Asset Allocation
| Position | Category/Sector | Target Weight |
|---|---|---|
ARQT Arcutis Biotherapeutics, Inc. | Healthcare | 9.09% |
CRNC Cerence Inc. | Technology | 9.09% |
CRSP CRISPR Therapeutics AG | Healthcare | 9.09% |
DRUG Bright Minds Biosciences Inc | Healthcare | 9.09% |
EDIT Editas Medicine, Inc. | Healthcare | 9.09% |
NTLA Intellia Therapeutics, Inc. | Healthcare | 9.09% |
RAPT RAPT Therapeutics, Inc. | Healthcare | 9.09% |
RIGL Rigel Pharmaceuticals, Inc. | Healthcare | 9.09% |
SPRO Spero Therapeutics, Inc. | Healthcare | 9.09% |
TARS Tarsus Pharmaceuticals, Inc. | Healthcare | 9.09% |
TLSA Tiziana Life Sciences PLC | Healthcare | 9.09% |
Performance
Performance Chart
The chart shows the growth of an initial investment of $10,000 in 025 біостартапи, comparing it to the performance of the S&P 500 index or another benchmark. All prices have been adjusted for splits and dividends. The portfolio is rebalanced Every 3 months.
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The earliest data available for this chart is Mar 22, 2021, corresponding to the inception date of DRUG
Returns By Period
| 1D | 1M | YTD | 6M | 1Y | 3Y* | 5Y* | 10Y* | |
|---|---|---|---|---|---|---|---|---|
Benchmark S&P 500 Index | 0.11% | -3.43% | -3.84% | -1.98% | 16.08% | 16.86% | 10.37% | 12.29% |
Portfolio 025 біостартапи | 0.64% | -1.77% | 2.65% | 2.90% | 148.82% | 101.38% | 29.05% | — |
| Portfolio components: | ||||||||
ARQT Arcutis Biotherapeutics, Inc. | -1.95% | 0.13% | -18.63% | 11.20% | 42.35% | 28.45% | -4.50% | — |
TARS Tarsus Pharmaceuticals, Inc. | -0.14% | -8.40% | -14.36% | 19.31% | 36.18% | 77.35% | 16.32% | — |
CRNC Cerence Inc. | 7.09% | -3.59% | -32.18% | -45.49% | -13.90% | -36.26% | -40.01% | — |
SPRO Spero Therapeutics, Inc. | -0.82% | 10.96% | 4.29% | 19.70% | 244.19% | 16.93% | -29.83% | — |
TLSA Tiziana Life Sciences PLC | 0.00% | -14.38% | -16.11% | -37.50% | 12.61% | 7.19% | -14.59% | — |
DRUG Bright Minds Biosciences Inc | -0.36% | -10.68% | -8.43% | 27.61% | 102.38% | 215.40% | 21.71% | — |
NTLA Intellia Therapeutics, Inc. | -1.06% | -3.49% | 46.05% | -35.76% | 79.86% | -29.26% | -30.34% | — |
CRSP CRISPR Therapeutics AG | 1.43% | -14.73% | -5.59% | -32.01% | 44.81% | 3.02% | -16.14% | — |
EDIT Editas Medicine, Inc. | 2.30% | 30.88% | 30.24% | -31.36% | 126.27% | -27.75% | -42.59% | -23.63% |
RAPT RAPT Therapeutics, Inc. | 0.00% | 0.00% | 71.30% | 99.38% | 525.22% | -38.25% | -15.58% | — |
Monthly Returns
Based on dividend-adjusted daily data since Mar 23, 2021, 025 біостартапи's average daily return is +0.25%, while the average monthly return is +5.70%. At this rate, your investment would double in approximately 1.0 years.
Historically, 50% of months were positive and 50% were negative. The best month was Oct 2024 with a return of +337.3%, while the worst month was Jan 2022 at -20.7%. The longest winning streak lasted 8 consecutive months, and the longest losing streak was 6 months.
