XHE vs. CNCR

Last updated Jun 23, 2026

XHE (SPDR S&P Health Care Equipment ETF) and CNCR (Loncar Cancer Immunotherapy ETF) are both Health & Biotech Equities funds - XHE tracks the S&P Health Care Equipment Select Industry Index while CNCR tracks the Loncar Cancer Immunotherapy Index. Both are passively managed. XHE charges 0.35%/yr vs 0.79%/yr for CNCR.

Performance

XHE vs. CNCR - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in SPDR S&P Health Care Equipment ETF (XHE) and Loncar Cancer Immunotherapy ETF (CNCR). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

XHE

• 1D: -2.39%
• 1M: -0.92%
• YTD: -8.91%
• 6M: -10.99%
• 1Y: 1.37%
• 3Y*: -5.83%
• 5Y*: -8.97%
• 10Y*: 6.02%

CNCR

• 1D: 0.00%
• 1M: 0.00%
• YTD: —
• 6M: —
• 1Y: —
• 3Y*: —
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

XHE vs. CNCR - Yearly Performance Comparison

	2026 (YTD)
XHE SPDR S&P Health Care Equipment ETF	-4.50%
CNCR Loncar Cancer Immunotherapy ETF	0.00%

XHE vs. CNCR - Sectors Allocation Comparison

Sectors	XHE	CNCR
Healthcare	98.2%	96.6%
Financial Services	1.8%	3.3%
Industrials	1.7%	-
Communication Services	1.4%	-
Basic Materials	-	-
Consumer Cyclical	-	-
Consumer Defensive	-	-
Energy	-	-
Real Estate	-	-
Technology	-	-
Utilities	-	-

Return for Risk

XHE vs. CNCR — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

XHE

XHE Risk / Return Rank: 9
XHE Sharpe Ratio Rank: 9
XHE Sortino Ratio Rank: 9
XHE Omega Ratio Rank: 9
XHE Calmar Ratio Rank: 9
XHE Martin Ratio Rank: 9

CNCR

Risk / return metrics aren't available yet — we need at least 12 months of trading data to calculate them.

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

XHE vs. CNCR - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for SPDR S&P Health Care Equipment ETF (XHE) and Loncar Cancer Immunotherapy ETF (CNCR). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	XHE	CNCR	Difference
Sharpe ratio: Return per unit of total volatility	0.06	—	—
Sortino ratio: Return per unit of downside risk	0.25	—	—
Omega ratio: Gain probability vs. loss probability	1.03	—	—
Calmar ratio: Return relative to maximum drawdown	0.08	—	—
Martin ratio: Return relative to average drawdown	0.16	—	—

Drawdowns

XHE vs. CNCR - Drawdown Comparison

The maximum XHE drawdown since its inception was -49.92%, which is greater than CNCR's maximum drawdown of 0.00%. Use the drawdown chart below to compare losses from any high point for XHE and CNCR.

Drawdown Indicators

	XHE	CNCR	Difference
Max Drawdown Largest peak-to-trough decline	-49.92%	0.00%	-49.92%
Max Drawdown (1Y) Largest decline over 1 year	-18.29%	—	—
Max Drawdown (3Y) Largest decline over 3 years	-32.62%	—	—
Max Drawdown (5Y) Largest decline over 5 years	-49.92%	—	—
Max Drawdown (10Y) Largest decline over 10 years	-49.92%	—	—
Current Drawdown Current decline from peak	-39.61%	0.00%	-39.61%
Average Drawdown Average peak-to-trough decline	-13.34%	0.00%	-13.34%
Ulcer Index Depth and duration of drawdowns from previous peaks	8.42%	—	—

Volatility

Volatility by Period

	XHE	CNCR	Difference
Volatility (1M) Calculated over the trailing 1-month period	7.40%	—	—
Volatility (6M) Calculated over the trailing 6-month period	16.50%	—	—
Volatility (1Y) Calculated over the trailing 1-year period	22.12%	0.00%	+22.12%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	24.56%	0.00%	+24.56%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	23.00%	0.00%	+23.00%

XHE vs. CNCR - Expense Ratio Comparison

XHE has a 0.35% expense ratio, which is lower than CNCR's 0.79% expense ratio.

Dividends

XHE vs. CNCR - Dividend Comparison

XHE's dividend yield for the trailing twelve months is around 0.09%, while CNCR has not paid dividends to shareholders.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
CNCR Loncar Cancer Immunotherapy ETF	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
XHE SPDR S&P Health Care Equipment ETF	0.06%	0.08%	0.04%	0.03%	0.04%	0.00%	0.00%	0.05%	0.09%	0.78%	0.17%	7.22%

Frequently Asked Questions

Which ETF is better, XHE or CNCR?

On fees, XHE is cheaper at 0.35% per year. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF is cheaper, XHE or CNCR?

XHE is cheaper with a 0.35% expense ratio, compared with 0.79% for CNCR.

Which ETF pays a higher dividend yield, XHE or CNCR?

XHE has the higher dividend yield at 0.09%, compared with 0.00% for CNCR.

What is the main difference between XHE and CNCR?

XHE tracks S&P Health Care Equipment Select Industry Index, while CNCR tracks Loncar Cancer Immunotherapy Index. They also come from different issuers: State Street and Exchange Traded Concepts. Their fees differ too: 0.35% for XHE and 0.79% for CNCR.