UUUG vs. PILL

Last updated Jul 17, 2026

UUUG (Leverage Shares 2X Long UUUU Daily ETF) and PILL (Direxion Daily Pharmaceutical & Medical Bull 3X Shares) are both Leveraged Equities funds - UUUG tracks the Energy Fuels Inc. (UUUU) while PILL tracks the Dynamic Pharmaceuticals Intellidex Index. Both are passively managed. At a 0.28 correlation, their price movements are largely independent. UUUG charges 0.75%/yr vs 0.98%/yr for PILL.

Performance

UUUG vs. PILL - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Leverage Shares 2X Long UUUU Daily ETF (UUUG) and Direxion Daily Pharmaceutical & Medical Bull 3X Shares (PILL). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

UUUG

• 1D: -15.47%
• 1M: -44.54%
• 6M: -81.08%
• YTD: —
• 1Y: —
• 3Y*: —
• 5Y*: —
• 10Y*: —

PILL

• 1D: -2.74%
• 1M: 36.93%
• 6M: 52.58%
• YTD: 50.23%
• 1Y: 218.71%
• 3Y*: 32.71%
• 5Y*: -1.10%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

UUUG vs. PILL - Yearly Performance Comparison

	2026 (YTD)
UUUG Leverage Shares 2X Long UUUU Daily ETF	-78.58%
PILL Direxion Daily Pharmaceutical & Medical Bull 3X Shares	54.89%

Correlation

The correlation between UUUG and PILL is 0.28, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (All Time) Calculated using the full available price history since Jan 13, 2026	0.28

Return for Risk

UUUG vs. PILL — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

UUUG

Risk / return metrics aren't available yet — we need at least 12 months of trading data to calculate them.

PILL

PILL Risk / Return Rank: 93
PILL Sharpe Ratio Rank: 97
PILL Sortino Ratio Rank: 90
PILL Omega Ratio Rank: 86
PILL Calmar Ratio Rank: 96
PILL Martin Ratio Rank: 95

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

UUUG vs. PILL - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Leverage Shares 2X Long UUUU Daily ETF (UUUG) and Direxion Daily Pharmaceutical & Medical Bull 3X Shares (PILL). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	UUUG	PILL	Difference
Sharpe ratio: Return per unit of total volatility	—	3.42	—
Sortino ratio: Return per unit of downside risk	—	3.43	—
Omega ratio: Gain probability vs. loss probability	—	1.42	—
Calmar ratio: Return relative to maximum drawdown	—	6.63	—
Martin ratio: Return relative to average drawdown	—	21.65	—

Drawdowns

UUUG vs. PILL - Drawdown Comparison

The maximum UUUG drawdown since its inception was -88.74%, roughly equal to the maximum PILL drawdown of -88.76%. Use the drawdown chart below to compare losses from any high point for UUUG and PILL.

Drawdown Indicators

	UUUG	PILL	Difference
Max Drawdown Largest peak-to-trough decline	-88.74%	-88.76%	+0.02%
Max Drawdown (1Y) Largest decline over 1 year	—	-33.21%	—
Max Drawdown (3Y) Largest decline over 3 years	—	-60.43%	—
Max Drawdown (5Y) Largest decline over 5 years	—	-83.26%	—
Current Drawdown Current decline from peak	-88.74%	-48.53%	-40.21%
Average Drawdown Average peak-to-trough decline	-57.95%	-58.46%	+0.51%
Ulcer Index Depth and duration of drawdowns from previous peaks	—	10.15%	—

Volatility

Volatility by Period

	UUUG	PILL	Difference
Volatility (1M) Calculated over the trailing 1-month period	—	21.20%	—
Volatility (6M) Calculated over the trailing 6-month period	—	50.25%	—
Volatility (1Y) Calculated over the trailing 1-year period	181.16%	64.34%	+116.82%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	181.16%	61.09%	+120.07%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	181.16%	63.94%	+117.22%

UUUG vs. PILL - Expense Ratio Comparison

UUUG has a 0.75% expense ratio, which is lower than PILL's 0.98% expense ratio.

Dividends

UUUG vs. PILL - Dividend Comparison

UUUG has not paid dividends to shareholders, while PILL's dividend yield for the trailing twelve months is around 0.37%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017
PILL Direxion Daily Pharmaceutical & Medical Bull 3X Shares	0.37%	0.69%	1.28%	1.83%	0.67%	0.00%	0.00%	0.38%	0.91%	0.10%
UUUG Leverage Shares 2X Long UUUU Daily ETF	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Frequently Asked Questions

Can I hold both UUUG and PILL in my portfolio?

UUUG and PILL have a correlation of 0.28, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which ETF is better, UUUG or PILL?

On fees, UUUG is cheaper at 0.75% per year. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF is cheaper, UUUG or PILL?

UUUG is cheaper with a 0.75% expense ratio, compared with 0.98% for PILL.

Which ETF pays a higher dividend yield, UUUG or PILL?

PILL has the higher dividend yield at 0.37%, compared with 0.00% for UUUG.

What is the main difference between UUUG and PILL?

UUUG tracks Energy Fuels Inc. (UUUU), while PILL tracks Dynamic Pharmaceuticals Intellidex Index. They also come from different issuers: Leverage Shares and Direxion. Their fees differ too: 0.75% for UUUG and 0.98% for PILL.