SRPT vs. UTHR
SRPT (Sarepta Therapeutics, Inc.) and UTHR (United Therapeutics Corporation) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. Over the past 10 years, SRPT returned 0.42%/yr vs 16.80%/yr for UTHR. At a 0.24 correlation, their price movements are largely independent.
Performance
SRPT vs. UTHR - Performance Comparison
Loading charts...
Returns By Period
In the year-to-date period, SRPT achieves a -24.54% return, which is significantly lower than UTHR's 12.77% return. Over the past 10 years, SRPT has underperformed UTHR with an annualized return of 0.42%, while UTHR has yielded a comparatively higher 16.80% annualized return.
SRPT
- 1D
- -0.06%
- 1M
- -26.32%
- YTD
- -24.54%
- 6M
- -25.64%
- 1Y
- -58.22%
- 3Y*
- -49.37%
- 5Y*
- -25.96%
- 10Y*
- 0.42%
UTHR
- 1D
- 1.74%
- 1M
- -5.46%
- YTD
- 12.77%
- 6M
- 14.24%
- 1Y
- 69.48%
- 3Y*
- 36.25%
- 5Y*
- 25.58%
- 10Y*
- 16.80%
SRPT vs. UTHR - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
SRPT Sarepta Therapeutics, Inc. | -24.54% | -82.30% | 26.09% | -25.58% | 43.90% | -47.18% | 32.12% | 18.24% | 96.14% | 102.84% |
UTHR United Therapeutics Corporation | 12.77% | 38.09% | 60.46% | -20.93% | 28.70% | 42.35% | 72.33% | -19.12% | -26.39% | 3.15% |
Correlation
The correlation between SRPT and UTHR is 0.16, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.16 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.22 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.23 |
Correlation (10Y) Calculated over the trailing 10-year period | 0.29 |
Correlation (All Time) Calculated using the full available price history since Jun 18, 1999 | 0.24 |
The correlation between SRPT and UTHR shifts across timeframes, from 0.16 (1 year) to 0.29 (10 years), reflecting how their relationship changes across market environments.
Fundamentals
SRPT:
$1.98B
UTHR:
$25.93B
SRPT:
$0.60
UTHR:
$27.00
SRPT:
27.06
UTHR:
20.35
SRPT:
0.81
UTHR:
8.26
SRPT:
1.32
UTHR:
4.39
SRPT:
$2.18B
UTHR:
$3.17B
SRPT:
$751.34M
UTHR:
$2.74B
SRPT:
$107.91M
UTHR:
$1.75B
Compare stocks, funds, or ETFs
Search for stocks, ETFs, and funds for a quick comparison or use the comparison tool for more options.
Return for Risk
SRPT vs. UTHR — Risk / Return Rank
SRPT
UTHR
SRPT vs. UTHR - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Sarepta Therapeutics, Inc. (SRPT) and United Therapeutics Corporation (UTHR). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| SRPT | UTHR | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -1.97 | ||
| Sortino ratioReturn per unit of downside risk | -3.17 | ||
| Omega ratioGain probability vs. loss probability | 0.94 | 1.38 | -0.44 |
| Calmar ratioReturn relative to maximum drawdown | -0.81 | 4.27 | -5.08 |
| Martin ratioReturn relative to average drawdown | -1.08 | 11.01 | -12.09 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
Loading charts...
Sharpe Ratios by Period
| SRPT | UTHR | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | -0.56 | 1.40 | -1.97 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | -0.37 | 0.73 | -1.10 |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | 0.01 | 0.48 | -0.47 |
Sharpe Ratio (All Time)Calculated using the full available price history | -0.03 | 0.38 | -0.42 |
Drawdowns
SRPT vs. UTHR - Drawdown Comparison
The maximum SRPT drawdown since its inception was -98.17%, which is greater than UTHR's maximum drawdown of -93.18%. Use the drawdown chart below to compare losses from any high point for SRPT and UTHR.
Loading charts...
Drawdown Indicators
| SRPT | UTHR | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -98.17% | -93.18% | -4.99% |
Max Drawdown (1Y)Largest decline over 1 year | -72.26% | -16.35% | -55.91% |
Max Drawdown (3Y)Largest decline over 3 years | -92.72% | -33.00% | -59.72% |
Max Drawdown (5Y)Largest decline over 5 years | -92.72% | -33.00% | -59.72% |
Max Drawdown (10Y)Largest decline over 10 years | -93.33% | -55.56% | -37.77% |
Current DrawdownCurrent decline from peak | -90.91% | -7.92% | -82.99% |
Average DrawdownAverage peak-to-trough decline | -68.14% | -35.32% | -32.82% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 54.00% | 6.33% | +47.67% |
Volatility
SRPT vs. UTHR - Volatility Comparison
Sarepta Therapeutics, Inc. (SRPT) has a higher volatility of 17.02% compared to United Therapeutics Corporation (UTHR) at 8.33%. This indicates that SRPT's price experiences larger fluctuations and is considered to be riskier than UTHR based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
Loading charts...
Volatility by Period
| SRPT | UTHR | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 17.02% | 8.33% | +8.69% |
Volatility (6M)Calculated over the trailing 6-month period | 52.59% | 26.06% | +26.53% |
Volatility (1Y)Calculated over the trailing 1-year period | 103.50% | 49.78% | +53.72% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 69.81% | 35.15% | +34.66% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 70.75% | 35.10% | +35.65% |
Dividends
SRPT vs. UTHR - Dividend Comparison
Neither SRPT nor UTHR has paid dividends to shareholders.
Financials
SRPT vs. UTHR - Financials Comparison
This section allows you to compare key financial metrics between Sarepta Therapeutics, Inc. and United Therapeutics Corporation. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
SRPT vs. UTHR - Profitability Comparison
SRPT - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Sarepta Therapeutics, Inc. reported a gross profit of 0.00 and revenue of 730.80M. Therefore, the gross margin over that period was 0.0%.
UTHR - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, United Therapeutics Corporation reported a gross profit of 648.10M and revenue of 781.50M. Therefore, the gross margin over that period was 82.9%.
SRPT - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Sarepta Therapeutics, Inc. reported an operating income of 358.43M and revenue of 730.80M, resulting in an operating margin of 49.1%.
UTHR - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, United Therapeutics Corporation reported an operating income of 325.80M and revenue of 781.50M, resulting in an operating margin of 41.7%.
SRPT - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Sarepta Therapeutics, Inc. reported a net income of 330.96M and revenue of 730.80M, resulting in a net margin of 45.3%.
UTHR - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, United Therapeutics Corporation reported a net income of 274.90M and revenue of 781.50M, resulting in a net margin of 35.2%.
Frequently Asked Questions
SRPT and UTHR have a correlation of 0.16, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
SRPT has higher volatility (17.02%) compared to UTHR (8.33%). In terms of maximum drawdown, SRPT dropped -98.17% vs UTHR's -93.18%.
UTHR currently has the higher Sharpe Ratio (1.40 vs -0.56), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
Find the right allocation for SRPT and UTHR
Add both to a portfolio and optimize allocations for your target — whether that's maximizing returns, minimizing drawdowns, or balancing risk across holdings.
Open Portfolio Optimizer