RLMD vs. MIESY

Last updated Jun 5, 2026

RLMD (Relmada Therapeutics, Inc.) and MIESY (Mitsui Engineering & Shipbuilding Co Ltd ADR) are both stocks. RLMD operates in Biotechnology (Healthcare), while MIESY operates in Aerospace & Defense (Industrials). Over the past 5 years, RLMD returned -26.85%/yr vs 43.84%/yr for MIESY. At a correlation of -0.02, they often move in opposite directions.

Performance

RLMD vs. MIESY - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Relmada Therapeutics, Inc. (RLMD) and Mitsui Engineering & Shipbuilding Co Ltd ADR (MIESY). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, RLMD achieves a 30.64% return, which is significantly higher than MIESY's -35.89% return.

RLMD

• 1D: -0.32%
• 1M: -14.15%
• YTD: 30.64%
• 6M: 57.75%
• 1Y: 755.13%
• 3Y*: 30.34%
• 5Y*: -26.85%
• 10Y*: -6.23%

MIESY

• 1D: 0.00%
• 1M: -20.82%
• YTD: -35.89%
• 6M: -35.89%
• 1Y: 160.89%
• 3Y*: 98.87%
• 5Y*: 43.84%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

RLMD vs. MIESY - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020
RLMD Relmada Therapeutics, Inc.	30.64%	828.85%	-87.44%	18.62%	-84.51%	-29.75%	-28.84%
MIESY Mitsui Engineering & Shipbuilding Co Ltd ADR	-35.89%	493.50%	38.78%	82.78%	-36.21%	29.70%	-70.00%

Correlation

The correlation between RLMD and MIESY is 0.01, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.01
Correlation (3Y) Calculated over the trailing 3-year period	-0.02
Correlation (5Y) Calculated over the trailing 5-year period	-0.03
Correlation (All Time) Calculated using the full available price history since May 28, 2020	-0.02

Fundamentals

Market Cap RLMD : $546.43M MIESY : $2.66B
EPS RLMD : -$1.06 MIESY : $386.63
PB Ratio RLMD : 2.50 MIESY : 0.01
Total Revenue (TTM) RLMD : $0.00 MIESY : $358.09B
Gross Profit (TTM) RLMD : $0.00 MIESY : $70.42B
EBITDA (TTM) RLMD : -$60.34M MIESY : $49.65B

Return for Risk

RLMD vs. MIESY — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

RLMD

RLMD Risk / Return Rank: 98
RLMD Sharpe Ratio Rank: 99
RLMD Sortino Ratio Rank: 98
RLMD Omega Ratio Rank: 95
RLMD Calmar Ratio Rank: 99
RLMD Martin Ratio Rank: 99

MIESY

MIESY Risk / Return Rank: 87
MIESY Sharpe Ratio Rank: 64
MIESY Sortino Ratio Rank: 99
MIESY Omega Ratio Rank: 100
MIESY Calmar Ratio Rank: 84
MIESY Martin Ratio Rank: 89

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

RLMD vs. MIESY - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Relmada Therapeutics, Inc. (RLMD) and Mitsui Engineering & Shipbuilding Co Ltd ADR (MIESY). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	RLMD	MIESY	Difference
Sharpe ratio: Return per unit of total volatility	6.20	0.70	+5.50
Sortino ratio: Return per unit of downside risk	5.49	6.64	-1.15
Omega ratio: Gain probability vs. loss probability	1.60	4.00	-2.40
Calmar ratio: Return relative to maximum drawdown	21.31	3.26	+18.05
Martin ratio: Return relative to average drawdown	48.79	11.22	+37.57
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

RLMD vs. MIESY - Sharpe Ratio Comparison

The current RLMD Sharpe Ratio is 6.20, which is higher than the MIESY Sharpe Ratio of 0.70. The chart below compares the historical Sharpe Ratios of RLMD and MIESY, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	RLMD	MIESY	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	6.20	0.70	+5.50
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.23	0.38	-0.61
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	-0.05	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.16	0.14	-0.30

Drawdowns

RLMD vs. MIESY - Drawdown Comparison

The maximum RLMD drawdown since its inception was -99.66%, which is greater than MIESY's maximum drawdown of -78.18%. Use the drawdown chart below to compare losses from any high point for RLMD and MIESY.

Drawdown Indicators

	RLMD	MIESY	Difference
Max Drawdown Largest peak-to-trough decline	-99.66%	-78.18%	-21.48%
Max Drawdown (1Y) Largest decline over 1 year	-35.78%	-50.28%	+14.50%
Max Drawdown (3Y) Largest decline over 3 years	-96.30%	-60.56%	-35.74%
Max Drawdown (5Y) Largest decline over 5 years	-99.32%	-60.56%	-38.76%
Max Drawdown (10Y) Largest decline over 10 years	-99.50%	—	—
Current Drawdown Current decline from peak	-91.52%	-50.28%	-41.24%
Average Drawdown Average peak-to-trough decline	-79.70%	-54.63%	-25.07%
Ulcer Index Depth and duration of drawdowns from previous peaks	15.60%	14.52%	+1.08%

Volatility

RLMD vs. MIESY - Volatility Comparison

The current volatility for Relmada Therapeutics, Inc. (RLMD) is 20.17%, while Mitsui Engineering & Shipbuilding Co Ltd ADR (MIESY) has a volatility of 23.35%. This indicates that RLMD experiences smaller price fluctuations and is considered to be less risky than MIESY based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	RLMD	MIESY	Difference
Volatility (1M) Calculated over the trailing 1-month period	20.17%	23.35%	-3.18%
Volatility (6M) Calculated over the trailing 6-month period	68.88%	38.90%	+29.98%
Volatility (1Y) Calculated over the trailing 1-year period	123.04%	233.18%	-110.14%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	116.20%	120.08%	-3.88%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	114.25%	116.02%	-1.77%

Dividends

RLMD vs. MIESY - Dividend Comparison

Neither RLMD nor MIESY has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both RLMD and MIESY in my portfolio?

RLMD and MIESY have a correlation of 0.01, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, RLMD or MIESY?

MIESY has higher volatility (23.35%) compared to RLMD (20.17%). In terms of maximum drawdown, RLMD dropped -99.66% vs MIESY's -78.18%.

Which has better risk-adjusted returns?

RLMD currently has the higher Sharpe Ratio (6.20 vs 0.70), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.