RMQAX vs. RYOIX

Last updated Jun 24, 2026

RMQAX (Rydex Monthly Rebalance NASDAQ-100 2x Strategy Fund) and RYOIX (Rydex Biotechnology Fund) are both mutual funds - RMQAX is a Leveraged Equities fund managed by Rydex Funds, while RYOIX is a Health & Biotech Equities fund managed by Rydex Funds. Over the past 10 years, RMQAX returned 38.76%/yr vs 10.54%/yr for RYOIX. A 0.62 correlation means they provide meaningful diversification when combined. RMQAX charges 1.32%/yr vs 1.36%/yr for RYOIX.

Performance

RMQAX vs. RYOIX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Rydex Monthly Rebalance NASDAQ-100 2x Strategy Fund (RMQAX) and Rydex Biotechnology Fund (RYOIX). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, RMQAX achieves a 37.04% return, which is significantly higher than RYOIX's 11.45% return. Over the past 10 years, RMQAX has outperformed RYOIX with an annualized return of 38.76%, while RYOIX has yielded a comparatively lower 10.54% annualized return.

RMQAX

• 1D: -0.39%
• 1M: 5.17%
• YTD: 37.04%
• 6M: 33.32%
• 1Y: 76.67%
• 3Y*: 47.95%
• 5Y*: 24.14%
• 10Y*: 38.76%

RYOIX

• 1D: 2.06%
• 1M: 5.30%
• YTD: 11.45%
• 6M: 9.38%
• 1Y: 49.16%
• 3Y*: 15.68%
• 5Y*: 5.29%
• 10Y*: 10.54%

*Multi-year figures are annualized to reflect compound growth (CAGR)

RMQAX vs. RYOIX - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
RMQAX Rydex Monthly Rebalance NASDAQ-100 2x Strategy Fund	37.04%	33.92%	44.76%	115.91%	-59.93%	56.36%	101.06%	80.80%	-7.28%	69.80%
RYOIX Rydex Biotechnology Fund	11.45%	30.62%	-0.95%	6.06%	-13.04%	2.05%	21.94%	30.69%	-8.94%	29.68%

Correlation

The correlation between RMQAX and RYOIX is 0.35, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.35
Correlation (3Y) Calculated over the trailing 3-year period	0.43
Correlation (5Y) Calculated over the trailing 5-year period	0.55
Correlation (10Y) Calculated over the trailing 10-year period	0.61
Correlation (All Time) Calculated using the full available price history since Jan 2, 2015	0.62

Over the past year, the correlation between RMQAX and RYOIX has dropped to 0.35 - well below their long-term average of 0.62, suggesting their price drivers have been diverging.

Return for Risk

RMQAX vs. RYOIX — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

RMQAX

RMQAX Risk / Return Rank: 62
RMQAX Sharpe Ratio Rank: 72
RMQAX Sortino Ratio Rank: 50
RMQAX Omega Ratio Rank: 52
RMQAX Calmar Ratio Rank: 75
RMQAX Martin Ratio Rank: 61

RYOIX

RYOIX Risk / Return Rank: 84
RYOIX Sharpe Ratio Rank: 82
RYOIX Sortino Ratio Rank: 80
RYOIX Omega Ratio Rank: 64
RYOIX Calmar Ratio Rank: 96
RYOIX Martin Ratio Rank: 96

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

RMQAX vs. RYOIX - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Rydex Monthly Rebalance NASDAQ-100 2x Strategy Fund (RMQAX) and Rydex Biotechnology Fund (RYOIX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	RMQAX	RYOIX	Difference
Sharpe ratio: Return per unit of total volatility	2.27	2.47	-0.20
Sortino ratio: Return per unit of downside risk	2.72	3.49	-0.77
Omega ratio: Gain probability vs. loss probability	1.36	1.41	-0.04
Calmar ratio: Return relative to maximum drawdown	3.24	5.80	-2.57
Martin ratio: Return relative to average drawdown	11.40	21.13	-9.73

RMQAX vs. RYOIX - Sharpe Ratio Comparison

The current RMQAX Sharpe Ratio is 2.27, which is comparable to the RYOIX Sharpe Ratio of 2.47. The chart below compares the historical Sharpe Ratios of RMQAX and RYOIX, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

RMQAX vs. RYOIX - Drawdown Comparison

The maximum RMQAX drawdown since its inception was -63.18%, smaller than the maximum RYOIX drawdown of -74.43%. Use the drawdown chart below to compare losses from any high point for RMQAX and RYOIX.

Drawdown Indicators

	RMQAX	RYOIX	Difference
Max Drawdown Largest peak-to-trough decline	-63.18%	-74.43%	+11.25%
Max Drawdown (1Y) Largest decline over 1 year	-24.96%	-8.43%	-16.53%
Max Drawdown (3Y) Largest decline over 3 years	-42.45%	-23.47%	-18.98%
Max Drawdown (5Y) Largest decline over 5 years	-63.18%	-33.66%	-29.52%
Max Drawdown (10Y) Largest decline over 10 years	-63.18%	-33.66%	-29.52%
Current Drawdown Current decline from peak	-2.21%	0.00%	-2.21%
Average Drawdown Average peak-to-trough decline	-12.87%	-27.59%	+14.72%
Ulcer Index Depth and duration of drawdowns from previous peaks	7.07%	2.31%	+4.76%

Volatility

RMQAX vs. RYOIX - Volatility Comparison

Rydex Monthly Rebalance NASDAQ-100 2x Strategy Fund (RMQAX) has a higher volatility of 17.06% compared to Rydex Biotechnology Fund (RYOIX) at 6.63%. This indicates that RMQAX's price experiences larger fluctuations and is considered to be riskier than RYOIX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	RMQAX	RYOIX	Difference
Volatility (1M) Calculated over the trailing 1-month period	17.06%	6.63%	+10.43%
Volatility (6M) Calculated over the trailing 6-month period	28.56%	15.35%	+13.21%
Volatility (1Y) Calculated over the trailing 1-year period	35.62%	19.83%	+15.79%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	46.68%	21.25%	+25.43%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	46.68%	23.23%	+23.45%

RMQAX vs. RYOIX - Expense Ratio Comparison

RMQAX has a 1.32% expense ratio, which is lower than RYOIX's 1.36% expense ratio.

Dividends

RMQAX vs. RYOIX - Dividend Comparison

RMQAX's dividend yield for the trailing twelve months is around 26.47%, more than RYOIX's 11.28% yield.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
RMQAX Rydex Monthly Rebalance NASDAQ-100 2x Strategy Fund	26.47%	36.27%	26.02%	3.76%	0.00%	2.18%	5.30%	0.10%	0.00%	0.00%	0.00%	0.00%
RYOIX Rydex Biotechnology Fund	11.28%	12.57%	14.61%	0.00%	1.29%	19.39%	7.28%	8.58%	14.11%	5.38%	0.00%	1.45%

Frequently Asked Questions

Can I hold both RMQAX and RYOIX in my portfolio?

RMQAX and RYOIX have a correlation of 0.35, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, RMQAX or RYOIX?

RMQAX has higher volatility (17.06%) compared to RYOIX (6.63%). In terms of maximum drawdown, RMQAX dropped -63.18% vs RYOIX's -74.43%.

Which has better risk-adjusted returns?

RYOIX currently has the higher Sharpe Ratio (2.47 vs 2.27), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.