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PSTV vs. TNYA
Performance
Return for Risk
Drawdowns
Volatility
Dividends
Financials

Performance

PSTV vs. TNYA - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Plus Therapeutics Inc (PSTV) and Tenaya Therapeutics, Inc. (TNYA). The values are adjusted to include any dividend payments, if applicable.

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Returns By Period

In the year-to-date period, PSTV achieves a -68.14% return, which is significantly lower than TNYA's 2.04% return.


PSTV

1D
2.51%
1M
-38.09%
YTD
-68.14%
6M
-70.27%
1Y
-11.45%
3Y*
-62.09%
5Y*
-67.02%
10Y*
-68.14%

TNYA

1D
3.71%
1M
-6.02%
YTD
2.04%
6M
3.24%
1Y
29.97%
3Y*
-49.80%
5Y*
10Y*
*Multi-year figures are annualized to reflect compound growth (CAGR)

PSTV vs. TNYA - Yearly Performance Comparison


2026 (YTD)20252024202320222021
PSTV
Plus Therapeutics Inc
-68.14%-55.45%-34.29%-63.19%-69.81%-46.15%
TNYA
Tenaya Therapeutics, Inc.
2.04%-50.24%-55.86%61.19%-89.39%-2.82%

Correlation

The correlation between PSTV and TNYA is 0.22, which is low. Their price movements are largely independent, making them effective diversification partners.


Correlation
Correlation (1Y)
Calculated over the trailing 1-year period

0.22

Correlation (3Y)
Calculated over the trailing 3-year period

0.16

Correlation (All Time)
Calculated using the full available price history since Jul 30, 2021

0.17

Fundamentals

Market Cap

PSTV:

$27.12M

TNYA:

$157.46M

EPS

PSTV:

-$4.87

TNYA:

-$0.48

PS Ratio

PSTV:

2.41

TNYA:

561.43

PB Ratio

PSTV:

2.27

TNYA:

1.48

Total Revenue (TTM)

PSTV:

$4.15M

TNYA:

$225.00K

Gross Profit (TTM)

PSTV:

$3.89M

TNYA:

$0.00

EBITDA (TTM)

PSTV:

-$1.39M

TNYA:

-$78.62M

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Return for Risk

PSTV vs. TNYA — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

PSTV
PSTV Risk / Return Rank: 4646
Overall Rank
PSTV Sharpe Ratio Rank: 3939
Sharpe Ratio Rank
PSTV Sortino Ratio Rank: 5757
Sortino Ratio Rank
PSTV Omega Ratio Rank: 5555
Omega Ratio Rank
PSTV Calmar Ratio Rank: 3939
Calmar Ratio Rank
PSTV Martin Ratio Rank: 3939
Martin Ratio Rank

TNYA
TNYA Risk / Return Rank: 5555
Overall Rank
TNYA Sharpe Ratio Rank: 5252
Sharpe Ratio Rank
TNYA Sortino Ratio Rank: 6262
Sortino Ratio Rank
TNYA Omega Ratio Rank: 5959
Omega Ratio Rank
TNYA Calmar Ratio Rank: 5252
Calmar Ratio Rank
TNYA Martin Ratio Rank: 5050
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

PSTV vs. TNYA - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Plus Therapeutics Inc (PSTV) and Tenaya Therapeutics, Inc. (TNYA). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.


PSTVTNYADifference
Sharpe ratioReturn per unit of total volatility

-0.35

Sortino ratioReturn per unit of downside risk

-0.19

Omega ratioGain probability vs. loss probability

1.13

1.15

-0.03

Calmar ratioReturn relative to maximum drawdown

-0.13

0.41

-0.54

Martin ratioReturn relative to average drawdown

-0.21

0.62

-0.83

PSTV vs. TNYA - Sharpe Ratio Comparison

The current PSTV Sharpe Ratio is -0.08, which is lower than the TNYA Sharpe Ratio of 0.27. The chart below compares the historical Sharpe Ratios of PSTV and TNYA, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.


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Drawdowns

PSTV vs. TNYA - Drawdown Comparison

The maximum PSTV drawdown since its inception was -100.00%, roughly equal to the maximum TNYA drawdown of -98.69%. Use the drawdown chart below to compare losses from any high point for PSTV and TNYA.


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Drawdown Indicators


PSTVTNYADifference

Max Drawdown

Largest peak-to-trough decline

-100.00%

-98.69%

-1.31%

Max Drawdown (1Y)

Largest decline over 1 year

-86.87%

-73.81%

-13.06%

Max Drawdown (3Y)

Largest decline over 3 years

-96.30%

-94.30%

-2.00%

Max Drawdown (5Y)

Largest decline over 5 years

-99.72%

Max Drawdown (10Y)

Largest decline over 10 years

-100.00%

Current Drawdown

Current decline from peak

-100.00%

-97.55%

-2.45%

Average Drawdown

Average peak-to-trough decline

-79.52%

-82.23%

+2.71%

Ulcer Index

Depth and duration of drawdowns from previous peaks

53.48%

48.71%

+4.77%

Volatility

PSTV vs. TNYA - Volatility Comparison

The current volatility for Plus Therapeutics Inc (PSTV) is 17.29%, while Tenaya Therapeutics, Inc. (TNYA) has a volatility of 19.37%. This indicates that PSTV experiences smaller price fluctuations and is considered to be less risky than TNYA based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


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Volatility by Period


PSTVTNYADifference

Volatility (1M)

Calculated over the trailing 1-month period

17.29%

19.37%

-2.08%

Volatility (6M)

Calculated over the trailing 6-month period

87.33%

70.37%

+16.96%

Volatility (1Y)

Calculated over the trailing 1-year period

150.10%

111.36%

+38.74%

Volatility (5Y)

Calculated over the trailing 5-year period, annualized

198.10%

109.06%

+89.04%

Volatility (10Y)

Calculated over the trailing 10-year period, annualized

184.30%

109.06%

+75.24%

Dividends

PSTV vs. TNYA - Dividend Comparison

Neither PSTV nor TNYA has paid dividends to shareholders.


Tickers have no history of dividend payments

Financials

PSTV vs. TNYA - Financials Comparison

This section allows you to compare key financial metrics between Plus Therapeutics Inc and Tenaya Therapeutics, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


0.00500.00K1.00M1.50M2.00M202220232024202520260
225.00K
(PSTV) Total Revenue
(TNYA) Total Revenue
Values in USD except per share items

Frequently Asked Questions


PSTV and TNYA have a correlation of 0.22, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

TNYA has higher volatility (19.37%) compared to PSTV (17.29%). In terms of maximum drawdown, PSTV dropped -100.00% vs TNYA's -98.69%.

TNYA currently has the higher Sharpe Ratio (0.27 vs -0.08), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.

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