WDNA vs. GSKH

Last updated Jun 24, 2026

WDNA (WisdomTree BioRevolution Fund) and GSKH (GSK plc ADRhedged ETF) are both Health & Biotech Equities funds - WDNA tracks the WisdomTree BioRevolution Index while GSKH tracks the GSK plc Local Shares Total Return. Both are passively managed. Over the past year, WDNA returned 50.90% vs 42.66% for GSKH. At a 0.32 correlation, their price movements are largely independent. WDNA charges 0.45%/yr vs 0.19%/yr for GSKH.

Performance

WDNA vs. GSKH - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in WisdomTree BioRevolution Fund (WDNA) and GSK plc ADRhedged ETF (GSKH). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, WDNA achieves a 13.32% return, which is significantly higher than GSKH's 9.90% return.

WDNA

• 1D: 0.49%
• 1M: 8.93%
• YTD: 13.32%
• 6M: 11.11%
• 1Y: 50.90%
• 3Y*: 5.47%
• 5Y*: -5.03%
• 10Y*: —

GSKH

• 1D: 2.87%
• 1M: 2.94%
• YTD: 9.90%
• 6M: 10.56%
• 1Y: 42.66%
• 3Y*: —
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

WDNA vs. GSKH - Yearly Performance Comparison

	2026 (YTD)	2025
WDNA WisdomTree BioRevolution Fund	13.32%	18.90%
GSKH GSK plc ADRhedged ETF	9.90%	36.51%

Correlation

The correlation between WDNA and GSKH is 0.33, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.33
Correlation (All Time) Calculated using the full available price history since Jan 7, 2025	0.32

Return for Risk

WDNA vs. GSKH — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

WDNA

WDNA Risk / Return Rank: 66
WDNA Sharpe Ratio Rank: 65
WDNA Sortino Ratio Rank: 66
WDNA Omega Ratio Rank: 56
WDNA Calmar Ratio Rank: 85
WDNA Martin Ratio Rank: 59

GSKH

GSKH Risk / Return Rank: 51
GSKH Sharpe Ratio Rank: 53
GSKH Sortino Ratio Rank: 56
GSKH Omega Ratio Rank: 54
GSKH Calmar Ratio Rank: 51
GSKH Martin Ratio Rank: 41

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

WDNA vs. GSKH - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for WisdomTree BioRevolution Fund (WDNA) and GSK plc ADRhedged ETF (GSKH). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	WDNA	GSKH	Difference
Sharpe ratio: Return per unit of total volatility	1.98	1.64	+0.34
Sortino ratio: Return per unit of downside risk	2.81	2.43	+0.38
Omega ratio: Gain probability vs. loss probability	1.32	1.30	+0.02
Calmar ratio: Return relative to maximum drawdown	4.37	2.31	+2.06
Martin ratio: Return relative to average drawdown	9.80	6.06	+3.74

WDNA vs. GSKH - Sharpe Ratio Comparison

The current WDNA Sharpe Ratio is 1.98, which is comparable to the GSKH Sharpe Ratio of 1.64. The chart below compares the historical Sharpe Ratios of WDNA and GSKH, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

WDNA vs. GSKH - Drawdown Comparison

The maximum WDNA drawdown since its inception was -58.87%, which is greater than GSKH's maximum drawdown of -18.54%. Use the drawdown chart below to compare losses from any high point for WDNA and GSKH.

Drawdown Indicators

	WDNA	GSKH	Difference
Max Drawdown Largest peak-to-trough decline	-58.87%	-18.54%	-40.33%
Max Drawdown (1Y) Largest decline over 1 year	-11.70%	-18.54%	+6.84%
Max Drawdown (3Y) Largest decline over 3 years	-38.25%	—	—
Max Drawdown (5Y) Largest decline over 5 years	-58.87%	—	—
Current Drawdown Current decline from peak	-27.05%	-11.62%	-15.43%
Average Drawdown Average peak-to-trough decline	-35.56%	-5.86%	-29.70%
Ulcer Index Depth and duration of drawdowns from previous peaks	5.21%	7.06%	-1.85%

Volatility

WDNA vs. GSKH - Volatility Comparison

WisdomTree BioRevolution Fund (WDNA) has a higher volatility of 7.39% compared to GSK plc ADRhedged ETF (GSKH) at 6.89%. This indicates that WDNA's price experiences larger fluctuations and is considered to be riskier than GSKH based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	WDNA	GSKH	Difference
Volatility (1M) Calculated over the trailing 1-month period	7.39%	6.89%	+0.50%
Volatility (6M) Calculated over the trailing 6-month period	16.98%	18.67%	-1.69%
Volatility (1Y) Calculated over the trailing 1-year period	25.90%	26.14%	-0.24%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	25.14%	26.95%	-1.81%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	25.06%	26.95%	-1.89%

WDNA vs. GSKH - Expense Ratio Comparison

WDNA has a 0.45% expense ratio, which is higher than GSKH's 0.19% expense ratio.

Dividends

WDNA vs. GSKH - Dividend Comparison

WDNA's dividend yield for the trailing twelve months is around 4.03%, more than GSKH's 2.82% yield.

Position	TTM	2025	2024	2023	2022	2021
GSKH GSK plc ADRhedged ETF	2.82%	1.15%	0.00%	0.00%	0.00%	0.00%
WDNA WisdomTree BioRevolution Fund	4.03%	4.57%	0.75%	0.80%	0.38%	0.10%

Frequently Asked Questions

Can I hold both WDNA and GSKH in my portfolio?

WDNA and GSKH have a correlation of 0.33, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, WDNA or GSKH?

WDNA has higher volatility (7.39%) compared to GSKH (6.89%). In terms of maximum drawdown, WDNA dropped -58.87% vs GSKH's -18.54%.

Which ETF is better, WDNA or GSKH?

On 1-year performance, WDNA leads with 50.90% vs 42.66% for GSKH. On fees, GSKH is cheaper at 0.19% per year. On volatility, GSKH has been the lower-risk option at 6.89%. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF has performed better, WDNA or GSKH?

Over the 1-year period, WDNA has performed better with a 50.90% return vs 42.66%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.

Which ETF is cheaper, WDNA or GSKH?

GSKH is cheaper with a 0.19% expense ratio, compared with 0.45% for WDNA.

Which ETF pays a higher dividend yield, WDNA or GSKH?

WDNA has the higher dividend yield at 4.03%, compared with 2.82% for GSKH.

What is the main difference between WDNA and GSKH?

WDNA tracks WisdomTree BioRevolution Index, while GSKH tracks GSK plc Local Shares Total Return. They also come from different issuers: WisdomTree and ADRhedged. Their fees differ too: 0.45% for WDNA and 0.19% for GSKH.

Which has better risk-adjusted returns?

WDNA currently has the higher Sharpe Ratio (1.98 vs 1.64), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.