SC0T.DE vs. LYPE.DE

Last updated Jun 5, 2026

SC0T.DE (Invesco European Health Care Sector UCITS ETF) and LYPE.DE (Amundi MSCI World Health Care UCITS ETF EUR Acc) are both Health & Biotech Equities funds - SC0T.DE tracks the STOXX® Europe 600 Optimised Health Care while LYPE.DE tracks the MSCI World Health Care. Both are passively managed. Over the past 10 years, SC0T.DE returned 5.80%/yr vs 7.45%/yr for LYPE.DE. A 0.76 correlation means they provide meaningful diversification when combined. SC0T.DE charges 0.20%/yr vs 0.30%/yr for LYPE.DE.

Performance

SC0T.DE vs. LYPE.DE - Performance Comparison

The chart below illustrates the hypothetical performance of a €10,000 investment in Invesco European Health Care Sector UCITS ETF (SC0T.DE) and Amundi MSCI World Health Care UCITS ETF EUR Acc (LYPE.DE). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, SC0T.DE achieves a -3.57% return, which is significantly lower than LYPE.DE's -2.00% return. Over the past 10 years, SC0T.DE has underperformed LYPE.DE with an annualized return of 5.80%, while LYPE.DE has yielded a comparatively higher 7.45% annualized return.

SC0T.DE

• 1D: 2.93%
• 1M: 0.25%
• YTD: -3.57%
• 6M: -2.50%
• 1Y: 2.66%
• 3Y*: 2.80%
• 5Y*: 4.81%
• 10Y*: 5.80%

LYPE.DE

• 1D: 2.79%
• 1M: 3.48%
• YTD: -2.00%
• 6M: -1.61%
• 1Y: 9.70%
• 3Y*: 2.46%
• 5Y*: 5.27%
• 10Y*: 7.45%

*Multi-year figures are annualized to reflect compound growth (CAGR)

SC0T.DE vs. LYPE.DE - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
SC0T.DE Invesco European Health Care Sector UCITS ETF	-3.57%	8.45%	6.96%	5.35%	-7.56%	25.20%	-1.18%	32.22%	-1.43%	4.65%
LYPE.DE Amundi MSCI World Health Care UCITS ETF EUR Acc	-2.00%	2.17%	7.03%	-0.27%	-0.17%	30.38%	2.44%	27.39%	5.67%	5.56%

Correlation

The correlation between SC0T.DE and LYPE.DE is 0.74, which is moderate. They share some common price drivers but move independently often enough to provide real diversification benefit when combined.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.74
Correlation (3Y) Calculated over the trailing 3-year period	0.72
Correlation (5Y) Calculated over the trailing 5-year period	0.74
Correlation (10Y) Calculated over the trailing 10-year period	0.77
Correlation (All Time) Calculated using the full available price history since Sep 30, 2010	0.76

The correlation between SC0T.DE and LYPE.DE has been stable across timeframes, ranging from 0.72 to 0.77 - a consistent structural relationship.

Return for Risk

SC0T.DE vs. LYPE.DE — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

SC0T.DE

SC0T.DE Risk / Return Rank: 12
SC0T.DE Sharpe Ratio Rank: 12
SC0T.DE Sortino Ratio Rank: 12
SC0T.DE Omega Ratio Rank: 12
SC0T.DE Calmar Ratio Rank: 12
SC0T.DE Martin Ratio Rank: 12

LYPE.DE

LYPE.DE Risk / Return Rank: 21
LYPE.DE Sharpe Ratio Rank: 21
LYPE.DE Sortino Ratio Rank: 22
LYPE.DE Omega Ratio Rank: 20
LYPE.DE Calmar Ratio Rank: 21
LYPE.DE Martin Ratio Rank: 20

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

SC0T.DE vs. LYPE.DE - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Invesco European Health Care Sector UCITS ETF (SC0T.DE) and Amundi MSCI World Health Care UCITS ETF EUR Acc (LYPE.DE). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	SC0T.DE	LYPE.DE	Difference
Sharpe ratio: Return per unit of total volatility	0.20	0.68	-0.49
Sortino ratio: Return per unit of downside risk	0.40	1.13	-0.72
Omega ratio: Gain probability vs. loss probability	1.05	1.13	-0.08
Calmar ratio: Return relative to maximum drawdown	0.24	0.93	-0.68
Martin ratio: Return relative to average drawdown	0.56	2.27	-1.70
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

