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NBIX vs. SPY
Performance
Risk-Adjusted Performance
Dividends
Drawdowns
Volatility

Correlation

The correlation between NBIX and SPY is 0.38, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.


-0.50.00.51.00.4

Performance

NBIX vs. SPY - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Neurocrine Biosciences, Inc. (NBIX) and SPDR S&P 500 ETF (SPY). The values are adjusted to include any dividend payments, if applicable.

-25.00%-20.00%-15.00%-10.00%-5.00%0.00%5.00%10.00%AugustSeptemberOctoberNovemberDecember2025
-1.39%
8.43%
NBIX
SPY

Key characteristics

Sharpe Ratio

NBIX:

0.14

SPY:

2.20

Sortino Ratio

NBIX:

0.39

SPY:

2.91

Omega Ratio

NBIX:

1.06

SPY:

1.41

Calmar Ratio

NBIX:

0.17

SPY:

3.35

Martin Ratio

NBIX:

0.36

SPY:

13.99

Ulcer Index

NBIX:

12.56%

SPY:

2.01%

Daily Std Dev

NBIX:

32.84%

SPY:

12.79%

Max Drawdown

NBIX:

-97.21%

SPY:

-55.19%

Current Drawdown

NBIX:

-6.46%

SPY:

-1.35%

Returns By Period

In the year-to-date period, NBIX achieves a 4.95% return, which is significantly higher than SPY's 1.96% return. Over the past 10 years, NBIX has outperformed SPY with an annualized return of 16.34%, while SPY has yielded a comparatively lower 13.29% annualized return.


NBIX

YTD

4.95%

1M

5.79%

6M

-1.39%

1Y

4.29%

5Y*

6.76%

10Y*

16.34%

SPY

YTD

1.96%

1M

1.09%

6M

8.43%

1Y

25.46%

5Y*

14.30%

10Y*

13.29%

*Annualized

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Risk-Adjusted Performance

NBIX vs. SPY — Risk-Adjusted Performance Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

NBIX
The Risk-Adjusted Performance Rank of NBIX is 4848
Overall Rank
The Sharpe Ratio Rank of NBIX is 5151
Sharpe Ratio Rank
The Sortino Ratio Rank of NBIX is 4242
Sortino Ratio Rank
The Omega Ratio Rank of NBIX is 4545
Omega Ratio Rank
The Calmar Ratio Rank of NBIX is 5454
Calmar Ratio Rank
The Martin Ratio Rank of NBIX is 5050
Martin Ratio Rank

SPY
The Risk-Adjusted Performance Rank of SPY is 8383
Overall Rank
The Sharpe Ratio Rank of SPY is 8383
Sharpe Ratio Rank
The Sortino Ratio Rank of SPY is 8080
Sortino Ratio Rank
The Omega Ratio Rank of SPY is 8383
Omega Ratio Rank
The Calmar Ratio Rank of SPY is 8383
Calmar Ratio Rank
The Martin Ratio Rank of SPY is 8585
Martin Ratio Rank
The risk-adjusted ranks indicate the investment's position relative to the market. A rank closer to 100 signifies top-performing investments, while a rank closer to 0 might suggest underperformance, based on the selected ratio. The values are calculated based on the past 12 months of returns.

NBIX vs. SPY - Risk-Adjusted Performance Comparison

This table presents a comparison of risk-adjusted performance metrics for Neurocrine Biosciences, Inc. (NBIX) and SPDR S&P 500 ETF (SPY). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.


Sharpe ratio
The chart of Sharpe ratio for NBIX, currently valued at 0.14, compared to the broader market-2.000.002.004.000.142.20
The chart of Sortino ratio for NBIX, currently valued at 0.39, compared to the broader market-4.00-2.000.002.004.006.000.392.91
The chart of Omega ratio for NBIX, currently valued at 1.06, compared to the broader market0.501.001.502.001.061.41
The chart of Calmar ratio for NBIX, currently valued at 0.17, compared to the broader market0.002.004.006.000.173.35
The chart of Martin ratio for NBIX, currently valued at 0.36, compared to the broader market-10.000.0010.0020.0030.000.3613.99
NBIX
SPY

The current NBIX Sharpe Ratio is 0.14, which is lower than the SPY Sharpe Ratio of 2.20. The chart below compares the historical Sharpe Ratios of NBIX and SPY, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.


Rolling 12-month Sharpe Ratio0.001.002.003.004.00AugustSeptemberOctoberNovemberDecember2025
0.14
2.20
NBIX
SPY

Dividends

NBIX vs. SPY - Dividend Comparison

NBIX has not paid dividends to shareholders, while SPY's dividend yield for the trailing twelve months is around 1.18%.


TTM20242023202220212020201920182017201620152014
NBIX
Neurocrine Biosciences, Inc.
0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%
SPY
SPDR S&P 500 ETF
1.18%1.21%1.40%1.65%1.20%1.52%1.75%2.04%1.80%2.03%2.06%1.87%

Drawdowns

NBIX vs. SPY - Drawdown Comparison

The maximum NBIX drawdown since its inception was -97.21%, which is greater than SPY's maximum drawdown of -55.19%. Use the drawdown chart below to compare losses from any high point for NBIX and SPY. For additional features, visit the drawdowns tool.


-25.00%-20.00%-15.00%-10.00%-5.00%0.00%AugustSeptemberOctoberNovemberDecember2025
-6.46%
-1.35%
NBIX
SPY

Volatility

NBIX vs. SPY - Volatility Comparison

Neurocrine Biosciences, Inc. (NBIX) has a higher volatility of 5.90% compared to SPDR S&P 500 ETF (SPY) at 5.10%. This indicates that NBIX's price experiences larger fluctuations and is considered to be riskier than SPY based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


0.00%5.00%10.00%15.00%20.00%25.00%AugustSeptemberOctoberNovemberDecember2025
5.90%
5.10%
NBIX
SPY
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Disclaimer

The information contained herein does not constitute investment advice and made available for educational purposes only. Prices and returns on equities are listed without consideration of fees, commissions, taxes, penalties, or interest payable due to purchasing, holding, or selling.

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