PTGX vs. AXGN
PTGX (Protagonist Therapeutics Inc) and AXGN (AxoGen, Inc.) are both stocks. Both are in the Healthcare sector — PTGX in Biotechnology, AXGN in Medical Devices. Over the past 5 years, PTGX returned 23.69%/yr vs 13.66%/yr for AXGN. At a 0.23 correlation, their price movements are largely independent.
Performance
PTGX vs. AXGN - Performance Comparison
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Returns By Period
In the year-to-date period, PTGX achieves a 48.72% return, which is significantly higher than AXGN's 20.65% return.
PTGX
- 1D
- -1.16%
- 1M
- 18.32%
- 6M
- 61.86%
- YTD
- 48.72%
- 1Y
- 145.08%
- 3Y*
- 82.84%
- 5Y*
- 23.69%
- 10Y*
- —
AXGN
- 1D
- -2.69%
- 1M
- -8.16%
- 6M
- 25.17%
- YTD
- 20.65%
- 1Y
- 232.13%
- 3Y*
- 64.82%
- 5Y*
- 13.66%
- 10Y*
- 19.02%
PTGX vs. AXGN - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
PTGX Protagonist Therapeutics Inc | 48.72% | 126.27% | 68.34% | 110.17% | -68.10% | 69.64% | 185.96% | 4.75% | -67.64% | -5.41% |
AXGN AxoGen, Inc. | 20.65% | 98.60% | 141.29% | -31.56% | 6.51% | -47.65% | 0.06% | -12.43% | -27.81% | 214.44% |
Correlation
The correlation between PTGX and AXGN is 0.12, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.12 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.22 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.28 |
Correlation (All Time) Calculated using the full available price history since Aug 11, 2016 | 0.23 |
The correlation between PTGX and AXGN shifts across timeframes, from 0.12 (1 year) to 0.28 (5 years), reflecting how their relationship changes across market environments.
Fundamentals
PTGX:
$8.35B
AXGN:
$2.10B
PTGX:
-$1.74
AXGN:
-$0.65
PTGX:
484.08
AXGN:
7.98
PTGX:
13.97
AXGN:
8.32
PTGX:
$17.70M
AXGN:
$238.11M
PTGX:
$17.32M
AXGN:
$178.61M
PTGX:
-$127.71M
AXGN:
$5.69M
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Return for Risk
PTGX vs. AXGN — Risk / Return Rank
PTGX
AXGN
PTGX vs. AXGN - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Protagonist Therapeutics Inc (PTGX) and AxoGen, Inc. (AXGN). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| PTGX | AXGN | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -1.38 | ||
| Sortino ratioReturn per unit of downside risk | -0.62 | ||
| Omega ratioGain probability vs. loss probability | 1.48 | 1.55 | -0.07 |
| Calmar ratioReturn relative to maximum drawdown | 8.91 | 12.11 | -3.20 |
| Martin ratioReturn relative to average drawdown | 20.77 | 40.79 | -20.02 |
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Drawdowns
PTGX vs. AXGN - Drawdown Comparison
The maximum PTGX drawdown since its inception was -85.79%, smaller than the maximum AXGN drawdown of -98.49%. Use the drawdown chart below to compare losses from any high point for PTGX and AXGN.
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Drawdown Indicators
| PTGX | AXGN | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -85.79% | -98.49% | +12.70% |
Max Drawdown (1Y)Largest decline over 1 year | -16.38% | -19.30% | +2.92% |
Max Drawdown (3Y)Largest decline over 3 years | -33.88% | -59.66% | +25.78% |
Max Drawdown (5Y)Largest decline over 5 years | -85.79% | -82.29% | -3.50% |
Max Drawdown (10Y)Largest decline over 10 years | — | -93.54% | — |
Current DrawdownCurrent decline from peak | -7.78% | -29.36% | +21.58% |
Average DrawdownAverage peak-to-trough decline | -40.37% | -64.77% | +24.40% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 7.01% | 5.72% | +1.29% |
Volatility
PTGX vs. AXGN - Volatility Comparison
The current volatility for Protagonist Therapeutics Inc (PTGX) is 11.70%, while AxoGen, Inc. (AXGN) has a volatility of 14.73%. This indicates that PTGX experiences smaller price fluctuations and is considered to be less risky than AXGN based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| PTGX | AXGN | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 11.70% | 14.73% | -3.03% |
Volatility (6M)Calculated over the trailing 6-month period | 30.59% | 34.87% | -4.28% |
Volatility (1Y)Calculated over the trailing 1-year period | 51.11% | 55.16% | -4.05% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 85.25% | 64.27% | +20.98% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 90.51% | 62.15% | +28.36% |
Dividends
PTGX vs. AXGN - Dividend Comparison
Neither PTGX nor AXGN has paid dividends to shareholders.
Financials
PTGX vs. AXGN - Financials Comparison
This section allows you to compare key financial metrics between Protagonist Therapeutics Inc and AxoGen, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
Frequently Asked Questions
PTGX and AXGN have a correlation of 0.12, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
AXGN has higher volatility (14.73%) compared to PTGX (11.70%). In terms of maximum drawdown, PTGX dropped -85.79% vs AXGN's -98.49%.
AXGN currently has the higher Sharpe Ratio (4.25 vs 2.86), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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