SRRK vs. MLTX

Last updated Aug 1, 2026

SRRK (Scholar Rock Holding Corporation) and MLTX (MoonLake Immunotherapeutics) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. Over the past 5 years, SRRK returned 8.64%/yr vs 13.20%/yr for MLTX. Their 0.20 correlation means their historical movements had little consistent relationship.

Performance

SRRK vs. MLTX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Scholar Rock Holding Corporation (SRRK) and MoonLake Immunotherapeutics (MLTX). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, SRRK achieves a 7.37% return, which is significantly lower than MLTX's 39.91% return.

SRRK

• 1D: -3.46%
• 1M: -13.82%
• 6M: 6.66%
• YTD: 7.37%
• 1Y: 30.07%
• 3Y*: 90.42%
• 5Y*: 8.64%
• 10Y*: —
• ALL TIME*: 15.78%

MLTX

• 1D: -2.90%
• 1M: -2.69%
• 6M: 17.68%
• YTD: 39.91%
• 1Y: -65.15%
• 3Y*: -31.69%
• 5Y*: 13.20%
• 10Y*: —
• ALL TIME*: 10.87%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison

Position	Avg. Volume Value (2W)	Avg. Volume Value (1M)	Avg. Volume Value (3M)
MLTX MoonLake Immunotherapeutics	$16.11M	$20.69M	$21.49M
SRRK Scholar Rock Holding Corporation	$55.73M	$56.96M	$69.55M

SRRK vs. MLTX - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020
SRRK Scholar Rock Holding Corporation	7.37%	1.92%	129.89%	107.73%	-63.57%	-48.82%	233.77%
MLTX MoonLake Immunotherapeutics	39.91%	-75.66%	-10.33%	475.14%	6.17%	-13.02%	11.91%

Correlation

The correlation between SRRK and MLTX is 0.35, which is low. Their historical price movements had little consistent relationship.

	Correlation
Correlation (1Y) Focuses on recent behavior, but can change the most.	0.35
Correlation (3Y) Balances recent behavior with more history.	0.34
Correlation (5Y) Shows whether the relationship held over a longer period.	0.24
Correlation (All Time) Calculated using the full available price history since Oct 20, 2020	0.20

The correlation between SRRK and MLTX shifts across timeframes, from 0.20 (all time) to 0.35 (1 year), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap SRRK : $5.67B MLTX : $1.55B
EPS SRRK : -$3.45 MLTX : -$3.85
PB Ratio SRRK : 21.81 MLTX : 5.17
Total Revenue (TTM) SRRK : $0.00 MLTX : $0.00
Gross Profit (TTM) SRRK : -$1.27M MLTX : -$1.49M
EBITDA (TTM) SRRK : -$394.71M MLTX : -$179.84M

Return for Risk

SRRK vs. MLTX — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

SRRK

SRRK Risk / Return Rank: 63
SRRK Sharpe Ratio Rank: 60
SRRK Sortino Ratio Rank: 63
SRRK Omega Ratio Rank: 60
SRRK Calmar Ratio Rank: 64
SRRK Martin Ratio Rank: 67

MLTX

MLTX Risk / Return Rank: 35
MLTX Sharpe Ratio Rank: 20
MLTX Sortino Ratio Rank: 50
MLTX Omega Ratio Rank: 64
MLTX Calmar Ratio Rank: 17
MLTX Martin Ratio Rank: 24

The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

SRRK vs. MLTX - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Scholar Rock Holding Corporation (SRRK) and MoonLake Immunotherapeutics (MLTX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	SRRK	MLTX	Difference
Sharpe ratio: Return per unit of total volatility	0.45	-0.54	+0.99
Sortino ratio: Return per unit of downside risk	1.16	0.67	+0.49
Omega ratio: Gain probability vs. loss probability	1.14	1.16	-0.02
Calmar ratio: Return relative to maximum drawdown	0.87	-0.71	+1.58
Martin ratio: Return relative to average drawdown	2.38	-0.93	+3.31

SRRK vs. MLTX - Sharpe Ratio Comparison

The current SRRK Sharpe Ratio is 0.45, which is higher than the MLTX Sharpe Ratio of -0.54. The chart below compares the historical Sharpe Ratios of SRRK and MLTX, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

SRRK vs. MLTX - Drawdown Comparison

The maximum SRRK drawdown since its inception was -93.15%, roughly equal to the maximum MLTX drawdown of -90.22%. Use the drawdown chart below to compare losses from any high point for SRRK and MLTX.

Drawdown Indicators

	SRRK	MLTX	Difference
Max Drawdown Largest peak-to-trough decline	-93.15%	-90.22%	-2.93%
Max Drawdown (1Y) Largest decline over 1 year	-31.89%	-89.93%	+58.04%
Max Drawdown (3Y) Largest decline over 3 years	-65.21%	-90.22%	+25.01%
Max Drawdown (5Y) Largest decline over 5 years	-88.96%	-90.22%	+1.26%
Current Drawdown Current decline from peak	-30.47%	-71.12%	+40.65%
Average Drawdown Average peak-to-trough decline	-55.85%	-30.25%	-25.60%
Ulcer Index Depth and duration of drawdowns from previous peaks	11.67%	68.46%	-56.79%

Volatility

SRRK vs. MLTX - Volatility Comparison

The current volatility for Scholar Rock Holding Corporation (SRRK) is 12.80%, while MoonLake Immunotherapeutics (MLTX) has a volatility of 16.02%. This indicates that SRRK experiences smaller price fluctuations and is considered to be less risky than MLTX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	SRRK	MLTX	Difference
Volatility (1M) Calculated over the trailing 1-month period	12.80%	16.02%	-3.22%
Volatility (6M) Calculated over the trailing 6-month period	35.23%	42.92%	-7.69%
Volatility (1Y) Calculated over the trailing 1-year period	62.28%	117.23%	-54.95%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	180.10%	91.77%	+88.33%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	156.39%	85.91%	+70.48%

Dividends

SRRK vs. MLTX - Dividend Comparison

Neither SRRK nor MLTX has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both SRRK and MLTX in my portfolio?

SRRK and MLTX have a correlation of 0.35, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, SRRK or MLTX?

MLTX has higher volatility (16.02%) compared to SRRK (12.80%). In terms of maximum drawdown, SRRK dropped -93.15% vs MLTX's -90.22%.

Which has better risk-adjusted returns?

SRRK currently has the higher Sharpe Ratio (0.45 vs -0.54), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.