12%—Sep 2017ZPDH.DE vs XUHC.DE
QDVG.DE
iShares S&P 500 Health Care Sector UCITS ETF (Acc)0.15%—Nov 2015ZPDH.DE vs QDVG.DE
DXSE.DE
Xtrackers MSCI Europe Health Care ESG Screened UCI...0.17%—Jun 2007ZPDH.DE vs DXSE.DE
SPYH.DE
State Street SPDR MSCI Europe Health Care UCITS ET...0.18%—Dec 2014ZPDH.DE vs SPYH.DE
WELG.DE
Amundi S&P Global Health Care ESG UCITS ETF EUR Di...0.18%—Sep 2022ZPDH.DE vs WELG.DE

Best Risk-Adjusted Alternatives to ZPDH.DE

ZPDH.DE has a PortfoliosLab risk / return rank of 51. There are 10 ETFs in the Health & Biotech Equities category with higher risk-adjusted ranks, going as high as 93.

SymbolNameRisk / Return RankAUMInception
NBTK.DE
Invesco Nasdaq Biotech UCITS ETF
93
—Nov 2014ZPDH.DE vs NBTK.DE
2B70.DE
iShares Nasdaq US Biotechnology UCITS ETF
92
—Oct 2017ZPDH.DE vs 2B70.DE
2B77.DE
iShares Ageing Population UCITS ETF
87
—Sep 2016ZPDH.DE vs 2B77.DE
GN0M.DE
Global X Genomics & Biotechnology UCITS ETF
81
—Nov 2021ZPDH.DE vs GN0M.DE
WRNA.DE
WisdomTree BioRevolution UCITS ETF USD Acc
74
—Dec 2021ZPDH.DE vs WRNA.DE

Top Performing ZPDH.DE Alternatives (YTD)

ZPDH.DE is at 5.62% YTD. There are 13 ETFs in the Health & Biotech Equities category with higher YTD returns, going as high as 30.35%.

SymbolNameYTD ReturnAUMInception
WELP.DE
HANetf HAN-GINS Indxx Healthcare Megatrend Equal W...
30.35%
—Sep 2022ZPDH.DE vs WELP.DE
GN0M.DE
Global X Genomics & Biotechnology UCITS ETF
24.33%
—Nov 2021ZPDH.DE vs GN0M.DE
WRNA.DE
WisdomTree BioRevolution UCITS ETF USD Acc
22.51%
—Dec 2021ZPDH.DE vs WRNA.DE
2B70.DE
iShares Nasdaq US Biotechnology UCITS ETF
16.36%
—Oct 2017ZPDH.DE vs 2B70.DE
NBTK.DE
Invesco Nasdaq Biotech UCITS ETF
15.92%
—Nov 2014ZPDH.DE vs NBTK.DE

Lowest Volatility Alternatives to ZPDH.DE

ZPDH.DE has 15.28% 1-year volatility. There are 8 ETFs in the Health & Biotech Equities category with lower 1-year volatility, going as low as 12.26%.

SymbolNameVolatility 1YAUMInception
2B77.DE
iShares Ageing Population UCITS ETF12.26%—Sep 2016ZPDH.DE vs 2B77.DE
XDWH.DE
Xtrackers MSCI World Health Care UCITS ETF 1C14.23%—Mar 2016ZPDH.DE vs XDWH.DE
LYPE.DE
Amundi MSCI World Health Care UCITS ETF EUR Acc14.43%—Aug 2010ZPDH.DE vs LYPE.DE
CBUF.DE
iShares MSCI World Health Care Sector ESG UCITS ET...14.49%—Oct 2019ZPDH.DE vs CBUF.DE
XUHC.DE
Xtrackers MSCI USA Health Care UCITS ETF 1D15.12%—Sep 2017ZPDH.DE vs XUHC.DE

Lowest Drawdown Alternatives to ZPDH.DE

ZPDH.DE has a 1-year max drawdown of -10.79%. There are 8 ETFs in the Health & Biotech Equities category with shallower 1-year drawdowns, going as shallow as -6.24%.

SymbolNameMax Drawdown 1YAUMInception
NBTK.DE
Invesco Nasdaq Biotech UCITS ETF
-6.24%
—Nov 2014ZPDH.DE vs NBTK.DE
2B70.DE
iShares Nasdaq US Biotechnology UCITS ETF
-6.28%
—Oct 2017ZPDH.DE vs 2B70.DE
2B77.DE
iShares Ageing Population UCITS ETF
-6.76%
—Sep 2016ZPDH.DE vs 2B77.DE
ETLI.DE
L&G Pharma Breakthrough UCITS ETF
-9.04%
—Jan 2018ZPDH.DE vs ETLI.DE
XDWH.DE
Xtrackers MSCI World Health Care UCITS ETF 1C
-9.82%
—Mar 2016ZPDH.DE vs XDWH.DE

Other ETFs from State Street

The 10 most viewed State Street ETFs shown here include SPYL.DE, SPYY.DE, SPYI.DE and span 7 categories.