On a daily basis, 025 біостартапи closed higher 50% of trading days. The best single day was Oct 15, 2024 with a return of +246.0%, while the worst single day was Oct 16, 2024 at -18.8%.
| Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec | Total | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026 | 5.22% | 2.37% | -8.05% | 3.64% | 2.65% | ||||||||
| 2025 | 2.24% | 10.54% | -15.90% | 6.74% | 14.13% | 16.84% | 13.71% | 10.72% | 28.86% | 2.87% | 8.08% | -4.49% | 133.10% |
| 2024 | 8.65% | 16.01% | -9.24% | -16.04% | 2.79% | -7.78% | 9.83% | -6.01% | 1.43% | 337.25% | 0.45% | -14.65% | 257.37% |
| 2023 | 16.23% | -5.60% | -7.68% | 6.85% | 4.13% | -3.99% | 11.99% | -15.44% | -15.42% | -20.27% | 20.31% | 15.64% | -3.88% |
| 2022 | -20.70% | -10.34% | 4.35% | -20.60% | -11.77% | -2.47% | 12.52% | 11.71% | -3.06% | -8.55% | -2.54% | -7.77% | -49.23% |
| 2021 | -5.63% | -0.88% | -4.65% | 25.94% | -11.61% | 10.47% | -6.83% | -0.72% | -16.93% | -3.20% | -18.41% |
Benchmark Metrics
Portfolio has an annualized alpha of 64.74%, beta of 1.23, and R² of 0.03 versus S&P 500 Index. Calculated based on daily prices since March 23, 2021.
- This portfolio captured 127.45% of S&P 500 Index gains but only 57.51% of its losses — a favorable profile for investors.
- R² of 0.03 means this portfolio moves largely independently of S&P 500 Index — capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.
- Alpha
- 64.74%
- Beta
- 1.23
- R²
- 0.03
- Upside Capture
- 127.45%
- Downside Capture
- 57.51%
Expense Ratio
025 біостартапи has an expense ratio of 0.00%, meaning no management fees are charged. Below, you can find the expense ratios of the portfolio's funds side by side and easily compare their relative costs.
Return for Risk
Risk / Return Rank
025 біостартапи ranks 97 for risk / return — in the top 97% of portfolios on our site. This means strong returns relative to risk — exactly what professional investors look for. Well-suited for investors who want to maximize return per unit of risk.
Return / Risk — by metrics
| Portfolio | Benchmark | Difference | |
|---|---|---|---|
Sharpe ratioReturn per unit of total volatility | 3.20 | 0.88 | +2.32 |
Sortino ratioReturn per unit of downside risk | 3.76 | 1.37 | +2.40 |
Omega ratioGain probability vs. loss probability | 1.45 | 1.21 | +0.25 |
Calmar ratioReturn relative to maximum drawdown | 8.15 | 1.39 | +6.76 |
Martin ratioReturn relative to average drawdown | 20.78 | 6.43 | +14.35 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
How much return does each position deliver for the risk it carries? Higher values mean better reward for the risk taken.
| Risk / Return Rank | Sharpe ratio | Sortino ratio | Omega ratio | Calmar ratio | Martin ratio | |
|---|---|---|---|---|---|---|
ARQT Arcutis Biotherapeutics, Inc. | 67 | 0.72 | 1.48 | 1.17 | 1.81 | 4.21 |
TARS Tarsus Pharmaceuticals, Inc. | 66 | 0.81 | 1.47 | 1.17 | 1.65 | 3.24 |
CRNC Cerence Inc. | 36 | -0.15 | 0.46 | 1.05 | -0.15 | -0.34 |
SPRO Spero Therapeutics, Inc. | 91 | 0.98 | 6.46 | 1.81 | 6.28 | 10.97 |
TLSA Tiziana Life Sciences PLC | 47 | 0.14 | 0.95 | 1.10 | 0.34 | 0.62 |
DRUG Bright Minds Biosciences Inc | 80 | 1.39 | 2.28 | 1.25 | 2.87 | 6.35 |
NTLA Intellia Therapeutics, Inc. | 67 | 0.80 | 1.59 | 1.23 | 1.37 | 2.43 |
CRSP CRISPR Therapeutics AG | 63 | 0.71 | 1.45 | 1.17 | 1.17 | 2.30 |
EDIT Editas Medicine, Inc. | 77 | 1.29 | 2.27 | 1.26 | 2.28 | 4.31 |
RAPT RAPT Therapeutics, Inc. | 98 | 4.73 | 4.47 | 1.59 | 11.35 | 25.83 |
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Dividends
Dividend yield
Drawdowns
Drawdowns Chart
The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.
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Worst Drawdowns
The table below displays the maximum drawdowns of the 025 біостартапи. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.
