SCLX vs. JNJ

Last updated Jun 23, 2026

SCLX (Scilex Holding Company) and JNJ (Johnson & Johnson) are both stocks. Both operate in the Drug Manufacturers - General industry within the Healthcare sector. Over the past 5 years, SCLX returned -49.84%/yr vs 10.36%/yr for JNJ. At a 0.02 correlation, their price movements are largely independent.

Performance

SCLX vs. JNJ - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Scilex Holding Company (SCLX) and Johnson & Johnson (JNJ). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, SCLX achieves a -9.56% return, which is significantly lower than JNJ's 13.00% return.

SCLX

• 1D: -8.03%
• 1M: 80.58%
• YTD: -9.56%
• 6M: -22.68%
• 1Y: 124.71%
• 3Y*: -63.15%
• 5Y*: -49.84%
• 10Y*: —

JNJ

• 1D: 1.27%
• 1M: -0.73%
• YTD: 13.00%
• 6M: 12.80%
• 1Y: 58.27%
• 3Y*: 15.12%
• 5Y*: 10.36%
• 10Y*: 10.15%

*Multi-year figures are annualized to reflect compound growth (CAGR)

SCLX vs. JNJ - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021
SCLX Scilex Holding Company	-9.56%	-18.25%	-79.10%	-48.87%	-60.26%	1.93%
JNJ Johnson & Johnson	13.00%	47.48%	-4.81%	-8.58%	5.97%	13.87%

Correlation

The correlation between SCLX and JNJ is -0.03, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	-0.03
Correlation (3Y) Calculated over the trailing 3-year period	0.03
Correlation (5Y) Calculated over the trailing 5-year period	0.02
Correlation (All Time) Calculated using the full available price history since Mar 5, 2021	0.02

Fundamentals

Market Cap SCLX : $75.80M JNJ : $565.55B
EPS SCLX : -$35.27 JNJ : $8.65
PS Ratio SCLX : 2.59 JNJ : 5.84
Total Revenue (TTM) SCLX : $30.25M JNJ : $96.36B
Gross Profit (TTM) SCLX : $18.07M JNJ : $66.60B
EBITDA (TTM) SCLX : -$352.83M JNJ : $31.62B

Return for Risk

SCLX vs. JNJ — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

SCLX

SCLX Risk / Return Rank: 72
SCLX Sharpe Ratio Rank: 72
SCLX Sortino Ratio Rank: 79
SCLX Omega Ratio Rank: 75
SCLX Calmar Ratio Rank: 71
SCLX Martin Ratio Rank: 64

JNJ

JNJ Risk / Return Rank: 95
JNJ Sharpe Ratio Rank: 97
JNJ Sortino Ratio Rank: 98
JNJ Omega Ratio Rank: 96
JNJ Calmar Ratio Rank: 93
JNJ Martin Ratio Rank: 94

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

SCLX vs. JNJ - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Scilex Holding Company (SCLX) and Johnson & Johnson (JNJ). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	SCLX	JNJ	Difference
Sharpe ratio: Return per unit of total volatility	1.00	3.42	-2.42
Sortino ratio: Return per unit of downside risk	2.17	4.86	-2.69
Omega ratio: Gain probability vs. loss probability	1.25	1.61	-0.36
Calmar ratio: Return relative to maximum drawdown	1.56	5.34	-3.78
Martin ratio: Return relative to average drawdown	2.31	15.57	-13.27

SCLX vs. JNJ - Sharpe Ratio Comparison

The current SCLX Sharpe Ratio is 1.00, which is lower than the JNJ Sharpe Ratio of 3.42. The chart below compares the historical Sharpe Ratios of SCLX and JNJ, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

SCLX vs. JNJ - Drawdown Comparison

The maximum SCLX drawdown since its inception was -99.23%, which is greater than JNJ's maximum drawdown of -50.67%. Use the drawdown chart below to compare losses from any high point for SCLX and JNJ.

Drawdown Indicators

	SCLX	JNJ	Difference
Max Drawdown Largest peak-to-trough decline	-99.23%	-50.67%	-48.56%
Max Drawdown (1Y) Largest decline over 1 year	-80.27%	-10.96%	-69.31%
Max Drawdown (3Y) Largest decline over 3 years	-98.20%	-15.95%	-82.25%
Max Drawdown (5Y) Largest decline over 5 years	-99.23%	-18.41%	-80.82%
Max Drawdown (10Y) Largest decline over 10 years	—	-27.37%	—
Current Drawdown Current decline from peak	-97.87%	-6.41%	-91.46%
Average Drawdown Average peak-to-trough decline	-57.08%	-11.90%	-45.18%
Ulcer Index Depth and duration of drawdowns from previous peaks	54.23%	3.75%	+50.48%

Volatility

SCLX vs. JNJ - Volatility Comparison

Scilex Holding Company (SCLX) has a higher volatility of 44.68% compared to Johnson & Johnson (JNJ) at 6.32%. This indicates that SCLX's price experiences larger fluctuations and is considered to be riskier than JNJ based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	SCLX	JNJ	Difference
Volatility (1M) Calculated over the trailing 1-month period	44.68%	6.32%	+38.36%
Volatility (6M) Calculated over the trailing 6-month period	75.51%	12.32%	+63.19%
Volatility (1Y) Calculated over the trailing 1-year period	125.36%	17.14%	+108.22%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	112.53%	16.92%	+95.61%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	109.27%	18.51%	+90.76%

Dividends

SCLX vs. JNJ - Dividend Comparison

SCLX has not paid dividends to shareholders, while JNJ's dividend yield for the trailing twelve months is around 2.27%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
JNJ Johnson & Johnson	2.27%	2.48%	3.40%	3.00%	2.52%	2.45%	2.53%	2.57%	2.74%	2.38%	2.73%	2.87%
SCLX Scilex Holding Company	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Financials

Frequently Asked Questions

Can I hold both SCLX and JNJ in my portfolio?

SCLX and JNJ have a correlation of -0.03, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, SCLX or JNJ?

SCLX has higher volatility (44.68%) compared to JNJ (6.32%). In terms of maximum drawdown, SCLX dropped -99.23% vs JNJ's -50.67%.

Which has better risk-adjusted returns?

JNJ currently has the higher Sharpe Ratio (3.42 vs 1.00), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.