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Protagonist Therapeutics Inc (PTGX)
Performance
Risk-Adjusted Performance
Dividends
Drawdowns
Volatility
Financials

Company Info

ISIN

US74366E1029

CUSIP

74366E102

IPO Date

Aug 11, 2016

Highlights

Market Cap

$2.95B

EPS (TTM)

$0.78

PE Ratio

61.00

Total Revenue (TTM)

$207.80M

Gross Profit (TTM)

$206.31M

EBITDA (TTM)

$28.65M

Year Range

$28.36 - $60.60

Target Price

$68.70

Short %

10.23%

Short Ratio

5.50

Share Price Chart


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Compare to other instruments

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Protagonist Therapeutics Inc

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Performance

Performance Chart


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S&P 500

Returns By Period

Protagonist Therapeutics Inc (PTGX) returned 22.98% year-to-date (YTD) and 71.31% over the past 12 months.


PTGX

YTD

22.98%

1M

3.60%

6M

8.38%

1Y

71.31%

3Y*

75.65%

5Y*

23.49%

10Y*

N/A

^GSPC (Benchmark)

YTD

0.51%

1M

6.15%

6M

-2.00%

1Y

12.92%

3Y*

12.68%

5Y*

14.19%

10Y*

10.85%

*Annualized

Monthly Returns

The table below presents the monthly returns of PTGX, with color gradation from worst to best to easily spot seasonal factors. Returns are adjusted for dividends.


JanFebMarAprMayJunJulAugSepOctNovDecTotal
2025-2.07%-0.56%28.65%-5.25%3.60%22.98%
20249.07%21.47%-4.77%-13.20%12.11%23.09%8.05%14.56%4.92%1.87%-4.45%-11.87%68.34%
202321.81%22.05%41.80%-1.74%15.35%5.95%-29.76%2.16%-15.84%-12.83%25.24%25.92%110.17%
2022-14.36%-17.10%-2.47%-61.61%-3.63%-9.70%25.79%-12.36%-3.33%-3.91%-2.35%37.93%-68.10%
20212.73%13.81%9.89%11.74%21.32%27.83%10.14%-1.88%-63.46%75.85%7.89%1.73%69.64%
20207.09%3.31%-9.49%-4.39%144.89%6.84%-10.93%42.40%-12.72%-3.07%27.49%-16.56%185.96%
201921.10%-1.60%56.73%-17.82%-2.61%20.38%-9.00%18.24%-7.83%11.99%-35.32%-18.97%4.75%
20189.90%-25.85%-49.32%0.58%-15.74%-7.69%2.98%39.16%6.85%-22.35%-19.02%4.02%-67.64%
2017-17.96%-23.17%-7.58%-21.00%10.38%1.25%7.78%33.96%8.21%-15.28%30.26%6.67%-5.41%
20162.65%75.94%-11.03%32.71%-11.86%87.95%
Go deeper with the Portfolio Analysis tool — backtest performance, assess risk, compare to benchmarks, and more

Risk-Adjusted Performance

Risk-Adjusted Performance Rank

With an overall rank of 84, PTGX is among the top 16% of stocks on our website when it comes to balancing risk and reward. Below is a breakdown of how it compares using common performance measures.


The Risk-Adjusted Performance Rank of PTGX is 8484
Overall Rank
The Sharpe Ratio Rank of PTGX is 8484
Sharpe Ratio Rank
The Sortino Ratio Rank of PTGX is 8888
Sortino Ratio Rank
The Omega Ratio Rank of PTGX is 8282
Omega Ratio Rank
The Calmar Ratio Rank of PTGX is 8787
Calmar Ratio Rank
The Martin Ratio Rank of PTGX is 8181
Martin Ratio Rank
The risk-adjusted ranks indicate the investment's position relative to the market. A rank closer to 100 signifies top-performing investments, while a rank closer to 0 might suggest underperformance, based on the selected ratio. The values are calculated based on the past 12 months of returns.

Risk-Adjusted Performance Indicators

The charts below present risk-adjusted performance metrics for Protagonist Therapeutics Inc (PTGX) and compare them to a chosen benchmark (^GSPC). These indicators evaluate an investment's returns against its associated risks.


