VHT vs. IDNA

Last updated Jun 4, 2026

VHT (Vanguard Health Care ETF) and IDNA (iShares Genomics Immunology and Healthcare ETF Genomics Immunology and Healthcare Fund) are both Health & Biotech Equities funds - VHT tracks the MSCI US Investable Market Health Care 25/50 Index while IDNA tracks the NYSE FactSet Global Genomics and Immuno Biopharma Index. Both are passively managed. Over the past 5 years, VHT returned 4.51%/yr vs -8.42%/yr for IDNA. A 0.67 correlation means they provide meaningful diversification when combined. VHT charges 0.10%/yr vs 0.47%/yr for IDNA.

Performance

VHT vs. IDNA - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Vanguard Health Care ETF (VHT) and iShares Genomics Immunology and Healthcare ETF Genomics Immunology and Healthcare Fund (IDNA). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, VHT achieves a -4.02% return, which is significantly lower than IDNA's 10.31% return.

VHT

• 1D: 0.84%
• 1M: 1.45%
• YTD: -4.02%
• 6M: -4.15%
• 1Y: 14.34%
• 3Y*: 6.14%
• 5Y*: 4.51%
• 10Y*: 9.26%

IDNA

• 1D: 0.73%
• 1M: -2.56%
• YTD: 10.31%
• 6M: 8.52%
• 1Y: 40.87%
• 3Y*: 6.74%
• 5Y*: -8.42%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

VHT vs. IDNA - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019
VHT Vanguard Health Care ETF	-4.02%	15.46%	2.66%	2.52%	-5.60%	20.57%	18.29%	13.45%
IDNA iShares Genomics Immunology and Healthcare ETF Genomics Immunology and Healthcare Fund	10.31%	17.26%	-0.72%	-7.63%	-42.28%	-3.98%	54.30%	20.83%

Correlation

The correlation between VHT and IDNA is 0.68, which is moderate. They share some common price drivers but move independently often enough to provide real diversification benefit when combined.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.68
Correlation (3Y) Calculated over the trailing 3-year period	0.64
Correlation (5Y) Calculated over the trailing 5-year period	0.66
Correlation (All Time) Calculated using the full available price history since Jun 14, 2019	0.67

The correlation between VHT and IDNA has been stable across timeframes, ranging from 0.64 to 0.68 - a consistent structural relationship.

VHT vs. IDNA - Sectors Allocation Comparison

Sectors	VHT	IDNA
Healthcare	100.0%	97.8%
Financial Services	0.0%	-
Industrials	0.0%	0.4%
Technology	0.0%	-
Basic Materials	-	-
Communication Services	-	-
Consumer Cyclical	-	-
Consumer Defensive	-	-
Energy	-	-
Real Estate	-	-
Utilities	-	-

Return for Risk

VHT vs. IDNA — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

VHT

VHT Risk / Return Rank: 27
VHT Sharpe Ratio Rank: 27
VHT Sortino Ratio Rank: 28
VHT Omega Ratio Rank: 26
VHT Calmar Ratio Rank: 28
VHT Martin Ratio Rank: 25

IDNA

IDNA Risk / Return Rank: 55
IDNA Sharpe Ratio Rank: 48
IDNA Sortino Ratio Rank: 49
IDNA Omega Ratio Rank: 42
IDNA Calmar Ratio Rank: 76
IDNA Martin Ratio Rank: 61

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

VHT vs. IDNA - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Vanguard Health Care ETF (VHT) and iShares Genomics Immunology and Healthcare ETF Genomics Immunology and Healthcare Fund (IDNA). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	VHT	IDNA	Difference
Sharpe ratio: Return per unit of total volatility	1.00	1.68	-0.67
Sortino ratio: Return per unit of downside risk	1.57	2.44	-0.87
Omega ratio: Gain probability vs. loss probability	1.18	1.27	-0.10
Calmar ratio: Return relative to maximum drawdown	1.38	3.85	-2.47
Martin ratio: Return relative to average drawdown	3.47	10.98	-7.51
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

VHT vs. IDNA - Sharpe Ratio Comparison

The current VHT Sharpe Ratio is 1.00, which is lower than the IDNA Sharpe Ratio of 1.68. The chart below compares the historical Sharpe Ratios of VHT and IDNA, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	VHT	IDNA	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.00	1.68	-0.67
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.30	-0.30	+0.60
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.55	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	0.56	0.10	+0.46

Drawdowns

VHT vs. IDNA - Drawdown Comparison

The maximum VHT drawdown since its inception was -39.12%, smaller than the maximum IDNA drawdown of -68.26%. Use the drawdown chart below to compare losses from any high point for VHT and IDNA.

