SPAQ vs. CANC

Last updated Jun 4, 2026

SPAQ (Horizon Kinetics SPAC Active ETF) and CANC (Tema Oncology ETF) are both Health & Biotech Equities funds. Both are actively managed. Over the past 3 years, SPAQ returned 5.87%/yr vs 107.76%/yr for CANC. At a 0.00 correlation, their price movements are largely independent. SPAQ charges 0.85%/yr vs 0.75%/yr for CANC.

Performance

SPAQ vs. CANC - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Horizon Kinetics SPAC Active ETF (SPAQ) and Tema Oncology ETF (CANC). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, SPAQ achieves a 2.81% return, which is significantly lower than CANC's 4.82% return.

SPAQ

• 1D: 0.00%
• 1M: 1.51%
• YTD: 2.81%
• 6M: 1.64%
• 1Y: 4.98%
• 3Y*: 5.87%
• 5Y*: —
• 10Y*: —

CANC

• 1D: 0.08%
• 1M: -3.73%
• YTD: 4.82%
• 6M: 3.86%
• 1Y: 47.37%
• 3Y*: 107.76%
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

SPAQ vs. CANC - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023
SPAQ Horizon Kinetics SPAC Active ETF	2.81%	7.35%	4.33%	5.52%
CANC Tema Oncology ETF	4.82%	42.92%	-5.37%	462.65%

Correlation

The correlation between SPAQ and CANC is 0.01, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.01
Correlation (3Y) Calculated over the trailing 3-year period	-0.00
Correlation (All Time) Calculated using the full available price history since Jan 31, 2023	0.00

SPAQ vs. CANC - Sectors Allocation Comparison

Sectors	SPAQ	CANC
Financial Services	91.6%	-
Industrials	0.1%	-
Basic Materials	-	-
Communication Services	-	-
Consumer Cyclical	-	-
Consumer Defensive	-	-
Energy	-	-
Healthcare	-	100.0%
Real Estate	-	-
Technology	-	-
Utilities	-	-

Return for Risk

SPAQ vs. CANC — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

SPAQ

SPAQ Risk / Return Rank: 20
SPAQ Sharpe Ratio Rank: 18
SPAQ Sortino Ratio Rank: 17
SPAQ Omega Ratio Rank: 20
SPAQ Calmar Ratio Rank: 21
SPAQ Martin Ratio Rank: 25

CANC

CANC Risk / Return Rank: 69
CANC Sharpe Ratio Rank: 61
CANC Sortino Ratio Rank: 64
CANC Omega Ratio Rank: 54
CANC Calmar Ratio Rank: 90
CANC Martin Ratio Rank: 77

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

SPAQ vs. CANC - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Horizon Kinetics SPAC Active ETF (SPAQ) and Tema Oncology ETF (CANC). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	SPAQ	CANC	Difference
Sharpe ratio: Return per unit of total volatility	0.57	2.06	-1.49
Sortino ratio: Return per unit of downside risk	0.84	2.96	-2.12
Omega ratio: Gain probability vs. loss probability	1.13	1.34	-0.21
Calmar ratio: Return relative to maximum drawdown	0.94	5.49	-4.54
Martin ratio: Return relative to average drawdown	3.39	14.62	-11.23
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

SPAQ vs. CANC - Sharpe Ratio Comparison

The current SPAQ Sharpe Ratio is 0.57, which is lower than the CANC Sharpe Ratio of 2.06. The chart below compares the historical Sharpe Ratios of SPAQ and CANC, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	SPAQ	CANC	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	0.57	2.06	-1.49
Sharpe Ratio (All Time) Calculated using the full available price history	0.86	-0.04	+0.90

Drawdowns

SPAQ vs. CANC - Drawdown Comparison

The maximum SPAQ drawdown since its inception was -5.30%, smaller than the maximum CANC drawdown of -97.53%. Use the drawdown chart below to compare losses from any high point for SPAQ and CANC.

Drawdown Indicators

	SPAQ	CANC	Difference
Max Drawdown Largest peak-to-trough decline	-5.30%	-97.53%	+92.23%
Max Drawdown (1Y) Largest decline over 1 year	-5.30%	-8.67%	+3.37%
Max Drawdown (3Y) Largest decline over 3 years	-5.30%	-30.27%	+24.97%
Current Drawdown Current decline from peak	-0.01%	-56.55%	+56.54%
Average Drawdown Average peak-to-trough decline	-0.54%	-73.19%	+72.65%
Ulcer Index Depth and duration of drawdowns from previous peaks	1.47%	3.25%	-1.78%

Volatility

SPAQ vs. CANC - Volatility Comparison

The current volatility for Horizon Kinetics SPAC Active ETF (SPAQ) is 1.95%, while Tema Oncology ETF (CANC) has a volatility of 6.26%. This indicates that SPAQ experiences smaller price fluctuations and is considered to be less risky than CANC based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	SPAQ	CANC	Difference
Volatility (1M) Calculated over the trailing 1-month period	1.95%	6.26%	-4.31%
Volatility (6M) Calculated over the trailing 6-month period	5.01%	16.69%	-11.68%
Volatility (1Y) Calculated over the trailing 1-year period	8.80%	23.11%	-14.31%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	7.00%	280.27%	-273.27%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	7.00%	280.27%	-273.27%

SPAQ vs. CANC - Expense Ratio Comparison

SPAQ has a 0.85% expense ratio, which is higher than CANC's 0.75% expense ratio.

Dividends

SPAQ vs. CANC - Dividend Comparison

SPAQ's dividend yield for the trailing twelve months is around 16.23%, more than CANC's 0.05% yield.

Position	TTM	2025	2024	2023
CANC Tema Oncology ETF	0.05%	0.06%	3.00%	0.56%
SPAQ Horizon Kinetics SPAC Active ETF	16.23%	16.69%	3.00%	2.60%

Frequently Asked Questions

Can I hold both SPAQ and CANC in my portfolio?

SPAQ and CANC have a correlation of 0.01, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, SPAQ or CANC?

CANC has higher volatility (6.26%) compared to SPAQ (1.95%). In terms of maximum drawdown, SPAQ dropped -5.30% vs CANC's -97.53%.

Which ETF is better, SPAQ or CANC?

On 3-year performance, CANC leads with 107.76% vs 5.87% for SPAQ. On fees, CANC is cheaper at 0.75% per year. On volatility, SPAQ has been the lower-risk option at 1.95%. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF has performed better, SPAQ or CANC?

Over the 3-year period, CANC has performed better with a 107.76% return vs 5.87%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.

Which ETF is cheaper, SPAQ or CANC?

CANC is cheaper with a 0.75% expense ratio, compared with 0.85% for SPAQ.

Which ETF pays a higher dividend yield, SPAQ or CANC?

SPAQ has the higher dividend yield at 16.23%, compared with 0.05% for CANC.

What is the main difference between SPAQ and CANC?

They also come from different issuers: Horizon and Tema. Their fees differ too: 0.85% for SPAQ and 0.75% for CANC.

Which has better risk-adjusted returns?

CANC currently has the higher Sharpe Ratio (2.06 vs 0.57), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.