SRPT vs. COST

Last updated Jun 3, 2026

SRPT (Sarepta Therapeutics, Inc.) and COST (Costco Wholesale Corporation) are both stocks. SRPT operates in Biotechnology (Healthcare), while COST operates in Discount Stores (Consumer Defensive). Over the past 10 years, SRPT returned 0.43%/yr vs 22.25%/yr for COST. At a 0.16 correlation, their price movements are largely independent.

Performance

SRPT vs. COST - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Sarepta Therapeutics, Inc. (SRPT) and Costco Wholesale Corporation (COST). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, SRPT achieves a -24.49% return, which is significantly lower than COST's 10.97% return. Over the past 10 years, SRPT has underperformed COST with an annualized return of 0.43%, while COST has yielded a comparatively higher 22.25% annualized return.

SRPT

• 1D: -7.72%
• 1M: -24.38%
• YTD: -24.49%
• 6M: -20.62%
• 1Y: -56.94%
• 3Y*: -49.36%
• 5Y*: -26.11%
• 10Y*: 0.43%

COST

• 1D: 0.86%
• 1M: -5.68%
• YTD: 10.97%
• 6M: 3.79%
• 1Y: -9.20%
• 3Y*: 24.67%
• 5Y*: 21.28%
• 10Y*: 22.25%

*Multi-year figures are annualized to reflect compound growth (CAGR)

SRPT vs. COST - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
SRPT Sarepta Therapeutics, Inc.	-24.49%	-82.30%	26.09%	-25.58%	43.90%	-47.18%	32.12%	18.24%	96.14%	102.84%
COST Costco Wholesale Corporation	10.97%	-5.39%	39.62%	49.00%	-19.05%	51.82%	32.67%	45.70%	10.60%	22.37%

Correlation

The correlation between SRPT and COST is -0.08, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	-0.08
Correlation (3Y) Calculated over the trailing 3-year period	0.08
Correlation (5Y) Calculated over the trailing 5-year period	0.14
Correlation (10Y) Calculated over the trailing 10-year period	0.15
Correlation (All Time) Calculated using the full available price history since Jun 5, 1997	0.16

The correlation between SRPT and COST shifts across timeframes, from -0.08 (1 year) to 0.16 (all time), reflecting how their relationship changes across market environments.

Fundamentals

EPS SRPT : $0.60 COST : $26.51
PE Ratio SRPT : 27.07 COST : 36.00
PS Ratio SRPT : 0.81 COST : 1.08
Total Revenue (TTM) SRPT : $2.18B COST : $293.59B
Gross Profit (TTM) SRPT : $751.34M COST : $11.12B
EBITDA (TTM) SRPT : $107.91M COST : $12.48B

Return for Risk

SRPT vs. COST — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

SRPT

SRPT Risk / Return Rank: 18
SRPT Sharpe Ratio Rank: 17
SRPT Sortino Ratio Rank: 22
SRPT Omega Ratio Rank: 21
SRPT Calmar Ratio Rank: 11
SRPT Martin Ratio Rank: 18

COST

COST Risk / Return Rank: 22
COST Sharpe Ratio Rank: 19
COST Sortino Ratio Rank: 18
COST Omega Ratio Rank: 19
COST Calmar Ratio Rank: 27
COST Martin Ratio Rank: 25

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

SRPT vs. COST - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Sarepta Therapeutics, Inc. (SRPT) and Costco Wholesale Corporation (COST). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	SRPT	COST	Difference
Sharpe ratio Return per unit of total volatility	-0.55	-0.48	-0.07
Sortino ratio Return per unit of downside risk	-0.32	-0.56	+0.25
Omega ratio Gain probability vs. loss probability	0.95	0.93	+0.02
Calmar ratio Return relative to maximum drawdown	-0.79	-0.40	-0.39
Martin ratio Return relative to average drawdown	-1.05	-0.78	-0.27
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

SRPT vs. COST - Sharpe Ratio Comparison

The current SRPT Sharpe Ratio is -0.55, which is comparable to the COST Sharpe Ratio of -0.48. The chart below compares the historical Sharpe Ratios of SRPT and COST, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	SRPT	COST	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.55	-0.48	-0.07
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.38	0.94	-1.32
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.01	1.02	-1.01
Sharpe Ratio (All Time) Calculated using the full available price history	-0.03	0.58	-0.62

Drawdowns

SRPT vs. COST - Drawdown Comparison

The maximum SRPT drawdown since its inception was -98.17%, which is greater than COST's maximum drawdown of -53.39%. Use the drawdown chart below to compare losses from any high point for SRPT and COST.

