XBI Top Holdings & Constituents
XBI, offered by State Street, holds 158 reported positions across $11.1B in assets. Its largest holdings are State Street Global Advisors (8.01%), Apellis Pharmaceuticals Inc (APLS) (1.83%), and Alkermes PLC (1.45%). The 5 biggest positions account for 14.03% of reported assets. The table below lists every reported holding with its portfolio weight and market value in US dollars — open any constituent to research its own performance.
| Position | Weight | Market Value |
|---|---|---|
— State Street Global Advisors | 8.01% | $595.46M |
APLS Apellis Pharmaceuticals Inc | 1.83% | $136.40M |
— Alkermes PLC | 1.45% | $107.88M |
MDGL Madrigal Pharmaceuticals Inc | 1.38% | $102.81M |
TGTX TG Therapeutics Inc | 1.35% | $100.33M |
Holdings data comes from the latest SEC Form N-PORT-P filing for this fund, covering the reporting period ended Mar 31, 2026. Market values are reported in US dollars, and each weight represents the position's share of reported fund assets. Cash, derivatives, and rounding can mean displayed weights do not total 100%. Funds rebalance and file on a schedule, so this page may not reflect intraday or post-filing changes.