SC0T.DE vs. LYPE.DE - Sharpe Ratio Comparison

The current SC0T.DE Sharpe Ratio is 0.20, which is lower than the LYPE.DE Sharpe Ratio of 0.68. The chart below compares the historical Sharpe Ratios of SC0T.DE and LYPE.DE, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	SC0T.DE	LYPE.DE	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	0.20	0.68	-0.49
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.32	0.39	-0.07
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.37	0.51	-0.13
Sharpe Ratio (All Time) Calculated using the full available price history	0.63	0.76	-0.13

Drawdowns

SC0T.DE vs. LYPE.DE - Drawdown Comparison

The maximum SC0T.DE drawdown since its inception was -26.52%, roughly equal to the maximum LYPE.DE drawdown of -25.95%. Use the drawdown chart below to compare losses from any high point for SC0T.DE and LYPE.DE.

Drawdown Indicators

	SC0T.DE	LYPE.DE	Difference
Max Drawdown Largest peak-to-trough decline	-26.52%	-25.95%	-0.57%
Max Drawdown (1Y) Largest decline over 1 year	-12.87%	-10.21%	-2.66%
Max Drawdown (3Y) Largest decline over 3 years	-21.67%	-21.30%	-0.37%
Max Drawdown (5Y) Largest decline over 5 years	-21.67%	-21.30%	-0.37%
Max Drawdown (10Y) Largest decline over 10 years	-26.52%	-25.95%	-0.57%
Current Drawdown Current decline from peak	-9.59%	-8.75%	-0.84%
Average Drawdown Average peak-to-trough decline	-6.03%	-5.06%	-0.97%
Ulcer Index Depth and duration of drawdowns from previous peaks	5.58%	4.18%	+1.40%

Volatility

SC0T.DE vs. LYPE.DE - Volatility Comparison

Invesco European Health Care Sector UCITS ETF (SC0T.DE) has a higher volatility of 5.31% compared to Amundi MSCI World Health Care UCITS ETF EUR Acc (LYPE.DE) at 4.96%. This indicates that SC0T.DE's price experiences larger fluctuations and is considered to be riskier than LYPE.DE based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	SC0T.DE	LYPE.DE	Difference
Volatility (1M) Calculated over the trailing 1-month period	5.31%	4.96%	+0.35%
Volatility (6M) Calculated over the trailing 6-month period	11.43%	9.76%	+1.67%
Volatility (1Y) Calculated over the trailing 1-year period	15.98%	13.82%	+2.16%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	14.84%	13.41%	+1.43%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	15.39%	14.64%	+0.75%

SC0T.DE vs. LYPE.DE - Expense Ratio Comparison

SC0T.DE has a 0.20% expense ratio, which is lower than LYPE.DE's 0.30% expense ratio.

Dividends

SC0T.DE vs. LYPE.DE - Dividend Comparison

Neither SC0T.DE nor LYPE.DE has paid dividends to shareholders.

Tickers have no history of dividend payments

Frequently Asked Questions

Can I hold both SC0T.DE and LYPE.DE in my portfolio?

SC0T.DE and LYPE.DE have a correlation of 0.74, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which ETF is better, SC0T.DE or LYPE.DE?

On fees, SC0T.DE is cheaper at 0.20% per year. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF is cheaper, SC0T.DE or LYPE.DE?

SC0T.DE is cheaper with a 0.20% expense ratio, compared with 0.30% for LYPE.DE.

What is the main difference between SC0T.DE and LYPE.DE?

SC0T.DE tracks STOXX® Europe 600 Optimised Health Care, while LYPE.DE tracks MSCI World Health Care. They also come from different issuers: Invesco and Amundi. Their fees differ too: 0.20% for SC0T.DE and 0.30% for LYPE.DE.