Drawdown Indicators

	SRPT	COST	Difference
Max Drawdown Largest peak-to-trough decline	-98.17%	-53.39%	-44.78%
Max Drawdown (1Y) Largest decline over 1 year	-72.26%	-19.25%	-53.01%
Max Drawdown (3Y) Largest decline over 3 years	-92.72%	-20.74%	-71.98%
Max Drawdown (5Y) Largest decline over 5 years	-92.72%	-31.40%	-61.32%
Max Drawdown (10Y) Largest decline over 10 years	-93.33%	-31.40%	-61.93%
Current Drawdown Current decline from peak	-90.91%	-12.80%	-78.11%
Average Drawdown Average peak-to-trough decline	-68.14%	-13.36%	-54.78%
Ulcer Index Depth and duration of drawdowns from previous peaks	53.85%	9.92%	+43.93%

Volatility

SRPT vs. COST - Volatility Comparison

Sarepta Therapeutics, Inc. (SRPT) has a higher volatility of 17.44% compared to Costco Wholesale Corporation (COST) at 7.99%. This indicates that SRPT's price experiences larger fluctuations and is considered to be riskier than COST based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	SRPT	COST	Difference
Volatility (1M) Calculated over the trailing 1-month period	17.44%	7.99%	+9.45%
Volatility (6M) Calculated over the trailing 6-month period	53.16%	14.81%	+38.35%
Volatility (1Y) Calculated over the trailing 1-year period	103.50%	19.17%	+84.33%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	69.82%	22.73%	+47.09%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	70.76%	21.95%	+48.81%

Dividends

SRPT vs. COST - Dividend Comparison

SRPT has not paid dividends to shareholders, while COST's dividend yield for the trailing twelve months is around 0.56%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
COST Costco Wholesale Corporation	0.56%	0.59%	0.49%	2.87%	0.76%	0.54%	3.38%	0.86%	1.08%	4.81%	1.09%	4.06%
SRPT Sarepta Therapeutics, Inc.	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Financials

SRPT vs. COST - Profitability Comparison

The chart below illustrates the profitability comparison between Sarepta Therapeutics, Inc. and Costco Wholesale Corporation over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

SRPT - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Sarepta Therapeutics, Inc. reported a gross profit of 0.00 and revenue of 730.80M. Therefore, the gross margin over that period was 0.0%.

COST - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Costco Wholesale Corporation reported a gross profit of -17.68B and revenue of 70.53B. Therefore, the gross margin over that period was -25.1%.

SRPT - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Sarepta Therapeutics, Inc. reported an operating income of 358.43M and revenue of 730.80M, resulting in an operating margin of 49.1%.

COST - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Costco Wholesale Corporation reported an operating income of 2.82B and revenue of 70.53B, resulting in an operating margin of 4.0%.

SRPT - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Sarepta Therapeutics, Inc. reported a net income of 330.96M and revenue of 730.80M, resulting in a net margin of 45.3%.

COST - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Costco Wholesale Corporation reported a net income of 2.19B and revenue of 70.53B, resulting in a net margin of 3.1%.

Frequently Asked Questions

Can I hold both SRPT and COST in my portfolio?

SRPT and COST have a correlation of -0.08, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, SRPT or COST?

SRPT has higher volatility (17.44%) compared to COST (7.99%). In terms of maximum drawdown, SRPT dropped -98.17% vs COST's -53.39%.

Which has better risk-adjusted returns?

COST currently has the higher Sharpe Ratio (-0.48 vs -0.55), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.