TNXP vs. VOO
Compare and contrast key facts about Tonix Pharmaceuticals Holding Corp. (TNXP) and Vanguard S&P 500 ETF (VOO).
VOO is a passively managed fund by Vanguard that tracks the performance of the S&P 500 Index. It was launched on Sep 7, 2010.
Performance
TNXP vs. VOO - Performance Comparison
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TNXP vs. VOO - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
TNXP Tonix Pharmaceuticals Holding Corp. | -12.42% | -52.64% | -97.44% | -83.46% | -96.59% | -47.01% | -42.31% | -94.68% | -93.62% | -26.61% |
VOO Vanguard S&P 500 ETF | -3.66% | 17.82% | 24.98% | 26.32% | -18.17% | 28.79% | 18.32% | 31.37% | -4.50% | 21.77% |
Returns By Period
In the year-to-date period, TNXP achieves a -12.42% return, which is significantly lower than VOO's -3.66% return. Over the past 10 years, TNXP has underperformed VOO with an annualized return of -84.40%, while VOO has yielded a comparatively higher 14.14% annualized return.
TNXP
- 1D
- -0.51%
- 1M
- -2.15%
- YTD
- -12.42%
- 6M
- -42.88%
- 1Y
- -21.60%
- 3Y*
- -89.50%
- 5Y*
- -88.81%
- 10Y*
- -84.40%
VOO
- 1D
- 0.79%
- 1M
- -4.29%
- YTD
- -3.66%
- 6M
- -1.41%
- 1Y
- 18.17%
- 3Y*
- 18.58%
- 5Y*
- 11.93%
- 10Y*
- 14.14%
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Return for Risk
TNXP vs. VOO — Risk / Return Rank
TNXP
VOO
TNXP vs. VOO - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Tonix Pharmaceuticals Holding Corp. (TNXP) and Vanguard S&P 500 ETF (VOO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| TNXP | VOO | Difference | |
|---|---|---|---|
Sharpe ratioReturn per unit of total volatility | -0.22 | 1.01 | -1.23 |
Sortino ratioReturn per unit of downside risk | 0.39 | 1.53 | -1.14 |
Omega ratioGain probability vs. loss probability | 1.04 | 1.23 | -0.19 |
Calmar ratioReturn relative to maximum drawdown | -0.29 | 1.55 | -1.84 |
Martin ratioReturn relative to average drawdown | -0.43 | 7.31 | -7.74 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| TNXP | VOO | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | -0.22 | 1.01 | -1.23 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | -0.66 | 0.71 | -1.37 |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | -0.60 | 0.79 | -1.39 |
Sharpe Ratio (All Time)Calculated using the full available price history | -0.58 | 0.83 | -1.41 |
Correlation
The correlation between TNXP and VOO is 0.20, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.
Dividends
TNXP vs. VOO - Dividend Comparison
TNXP has not paid dividends to shareholders, while VOO's dividend yield for the trailing twelve months is around 1.18%.
| TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
TNXP Tonix Pharmaceuticals Holding Corp. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
VOO Vanguard S&P 500 ETF | 1.18% | 1.13% | 1.24% | 1.46% | 1.69% | 1.25% | 1.54% | 1.88% | 2.06% | 1.78% | 2.02% | 2.10% |
Drawdowns
TNXP vs. VOO - Drawdown Comparison
The maximum TNXP drawdown since its inception was -100.00%, which is greater than VOO's maximum drawdown of -33.99%. Use the drawdown chart below to compare losses from any high point for TNXP and VOO.
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Drawdown Indicators
| TNXP | VOO | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -100.00% | -33.99% | -66.01% |
Max Drawdown (1Y)Largest decline over 1 year | -80.46% | -11.98% | -68.48% |
Max Drawdown (5Y)Largest decline over 5 years | -100.00% | -24.52% | -75.48% |
Max Drawdown (10Y)Largest decline over 10 years | -100.00% | -33.99% | -66.01% |
Current DrawdownCurrent decline from peak | -100.00% | -5.55% | -94.45% |
Average DrawdownAverage peak-to-trough decline | -91.05% | -3.72% | -87.33% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 55.09% | 2.55% | +52.54% |
Volatility
TNXP vs. VOO - Volatility Comparison
Tonix Pharmaceuticals Holding Corp. (TNXP) has a higher volatility of 27.68% compared to Vanguard S&P 500 ETF (VOO) at 5.34%. This indicates that TNXP's price experiences larger fluctuations and is considered to be riskier than VOO based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| TNXP | VOO | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 27.68% | 5.34% | +22.34% |
Volatility (6M)Calculated over the trailing 6-month period | 51.40% | 9.47% | +41.93% |
Volatility (1Y)Calculated over the trailing 1-year period | 99.65% | 18.11% | +81.54% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 135.80% | 16.82% | +118.98% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 141.06% | 17.99% | +123.07% |