Drawdown Indicators

	VHT	IDNA	Difference
Max Drawdown Largest peak-to-trough decline	-39.12%	-68.26%	+29.14%
Max Drawdown (1Y) Largest decline over 1 year	-10.40%	-10.66%	+0.26%
Max Drawdown (3Y) Largest decline over 3 years	-16.91%	-29.73%	+12.82%
Max Drawdown (5Y) Largest decline over 5 years	-17.71%	-68.26%	+50.55%
Max Drawdown (10Y) Largest decline over 10 years	-28.85%	—	—
Current Drawdown Current decline from peak	-7.05%	-45.61%	+38.56%
Average Drawdown Average peak-to-trough decline	-5.99%	-36.24%	+30.25%
Ulcer Index Depth and duration of drawdowns from previous peaks	4.14%	3.73%	+0.41%

Volatility

VHT vs. IDNA - Volatility Comparison

The current volatility for Vanguard Health Care ETF (VHT) is 4.08%, while iShares Genomics Immunology and Healthcare ETF Genomics Immunology and Healthcare Fund (IDNA) has a volatility of 7.18%. This indicates that VHT experiences smaller price fluctuations and is considered to be less risky than IDNA based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	VHT	IDNA	Difference
Volatility (1M) Calculated over the trailing 1-month period	4.08%	7.18%	-3.10%
Volatility (6M) Calculated over the trailing 6-month period	10.08%	17.98%	-7.90%
Volatility (1Y) Calculated over the trailing 1-year period	14.34%	24.48%	-10.14%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	14.96%	28.42%	-13.46%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	16.94%	29.53%	-12.59%

VHT vs. IDNA - Expense Ratio Comparison

VHT has a 0.10% expense ratio, which is lower than IDNA's 0.47% expense ratio.

Dividends

VHT vs. IDNA - Dividend Comparison

VHT's dividend yield for the trailing twelve months is around 1.71%, more than IDNA's 1.07% yield.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
IDNA iShares Genomics Immunology and Healthcare ETF Genomics Immunology and Healthcare Fund	1.07%	1.18%	0.98%	1.04%	0.54%	0.70%	0.26%	0.80%	0.00%	0.00%	0.00%	0.00%
VHT Vanguard Health Care ETF	1.71%	1.61%	1.53%	1.36%	1.33%	1.14%	1.21%	1.89%	1.38%	1.31%	1.45%	1.22%

Frequently Asked Questions

Can I hold both VHT and IDNA in my portfolio?

VHT and IDNA have a correlation of 0.68, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, VHT or IDNA?

IDNA has higher volatility (7.18%) compared to VHT (4.08%). In terms of maximum drawdown, VHT dropped -39.12% vs IDNA's -68.26%.

Which ETF is better, VHT or IDNA?

On 5-year performance, VHT leads with 4.51% vs -8.42% for IDNA. On fees, VHT is cheaper at 0.10% per year. On volatility, VHT has been the lower-risk option at 4.08%. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF has performed better, VHT or IDNA?

Over the 5-year period, VHT has performed better with a 4.51% return vs -8.42%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.

Which ETF is cheaper, VHT or IDNA?

VHT is cheaper with a 0.10% expense ratio, compared with 0.47% for IDNA.

Which ETF pays a higher dividend yield, VHT or IDNA?

VHT has the higher dividend yield at 1.71%, compared with 1.07% for IDNA.

What is the main difference between VHT and IDNA?

VHT tracks MSCI US Investable Market Health Care 25/50 Index, while IDNA tracks NYSE FactSet Global Genomics and Immuno Biopharma Index. They also come from different issuers: Vanguard and iShares. Their fees differ too: 0.10% for VHT and 0.47% for IDNA.

Which has better risk-adjusted returns?

IDNA currently has the higher Sharpe Ratio (1.68 vs 1.00), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.