SymbolNameCategoryRisk / Return RankYTD ReturnAUMInception
SPYL.DE
State Street SPDR S&P 500 UCITS ETF USD Unhedged (...S&P 500, Large Cap Blend Equities
77
12.88%
—Oct 2023ZPDH.DE vs SPYL.DE
SPYY.DE
State Street SPDR MSCI All Country World UCITS ETF...Global Equities
86
14.00%
—May 2011ZPDH.DE vs SPYY.DE
SPYI.DE
SPDR MSCI ACWI IMI UCITS ETFGlobal Equities
87
14.63%
—May 2011ZPDH.DE vs SPYI.DE
ZPRV.DE
SPDR MSCI USA Small Cap Value Weighted UCITS ETFSmall Cap Value Equities
89
21.22%
—Feb 2015ZPDH.DE vs ZPRV.DE
SPPW.DE
SPDR MSCI World UCITS ETFGlobal Equities
84
12.94%
—Feb 2019ZPDH.DE vs SPPW.DE
SPY5.DE
SPDR S&P 500 UCITS ETFS&P 500
78
13.10%
—Mar 2012ZPDH.DE vs SPY5.DE
ZPRX.DE
SPDR MSCI Europe Small Cap Value Weighted UCITS ET...Europe Equities
38
9.27%
—Feb 2015ZPDH.DE vs ZPRX.DE
SPYW.DE
SPDR S&P Euro Dividend Aristocrats UCITS ETF (Dist...Europe Equities
45
9.43%
—Feb 2012ZPDH.DE vs SPYW.DE
SPYM.DE
SPDR MSCI Emerging Markets UCITS ETFEmerging Markets Equities
77
23.48%
—May 2011ZPDH.DE vs SPYM.DE
SPPY.DE
State Street SPDR S&P 500 Leaders UCITS ETFS&P 500, ESG
85
12.87%
—Dec 2019ZPDH.DE vs SPPY.DE

Often Compared With ZPDH.DE

Investors most often compare ZPDH.DE with LHTC.DE, WHEA.AS, ^GSPC. These 20 comparison targets span 5 categories, based on PortfoliosLab usage data.

SymbolNameCategoryRisk / Return RankYTD ReturnAUMInception
LHTC.DE
Lyxor STOXX Europe 600 Healthcare UCITS ETF AccHealth & Biotech Equities
25
1.10%
—Aug 2006ZPDH.DE vs LHTC.DE
WHEA.AS
State Street SPDR MSCI World Health Care UCITS ETFHealth & Biotech Equities
41
3.15%
—Apr 2016ZPDH.DE vs WHEA.AS
^GSPC
S&P 500 Index
81
10.62%
——ZPDH.DE vs ^GSPC
HWWA.L
HSBC Multi Factor Worldwide Equity UCITS ETFGlobal Equities
89
12.79%
846.89MJul 2014ZPDH.DE vs HWWA.L
VJPU.L
Vanguard FTSE Japan UCITS ETF USD Hedged AccJapan Equities, Asia Pacific Equities
92
21.68%
4.81BJan 2020ZPDH.DE vs VJPU.L
XLV
State Street Health Care Select Sector SPDR ETFHealth & Biotech Equities
48
3.13%
41.65BDec 1998ZPDH.DE vs XLV
FHLC
Fidelity MSCI Health Care Index ETFHealth & Biotech Equities
57
4.68%
3.22BOct 2013ZPDH.DE vs FHLC
EHLT.DE
Lyxor STOXX Europe 600 Healthcare UCITS ETF DistHealth & Biotech Equities
24
1.08%
—Jul 2020ZPDH.DE vs EHLT.DE
AGES.L
iShares Ageing Population UCITS ETFGlobal Equities
82
10.62%
659.26MSep 2016ZPDH.DE vs AGES.L
XGEN.DE
Xtrackers MSCI Genomic Healthcare Innovation UCITS...Health & Biotech Equities—
10.03%
—Jul 2022ZPDH.DE vs XGEN.DE
DDOC.DE
Global X Telemedicine & Digital Health UCITS ETF A...Health & Biotech Equities
20
12.40%
—Dec 2020ZPDH.DE vs DDOC.DE
ESIH.DE
iShares MSCI Europe Health Care Sector UCITS ETF E...Health & Biotech Equities
26
1.54%
—Nov 2020ZPDH.DE vs ESIH.DE
WELS.DE
Amundi S&P Global Health Care ESG UCITS ETF EUR Ac...Health & Biotech Equities
29
0.49%
—Sep 2022ZPDH.DE vs WELS.DE
PPH
VanEck Pharmaceutical ETFHealth & Biotech Equities
54
5.68%
944.89MDec 2011ZPDH.DE vs PPH
XDG3.DE
Xtrackers MSCI Global SDG 3 Good Health UCITS ETF ...Health & Biotech Equities
17
-0.67%
—Jan 2023ZPDH.DE vs XDG3.DE
SC0T.DE
Invesco European Health Care Sector UCITS ETFHealth & Biotech Equities
23
1.21%
—Jul 2009ZPDH.DE vs SC0T.DE
WH2E.DE
Invesco S&P World Health Care ESG UCITS ETF AccHealth & Biotech Equities
33
0.27%
—Apr 2023ZPDH.DE vs WH2E.DE
W311.DE
HANetf HAN-GINS Indxx Healthcare Megatrend Equal W...Health & Biotech Equities, Equal Weight
30
5.72%
—Apr 2019ZPDH.DE vs W311.DE
2B78.DE
iShares Healthcare Innovation UCITS ETFHealth & Biotech Equities
58
9.20%
—Sep 2016ZPDH.DE vs 2B78.DE
EXV4.DE
iShares STOXX Europe 600 Health Care UCITS ETF (DE...Health & Biotech Equities
25
1.24%
—Apr 2001ZPDH.DE vs EXV4.DE

Compare ZPDH.DE with Any Fund or Stock

Compare ZPDH.DE with any ETF, mutual fund, or stock using PortfoliosLab's comparison tool.

 

Diversifiers

Pair ZPDH.DE with funds that move differently

SPDR S&P US Health Care Select Sector UCITS ETF alternatives help with substitution. Diversifiers are the next step when you want funds with lower historical correlation to ZPDH.DE.

Explore ZPDH.DE Diversifiers