QSI vs. TSM

Last updated Jun 4, 2026

QSI (Quantum-Si incorporated) and TSM (Taiwan Semiconductor Manufacturing Company Limited) are both stocks. QSI operates in Biotechnology (Healthcare), while TSM operates in Semiconductors (Technology). Over the past 3 years, QSI returned -11.03%/yr vs 66.46%/yr for TSM. At a 0.33 correlation, their price movements are largely independent.

Performance

QSI vs. TSM - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Quantum-Si incorporated (QSI) and Taiwan Semiconductor Manufacturing Company Limited (TSM). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, QSI achieves a 8.18% return, which is significantly lower than TSM's 44.10% return.

QSI

• 1D: -4.03%
• 1M: 22.49%
• YTD: 8.18%
• 6M: -12.50%
• 1Y: -32.39%
• 3Y*: -11.03%
• 5Y*: —
• 10Y*: —

TSM

• 1D: -2.24%
• 1M: 8.73%
• YTD: 44.10%
• 6M: 48.60%
• 1Y: 123.66%
• 3Y*: 66.46%
• 5Y*: 31.74%
• 10Y*: 36.20%

*Multi-year figures are annualized to reflect compound growth (CAGR)

QSI vs. TSM - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021
QSI Quantum-Si incorporated	8.18%	-59.26%	34.33%	9.84%	-76.75%	-26.31%
TSM Taiwan Semiconductor Manufacturing Company Limited	44.10%	55.91%	92.58%	42.33%	-36.75%	2.98%

Correlation

The correlation between QSI and TSM is 0.42, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.42
Correlation (3Y) Calculated over the trailing 3-year period	0.33
Correlation (All Time) Calculated using the full available price history since Jun 11, 2021	0.33

Fundamentals

Market Cap QSI : $257.60M TSM : $2.26T
EPS QSI : -$0.51 TSM : $373.98
PS Ratio QSI : 129.62 TSM : 0.55
PB Ratio QSI : 1.28 TSM : 0.38
Total Revenue (TTM) QSI : $1.85M TSM : $4.13T
Gross Profit (TTM) QSI : -$3.71M TSM : $2.55T
EBITDA (TTM) QSI : -$104.05M TSM : $3.14T

Return for Risk

QSI vs. TSM — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

QSI

QSI Risk / Return Rank: 28
QSI Sharpe Ratio Rank: 26
QSI Sortino Ratio Rank: 31
QSI Omega Ratio Rank: 30
QSI Calmar Ratio Rank: 25
QSI Martin Ratio Rank: 28

TSM

TSM Risk / Return Rank: 95
TSM Sharpe Ratio Rank: 96
TSM Sortino Ratio Rank: 95
TSM Omega Ratio Rank: 92
TSM Calmar Ratio Rank: 94
TSM Martin Ratio Rank: 97

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

QSI vs. TSM - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Quantum-Si incorporated (QSI) and Taiwan Semiconductor Manufacturing Company Limited (TSM). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	QSI	TSM	Difference
Sharpe ratio: Return per unit of total volatility	-0.35	3.49	-3.85
Sortino ratio: Return per unit of downside risk	0.03	4.06	-4.03
Omega ratio: Gain probability vs. loss probability	1.00	1.49	-0.49
Calmar ratio: Return relative to maximum drawdown	-0.45	6.86	-7.30
Martin ratio: Return relative to average drawdown	-0.67	24.68	-25.35
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

QSI vs. TSM - Sharpe Ratio Comparison

The current QSI Sharpe Ratio is -0.35, which is lower than the TSM Sharpe Ratio of 3.49. The chart below compares the historical Sharpe Ratios of QSI and TSM, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	QSI	TSM	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.35	3.49	-3.85
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	—	0.86	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	1.06	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.29	0.37	-0.65

Drawdowns

QSI vs. TSM - Drawdown Comparison

The maximum QSI drawdown since its inception was -95.33%, which is greater than TSM's maximum drawdown of -89.08%. Use the drawdown chart below to compare losses from any high point for QSI and TSM.

Drawdown Indicators

	QSI	TSM	Difference
Max Drawdown Largest peak-to-trough decline	-95.33%	-89.08%	-6.25%
Max Drawdown (1Y) Largest decline over 1 year	-72.95%	-18.14%	-54.81%
Max Drawdown (3Y) Largest decline over 3 years	-83.73%	-36.82%	-46.91%
Max Drawdown (5Y) Largest decline over 5 years	—	-56.47%	—
Max Drawdown (10Y) Largest decline over 10 years	—	-56.47%	—
Current Drawdown Current decline from peak	-91.22%	-2.24%	-88.98%
Average Drawdown Average peak-to-trough decline	-79.26%	-42.89%	-36.37%
Ulcer Index Depth and duration of drawdowns from previous peaks	48.36%	5.03%	+43.33%

Volatility

QSI vs. TSM - Volatility Comparison

Quantum-Si incorporated (QSI) has a higher volatility of 22.20% compared to Taiwan Semiconductor Manufacturing Company Limited (TSM) at 11.64%. This indicates that QSI's price experiences larger fluctuations and is considered to be riskier than TSM based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	QSI	TSM	Difference
Volatility (1M) Calculated over the trailing 1-month period	22.20%	11.64%	+10.56%
Volatility (6M) Calculated over the trailing 6-month period	58.29%	27.19%	+31.10%
Volatility (1Y) Calculated over the trailing 1-year period	92.68%	35.61%	+57.07%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	125.41%	37.27%	+88.14%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	125.41%	34.12%	+91.29%

Dividends

QSI vs. TSM - Dividend Comparison

QSI has not paid dividends to shareholders, while TSM's dividend yield for the trailing twelve months is around 0.76%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
QSI Quantum-Si incorporated	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
TSM Taiwan Semiconductor Manufacturing Company Limited	0.76%	1.00%	1.18%	1.78%	2.49%	1.57%	1.56%	3.46%	3.64%	2.32%	2.61%	2.54%

Financials

Frequently Asked Questions

Can I hold both QSI and TSM in my portfolio?

QSI and TSM have a correlation of 0.42, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, QSI or TSM?

QSI has higher volatility (22.20%) compared to TSM (11.64%). In terms of maximum drawdown, QSI dropped -95.33% vs TSM's -89.08%.

Which has better risk-adjusted returns?

TSM currently has the higher Sharpe Ratio (3.49 vs -0.35), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.