SDGR vs. SPY
SDGR (Schrodinger, Inc.) is a stock, while SPY (State Street SPDR S&P 500 ETF) is S&P 500 fund tracking the S&P 500 Index. Over the past 5 years, SDGR returned -27.71%/yr vs 12.96%/yr for SPY. At a 0.43 correlation, their price movements are largely independent.
Performance
SDGR vs. SPY - Performance Comparison
Loading charts...
Returns By Period
In the year-to-date period, SDGR achieves a -14.26% return, which is significantly lower than SPY's 8.10% return.
SDGR
- 1D
- 1.93%
- 1M
- 15.26%
- YTD
- -14.26%
- 6M
- -16.59%
- 1Y
- -25.58%
- 3Y*
- -28.74%
- 5Y*
- -27.71%
- 10Y*
- —
SPY
- 1D
- -0.05%
- 1M
- -1.41%
- YTD
- 8.10%
- 6M
- 6.77%
- 1Y
- 22.18%
- 3Y*
- 20.66%
- 5Y*
- 12.96%
- 10Y*
- 15.53%
SDGR vs. SPY - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | |
|---|---|---|---|---|---|---|---|
SDGR Schrodinger, Inc. | -14.26% | -7.31% | -46.12% | 91.55% | -46.34% | -56.01% | 204.54% |
SPY State Street SPDR S&P 500 ETF | 8.10% | 17.72% | 24.89% | 26.18% | -18.18% | 28.73% | 14.42% |
Correlation
The correlation between SDGR and SPY is 0.44, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.44 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.45 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.48 |
Correlation (All Time) Calculated using the full available price history since Feb 6, 2020 | 0.43 |
Compare stocks, funds, or ETFs
Search for stocks, ETFs, and funds for a quick comparison or use the comparison tool for more options.
Return for Risk
SDGR vs. SPY — Risk / Return Rank
SDGR
SPY
SDGR vs. SPY - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Schrodinger, Inc. (SDGR) and State Street SPDR S&P 500 ETF (SPY). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| SDGR | SPY | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -2.29 | ||
| Sortino ratioReturn per unit of downside risk | -2.90 | ||
| Omega ratioGain probability vs. loss probability | 0.95 | 1.33 | -0.38 |
| Calmar ratioReturn relative to maximum drawdown | -0.49 | 2.51 | -3.00 |
| Martin ratioReturn relative to average drawdown | -0.82 | 11.15 | -11.97 |
Loading charts...
Drawdowns
SDGR vs. SPY - Drawdown Comparison
The maximum SDGR drawdown since its inception was -90.21%, which is greater than SPY's maximum drawdown of -55.19%. Use the drawdown chart below to compare losses from any high point for SDGR and SPY.
Loading charts...
Drawdown Indicators
| SDGR | SPY | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -90.21% | -55.19% | -35.02% |
Max Drawdown (1Y)Largest decline over 1 year | -51.93% | -8.88% | -43.05% |
Max Drawdown (3Y)Largest decline over 3 years | -80.01% | -18.76% | -61.25% |
Max Drawdown (5Y)Largest decline over 5 years | -85.95% | -24.50% | -61.45% |
Max Drawdown (10Y)Largest decline over 10 years | — | -33.72% | — |
Current DrawdownCurrent decline from peak | -86.44% | -3.22% | -83.22% |
Average DrawdownAverage peak-to-trough decline | -64.18% | -9.03% | -55.15% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 31.37% | 1.99% | +29.38% |
Volatility
SDGR vs. SPY - Volatility Comparison
Schrodinger, Inc. (SDGR) has a higher volatility of 18.42% compared to State Street SPDR S&P 500 ETF (SPY) at 4.85%. This indicates that SDGR's price experiences larger fluctuations and is considered to be riskier than SPY based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
Loading charts...
Volatility by Period
| SDGR | SPY | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 18.42% | 4.85% | +13.57% |
Volatility (6M)Calculated over the trailing 6-month period | 38.72% | 9.81% | +28.91% |
Volatility (1Y)Calculated over the trailing 1-year period | 51.43% | 12.47% | +38.96% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 63.41% | 17.15% | +46.26% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 69.85% | 17.95% | +51.90% |
Dividends
SDGR vs. SPY - Dividend Comparison
SDGR has not paid dividends to shareholders, while SPY's dividend yield for the trailing twelve months is around 1.03%.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
SDGR Schrodinger, Inc. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
SPY State Street SPDR S&P 500 ETF | 1.03% | 1.07% | 1.21% | 1.40% | 1.65% | 1.20% | 1.52% | 1.75% | 2.04% | 1.80% | 2.03% | 2.06% |
Frequently Asked Questions
SDGR and SPY have a correlation of 0.44, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
SDGR has higher volatility (18.42%) compared to SPY (4.85%). In terms of maximum drawdown, SDGR dropped -90.21% vs SPY's -55.19%.
SPY currently has the higher Sharpe Ratio (1.79 vs -0.50), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
Find the right allocation for SDGR and SPY
Add both to a portfolio and optimize allocations for your target — whether that's maximizing returns, minimizing drawdowns, or balancing risk across holdings.
Open Portfolio Optimizer