RGEN vs. STIP

Last updated Jun 4, 2026

RGEN (Repligen Corporation) is a stock, while STIP (iShares 0-5 Year TIPS Bond ETF) is Inflation-Protected Bonds fund tracking the Barclays Capital U.S. Treasury Inflation-Protected Securities (TIPS) 0-5 Years Index (Series-L). Over the past 10 years, RGEN returned 17.24%/yr vs 3.18%/yr for STIP. At a 0.01 correlation, their price movements are largely independent.

Performance

RGEN vs. STIP - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Repligen Corporation (RGEN) and iShares 0-5 Year TIPS Bond ETF (STIP). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, RGEN achieves a -25.71% return, which is significantly lower than STIP's 2.04% return. Over the past 10 years, RGEN has outperformed STIP with an annualized return of 17.24%, while STIP has yielded a comparatively lower 3.18% annualized return.

RGEN

• 1D: 0.50%
• 1M: 2.98%
• YTD: -25.71%
• 6M: -26.90%
• 1Y: -2.15%
• 3Y*: -10.05%
• 5Y*: -7.30%
• 10Y*: 17.24%

STIP

• 1D: 0.00%
• 1M: 0.03%
• YTD: 2.04%
• 6M: 2.03%
• 1Y: 4.68%
• 3Y*: 5.23%
• 5Y*: 3.37%
• 10Y*: 3.18%

*Multi-year figures are annualized to reflect compound growth (CAGR)

RGEN vs. STIP - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
RGEN Repligen Corporation	-25.71%	13.84%	-19.94%	6.20%	-36.07%	38.20%	107.17%	75.39%	45.37%	17.72%
STIP iShares 0-5 Year TIPS Bond ETF	2.04%	6.03%	4.77%	4.63%	-3.02%	5.68%	5.18%	4.89%	0.54%	0.74%

Correlation

The correlation between RGEN and STIP is 0.08, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.08
Correlation (3Y) Calculated over the trailing 3-year period	0.05
Correlation (5Y) Calculated over the trailing 5-year period	0.07
Correlation (10Y) Calculated over the trailing 10-year period	0.04
Correlation (All Time) Calculated using the full available price history since Dec 6, 2010	0.01

Return for Risk

RGEN vs. STIP — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

RGEN

RGEN Risk / Return Rank: 37
RGEN Sharpe Ratio Rank: 39
RGEN Sortino Ratio Rank: 36
RGEN Omega Ratio Rank: 35
RGEN Calmar Ratio Rank: 38
RGEN Martin Ratio Rank: 38

STIP

STIP Risk / Return Rank: 93
STIP Sharpe Ratio Rank: 91
STIP Sortino Ratio Rank: 96
STIP Omega Ratio Rank: 94
STIP Calmar Ratio Rank: 93
STIP Martin Ratio Rank: 94

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

RGEN vs. STIP - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Repligen Corporation (RGEN) and iShares 0-5 Year TIPS Bond ETF (STIP). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	RGEN	STIP	Difference
Sharpe ratio: Return per unit of total volatility	-0.05	3.23	-3.28
Sortino ratio: Return per unit of downside risk	0.25	5.59	-5.33
Omega ratio: Gain probability vs. loss probability	1.03	1.69	-0.67
Calmar ratio: Return relative to maximum drawdown	-0.05	6.76	-6.82
Martin ratio: Return relative to average drawdown	-0.12	26.37	-26.49
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

RGEN vs. STIP - Sharpe Ratio Comparison

The current RGEN Sharpe Ratio is -0.05, which is lower than the STIP Sharpe Ratio of 3.23. The chart below compares the historical Sharpe Ratios of RGEN and STIP, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	RGEN	STIP	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.05	3.23	-3.28
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.15	1.23	-1.38
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.38	1.30	-0.92
Sharpe Ratio (All Time) Calculated using the full available price history	0.09	1.07	-0.98

Drawdowns

RGEN vs. STIP - Drawdown Comparison

The maximum RGEN drawdown since its inception was -98.28%, which is greater than STIP's maximum drawdown of -5.50%. Use the drawdown chart below to compare losses from any high point for RGEN and STIP.

Drawdown Indicators

	RGEN	STIP	Difference
Max Drawdown Largest peak-to-trough decline	-98.28%	-5.50%	-92.78%
Max Drawdown (1Y) Largest decline over 1 year	-40.28%	-0.69%	-39.59%
Max Drawdown (3Y) Largest decline over 3 years	-50.64%	-0.95%	-49.69%
Max Drawdown (5Y) Largest decline over 5 years	-68.27%	-5.50%	-62.77%
Max Drawdown (10Y) Largest decline over 10 years	-68.27%	-5.50%	-62.77%
Current Drawdown Current decline from peak	-62.45%	-0.03%	-62.42%
Average Drawdown Average peak-to-trough decline	-63.36%	-0.99%	-62.37%
Ulcer Index Depth and duration of drawdowns from previous peaks	18.10%	0.18%	+17.92%

Volatility

RGEN vs. STIP - Volatility Comparison

Repligen Corporation (RGEN) has a higher volatility of 15.82% compared to iShares 0-5 Year TIPS Bond ETF (STIP) at 0.40%. This indicates that RGEN's price experiences larger fluctuations and is considered to be riskier than STIP based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	RGEN	STIP	Difference
Volatility (1M) Calculated over the trailing 1-month period	15.82%	0.40%	+15.42%
Volatility (6M) Calculated over the trailing 6-month period	30.52%	0.99%	+29.53%
Volatility (1Y) Calculated over the trailing 1-year period	44.59%	1.46%	+43.13%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	50.40%	2.75%	+47.65%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	45.81%	2.45%	+43.36%

Dividends

RGEN vs. STIP - Dividend Comparison

RGEN has not paid dividends to shareholders, while STIP's dividend yield for the trailing twelve months is around 4.30%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016
RGEN Repligen Corporation	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
STIP iShares 0-5 Year TIPS Bond ETF	4.30%	4.11%	2.62%	2.84%	6.04%	4.15%	1.40%	2.06%	2.44%	1.59%	0.89%

Frequently Asked Questions

Can I hold both RGEN and STIP in my portfolio?

RGEN and STIP have a correlation of 0.08, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, RGEN or STIP?

RGEN has higher volatility (15.82%) compared to STIP (0.40%). In terms of maximum drawdown, RGEN dropped -98.28% vs STIP's -5.50%.

Which has better risk-adjusted returns?

STIP currently has the higher Sharpe Ratio (3.23 vs -0.05), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.