RVMD vs. EXEL

Last updated Apr 1, 2026

Compare and contrast key facts about Revolution Medicines, Inc. (RVMD) and Exelixis, Inc. (EXEL).

Performance

RVMD vs. EXEL - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Revolution Medicines, Inc. (RVMD) and Exelixis, Inc. (EXEL). The values are adjusted to include any dividend payments, if applicable.

RVMD vs. EXEL - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020
RVMD Revolution Medicines, Inc.	22.10%	82.10%	52.51%	20.40%	-5.36%	-36.42%	36.99%
EXEL Exelixis, Inc.	-2.14%	31.62%	38.81%	49.56%	-12.25%	-8.92%	-0.89%

Fundamentals

EPS RVMD : -$5.09 EXEL : $2.76
Total Revenue (TTM) RVMD : $0.00 EXEL : $2.32B
Gross Profit (TTM) RVMD : $0.00 EXEL : $2.24B
EBITDA (TTM) RVMD : -$1.00B EXEL : $934.65M

Returns By Period

In the year-to-date period, RVMD achieves a 22.10% return, which is significantly higher than EXEL's -2.14% return.

RVMD

• 1D: 4.90%
• 1M: -4.68%
• YTD: 22.10%
• 6M: 108.24%
• 1Y: 175.03%
• 3Y*: 64.97%
• 5Y*: 15.73%
• 10Y*: —

EXEL

• 1D: 2.24%
• 1M: -2.66%
• YTD: -2.14%
• 6M: 3.85%
• 1Y: 16.17%
• 3Y*: 30.25%
• 5Y*: 13.15%
• 10Y*: 26.62%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

RVMD vs. EXEL — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

RVMD

RVMD Risk / Return Rank: 96
RVMD Sharpe Ratio Rank: 97
RVMD Sortino Ratio Rank: 97
RVMD Omega Ratio Rank: 96
RVMD Calmar Ratio Rank: 96
RVMD Martin Ratio Rank: 94

EXEL

EXEL Risk / Return Rank: 56
EXEL Sharpe Ratio Rank: 56
EXEL Sortino Ratio Rank: 52
EXEL Omega Ratio Rank: 54
EXEL Calmar Ratio Rank: 58
EXEL Martin Ratio Rank: 58

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

RVMD vs. EXEL - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Revolution Medicines, Inc. (RVMD) and Exelixis, Inc. (EXEL). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	RVMD	EXEL	Difference
Sharpe ratio Return per unit of total volatility	3.21	0.37	+2.84
Sortino ratio Return per unit of downside risk	4.05	0.83	+3.22
Omega ratio Gain probability vs. loss probability	1.57	1.12	+0.45
Calmar ratio Return relative to maximum drawdown	6.43	0.67	+5.76
Martin ratio Return relative to average drawdown	15.24	1.55	+13.68
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

RVMD vs. EXEL - Sharpe Ratio Comparison

The current RVMD Sharpe Ratio is 3.21, which is higher than the EXEL Sharpe Ratio of 0.37. The chart below compares the historical Sharpe Ratios of RVMD and EXEL, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	RVMD	EXEL	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	3.21	0.37	+2.84
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.26	0.36	-0.10
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	0.60	—
Sharpe Ratio (All Time) Calculated using the full available price history	0.34	0.07	+0.28

Correlation

The correlation between RVMD and EXEL is 0.33, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

RVMD vs. EXEL - Dividend Comparison

Neither RVMD nor EXEL has paid dividends to shareholders.

Tickers have no history of dividend payments

Drawdowns

RVMD vs. EXEL - Drawdown Comparison

The maximum RVMD drawdown since its inception was -73.29%, smaller than the maximum EXEL drawdown of -97.38%. Use the drawdown chart below to compare losses from any high point for RVMD and EXEL.

Drawdown Indicators

	RVMD	EXEL	Difference
Max Drawdown Largest peak-to-trough decline	-73.29%	-97.38%	+24.09%
Max Drawdown (1Y) Largest decline over 1 year	-24.95%	-25.34%	+0.39%
Max Drawdown (5Y) Largest decline over 5 years	-69.35%	-41.47%	-27.88%
Max Drawdown (10Y) Largest decline over 10 years	—	-57.20%	—
Current Drawdown Current decline from peak	-21.11%	-12.91%	-8.20%
Average Drawdown Average peak-to-trough decline	-36.66%	-71.55%	+34.89%
Ulcer Index Depth and duration of drawdowns from previous peaks	10.52%	10.85%	-0.33%

Volatility

RVMD vs. EXEL - Volatility Comparison

Revolution Medicines, Inc. (RVMD) has a higher volatility of 9.83% compared to Exelixis, Inc. (EXEL) at 6.86%. This indicates that RVMD's price experiences larger fluctuations and is considered to be riskier than EXEL based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	RVMD	EXEL	Difference
Volatility (1M) Calculated over the trailing 1-month period	9.83%	6.86%	+2.97%
Volatility (6M) Calculated over the trailing 6-month period	39.79%	26.58%	+13.21%
Volatility (1Y) Calculated over the trailing 1-year period	55.11%	43.76%	+11.35%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	60.46%	36.84%	+23.62%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	64.05%	44.88%	+19.17%

Financials