The Sharpe ratio helps investors understand how much return they're getting for the level of risk taken. A higher Sharpe ratio indicates better risk-adjusted performance, meaning more reward for each unit of risk.

Protagonist Therapeutics Inc Sharpe ratios as of May 31, 2025 (values are recalculated daily):

  • 1-Year: 1.11
  • 5-Year: 0.27
  • All Time: 0.18

These values reflect how efficiently the investment has delivered returns relative to its volatility over different time periods. All figures are annualized and based on daily total returns (including price changes and dividends).

The chart below shows the rolling Sharpe ratio of Protagonist Therapeutics Inc compared to the selected benchmark. This view highlights how the investment's risk-adjusted performance has changed over time.


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Go to the full Sharpe Ratio tool to analyze any stock or portfolio. Customize time frames, set your own risk-free rate, and more

Dividends

Dividend History


Protagonist Therapeutics Inc doesn't pay dividends

Drawdowns

Drawdowns Chart

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.


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Worst Drawdowns

The table below displays the maximum drawdowns of the Protagonist Therapeutics Inc. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the Protagonist Therapeutics Inc was 85.79%, occurring on Jun 13, 2022. Recovery took 686 trading sessions.

The current Protagonist Therapeutics Inc drawdown is 20.57%.


Depth

Start

To Bottom

Bottom

To Recover

End

Total

-85.79%Sep 2, 2021196Jun 13, 2022686Mar 10, 2025882
-82.13%Dec 6, 2016753Dec 3, 2019302Feb 16, 20211055
-31.58%Mar 12, 202522Apr 10, 2025
-20.33%Oct 18, 201611Nov 1, 20167Nov 10, 201618
-19.04%Mar 22, 20216Mar 29, 202135May 18, 202141
Go to the full Drawdowns tool for more analysis options, including inflation-adjusted drawdowns, and more

Volatility

Volatility Chart

The chart below shows the rolling one-month volatility.


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Financials

Financial Performance

The chart below illustrates the trends in the financial health of Protagonist Therapeutics Inc over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.


Annual
Quarterly

0.0

Earnings Per Share

The chart presents the Earnings Per Share (EPS) performance of Protagonist Therapeutics Inc, comparing actual results with analytics estimates. In the past quarter, the company did not meet analyst expectations for EPS, resulting in a surprise of -272.7%.


-1.000.001.002.003.0020212022202320242025
-0.19
0.11
Actual
Estimate

Valuation

The Valuation section provides an overview of how Protagonist Therapeutics Inc is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.


PE Ratio

The chart displays the Price-to-Earnings (P/E) ratio for PTGX, comparing it with other companies in the Biotechnology industry. Currently, PTGX has a P/E ratio of 61.0. This P/E ratio is significantly higher than those of industry peers. This could indicate that the stock is overvalued or that investors expect strong future growth.

PEG Ratio

The chart shows the Price/Earnings to Growth (PEG) ratio for PTGX compared to other companies in the Biotechnology industry. PTGX currently has a PEG ratio of 0.0. This PEG ratio is low compared to industry peers, which could indicate the stock is undervalued relative to its expected growth.

PS Ratio

This chart shows the Price-to-Sales (P/S) ratio for PTGX relative to other companies in the Biotechnology industry. Currently, PTGX has a P/S ratio of 14.2. This P/S ratio falls within the average range for the industry, suggesting the stock is fairly valued based on its revenue.

PB Ratio

The chart illustrates the Price-to-Book (P/B) ratio for PTGX in comparison with other companies in the Biotechnology industry. Currently, PTGX has a P/B value of 4.3. This P/B ratio is in line with the industry average, suggesting the stock is valued fairly in relation to its book value.

Income Statement



TTM
Revenue

Total Revenue

Cost Of Revenue

Gross Profit

Operating Expenses

Selling, General & Admin Expenses

R&D Expenses

Depreciation And Amortization

Total Operating Expenses

Income

Income Before Tax

Operating Income

EBITDA

EBIT

Earnings From Continuing Operations

Net Income

Income Tax Expense

Other Non-Operating Income (Expenses)

Extraordinary Items

Discontinued Operations

Effect Of Accounting Charges

Non Recurring

Minority Interest

Other Items

Interest Income

Interest Expense

Net Interest Income

Values in undefined except per share items