The maximum drawdown for the 025 біостартапи was 76.50%, occurring on Oct 27, 2023. Recovery took 242 trading sessions.
The current 025 біостартапи drawdown is 12.17%.
Depth | Start | To Bottom | Bottom | To Recover | End | Total |
|---|---|---|---|---|---|---|
| -76.5% | Sep 3, 2021 | 541 | Oct 27, 2023 | 242 | Oct 15, 2024 | 783 |
| -41.91% | Nov 7, 2024 | 103 | Apr 8, 2025 | 58 | Jul 2, 2025 | 161 |
| -33.16% | Oct 16, 2024 | 2 | Oct 17, 2024 | 1 | Oct 18, 2024 | 3 |
| -19.63% | Jan 23, 2026 | 46 | Mar 30, 2026 | — | — | — |
| -18.74% | Mar 23, 2021 | 37 | May 13, 2021 | 21 | Jun 14, 2021 | 58 |
Volatility
Volatility Chart
The chart below shows the rolling one-month volatility.
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Diversification
Diversification Metrics
Number of Effective Assets
The portfolio contains 11 assets, with an effective number of assets of 11.00, reflecting the diversification based on asset allocation. This number of effective assets suggests that the portfolio's investments are spread across a variety of assets, indicating a well-diversified allocation. However, true diversification also depends on the correlations between assets.
Asset Correlations Table
| Benchmark | TLSA | DRUG | SPRO | TARS | ARQT | CRNC | RIGL | RAPT | EDIT | CRSP | NTLA | Portfolio | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Benchmark | 1.00 | 0.14 | 0.21 | 0.27 | 0.31 | 0.30 | 0.50 | 0.32 | 0.35 | 0.41 | 0.45 | 0.47 | 0.48 |
| TLSA | 0.14 | 1.00 | 0.07 | 0.05 | 0.09 | 0.07 | 0.11 | 0.10 | 0.13 | 0.15 | 0.16 | 0.14 | 0.33 |
| DRUG | 0.21 | 0.07 | 1.00 | 0.09 | 0.12 | 0.12 | 0.15 | 0.11 | 0.15 | 0.15 | 0.17 | 0.14 | 0.40 |
| SPRO | 0.27 | 0.05 | 0.09 | 1.00 | 0.19 | 0.26 | 0.22 | 0.26 | 0.26 | 0.34 | 0.31 | 0.33 | 0.44 |
| TARS | 0.31 | 0.09 | 0.12 | 0.19 | 1.00 | 0.29 | 0.25 | 0.28 | 0.32 | 0.34 | 0.35 | 0.35 | 0.47 |
| ARQT | 0.30 | 0.07 | 0.12 | 0.26 | 0.29 | 1.00 | 0.25 | 0.34 | 0.34 | 0.39 | 0.38 | 0.39 | 0.51 |
| CRNC | 0.50 | 0.11 | 0.15 | 0.22 | 0.25 | 0.25 | 1.00 | 0.26 | 0.30 | 0.38 | 0.39 | 0.40 | 0.49 |
| RIGL | 0.32 | 0.10 | 0.11 | 0.26 | 0.28 | 0.34 | 0.26 | 1.00 | 0.32 | 0.42 | 0.40 | 0.41 | 0.54 |
| RAPT | 0.35 | 0.13 | 0.15 | 0.26 | 0.32 | 0.34 | 0.30 | 0.32 | 1.00 | 0.44 | 0.45 | 0.44 | 0.59 |
| EDIT | 0.41 | 0.15 | 0.15 | 0.34 | 0.34 | 0.39 | 0.38 | 0.42 | 0.44 | 1.00 | 0.71 | 0.72 | 0.71 |
| CRSP | 0.45 | 0.16 | 0.17 | 0.31 | 0.35 | 0.38 | 0.39 | 0.40 | 0.45 | 0.71 | 1.00 | 0.73 | 0.69 |
| NTLA | 0.47 | 0.14 | 0.14 | 0.33 | 0.35 | 0.39 | 0.40 | 0.41 | 0.44 | 0.72 | 0.73 | 1.00 | 0.69 |
| Portfolio | 0.48 | 0.33 | 0.40 | 0.44 | 0.47 | 0.51 | 0.49 | 0.54 | 0.59 | 0.71 | 0.69 | 0.69 | 1.00 |