TXG vs. SPY
TXG (10x Genomics, Inc.) is a stock, while SPY (State Street SPDR S&P 500 ETF) is S&P 500 fund tracking the S&P 500 Index. Over the past 5 years, TXG returned -30.38%/yr vs 13.51%/yr for SPY. At a 0.44 correlation, their price movements are largely independent.
Performance
TXG vs. SPY - Performance Comparison
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Returns By Period
In the year-to-date period, TXG achieves a 101.96% return, which is significantly higher than SPY's 9.74% return.
TXG
- 1D
- -5.22%
- 1M
- 39.10%
- YTD
- 101.96%
- 6M
- 94.45%
- 1Y
- 204.72%
- 3Y*
- -15.51%
- 5Y*
- -30.38%
- 10Y*
- —
SPY
- 1D
- -0.31%
- 1M
- 0.09%
- YTD
- 9.74%
- 6M
- 9.27%
- 1Y
- 26.65%
- 3Y*
- 21.27%
- 5Y*
- 13.51%
- 10Y*
- 15.70%
TXG vs. SPY - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | |
|---|---|---|---|---|---|---|---|---|
TXG 10x Genomics, Inc. | 101.96% | 13.58% | -74.34% | 53.57% | -75.54% | 5.20% | 85.70% | 41.20% |
SPY State Street SPDR S&P 500 ETF | 9.74% | 17.72% | 24.89% | 26.18% | -18.18% | 28.73% | 18.33% | 8.22% |
Correlation
The correlation between TXG and SPY is 0.42, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.42 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.43 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.48 |
Correlation (All Time) Calculated using the full available price history since Sep 12, 2019 | 0.44 |
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Return for Risk
TXG vs. SPY — Risk / Return Rank
TXG
SPY
TXG vs. SPY - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for 10x Genomics, Inc. (TXG) and State Street SPDR S&P 500 ETF (SPY). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| TXG | SPY | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +0.83 | ||
| Sortino ratioReturn per unit of downside risk | +0.50 | ||
| Omega ratioGain probability vs. loss probability | 1.39 | 1.39 | 0.00 |
| Calmar ratioReturn relative to maximum drawdown | 7.35 | 3.01 | +4.34 |
| Martin ratioReturn relative to average drawdown | 16.73 | 13.54 | +3.19 |
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Drawdowns
TXG vs. SPY - Drawdown Comparison
The maximum TXG drawdown since its inception was -96.47%, which is greater than SPY's maximum drawdown of -55.19%. Use the drawdown chart below to compare losses from any high point for TXG and SPY.
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Drawdown Indicators
| TXG | SPY | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -96.47% | -55.19% | -41.28% |
Max Drawdown (1Y)Largest decline over 1 year | -28.03% | -8.88% | -19.15% |
Max Drawdown (3Y)Largest decline over 3 years | -88.66% | -18.76% | -69.90% |
Max Drawdown (5Y)Largest decline over 5 years | -96.45% | -24.50% | -71.95% |
Max Drawdown (10Y)Largest decline over 10 years | — | -33.72% | — |
Current DrawdownCurrent decline from peak | -83.72% | -1.75% | -81.97% |
Average DrawdownAverage peak-to-trough decline | -59.78% | -9.04% | -50.74% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 12.29% | 1.97% | +10.32% |
Volatility
TXG vs. SPY - Volatility Comparison
10x Genomics, Inc. (TXG) has a higher volatility of 23.47% compared to State Street SPDR S&P 500 ETF (SPY) at 4.64%. This indicates that TXG's price experiences larger fluctuations and is considered to be riskier than SPY based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| TXG | SPY | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 23.47% | 4.64% | +18.83% |
Volatility (6M)Calculated over the trailing 6-month period | 48.22% | 9.75% | +38.47% |
Volatility (1Y)Calculated over the trailing 1-year period | 69.06% | 12.43% | +56.63% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 68.74% | 17.14% | +51.60% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 66.90% | 17.99% | +48.91% |
Dividends
TXG vs. SPY - Dividend Comparison
TXG has not paid dividends to shareholders, while SPY's dividend yield for the trailing twelve months is around 1.01%.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
SPY State Street SPDR S&P 500 ETF | 1.01% | 1.07% | 1.21% | 1.40% | 1.65% | 1.20% | 1.52% | 1.75% | 2.04% | 1.80% | 2.03% | 2.06% |
TXG 10x Genomics, Inc. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
Frequently Asked Questions
TXG and SPY have a correlation of 0.42, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
TXG has higher volatility (23.47%) compared to SPY (4.64%). In terms of maximum drawdown, TXG dropped -96.47% vs SPY's -55.19%.
TXG currently has the higher Sharpe Ratio (2.99 vs 2.16), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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