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Plus Therapeutics Inc (PSTV)
Performance
Return for Risk
Dividends
Drawdowns
Volatility
Financials

Company Info

ISIN
US72941H4002
CUSIP
72941H103
IPO Date
Nov 16, 2000

Highlights

Market Cap
$12.65B
Enterprise Value
$12.64B
EPS (TTM)
-$0.00
Year Range
$0.16 - $1.22
Target Price
$1.00
ROA (TTM)
-137.13%
ROE (TTM)
-560.21%

Share Price Chart


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Plus Therapeutics Inc

Performance

Performance Chart

The chart shows the growth of an initial investment of $10,000 in Plus Therapeutics Inc, comparing it to the performance of the S&P 500 index or another benchmark. All prices have been adjusted for splits and dividends.


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S&P 500 Index

Returns By Period

Plus Therapeutics Inc (PSTV) has returned -68.26% so far this year and -82.89% over the past 12 months. Over the last ten years, PSTV has returned -69.69% per year, falling short of the S&P 500 Index benchmark, which averaged 12.16% annually.


Plus Therapeutics Inc

1D
-24.23%
1M
-46.28%
YTD
-68.26%
6M
-76.22%
1Y
-82.89%
3Y*
-66.56%
5Y*
-66.21%
10Y*
-69.69%

Benchmark (S&P 500 Index)

1D
2.91%
1M
-5.09%
YTD
-4.63%
6M
-2.39%
1Y
16.33%
3Y*
16.69%
5Y*
10.18%
10Y*
12.16%
*Multi-year figures are annualized to reflect compound growth (CAGR)

Monthly Returns

Based on dividend-adjusted daily data since Nov 16, 2000, PSTV's average daily return is 0.00%, while the average monthly return is -1.90%.

Historically, 40% of months were positive and 60% were negative. The best month was Feb 2015 with a return of +133.3%, while the worst month was Sep 2019 at -77.7%. The longest winning streak lasted 4 consecutive months, and the longest losing streak was 11 months.

On a daily basis, PSTV closed higher 39% of trading days. The best single day was Mar 6, 2025 with a return of +311.4%, while the worst single day was Jul 24, 2017 at -56.8%.


JanFebMarAprMayJunJulAugSepOctNovDecTotal
2026-55.48%32.70%-46.28%-68.26%
20257.83%-41.53%31.05%-24.29%-60.11%21.23%38.87%-5.59%49.93%-20.58%12.34%-16.02%-55.45%
202414.85%-3.48%-6.96%-3.57%26.98%-33.48%22.45%-20.56%2.10%-9.93%-2.66%-10.16%-34.29%
202336.69%-21.49%-14.76%-10.41%3.16%-49.75%21.78%13.41%-51.97%-8.96%39.34%2.95%-63.19%
2022-10.10%10.17%-3.85%-33.00%-16.48%-3.48%-8.37%69.61%-46.99%5.62%-14.32%-21.28%-69.81%
202119.31%18.26%-15.79%-5.00%3.95%8.02%-25.78%2.63%-2.05%-0.52%-21.05%-30.00%-48.02%

Benchmark Metrics

Plus Therapeutics Inc has an annualized alpha of -6.58%, beta of 0.95, and R² of 0.02 versus S&P 500 Index. Calculated based on daily prices since November 17, 2000.

  • This stock participated in 185.43% of S&P 500 Index downside but only -58.05% of its upside — more exposed to losses than it benefited from rallies.
  • R² of 0.02 means this stock moves largely independently of S&P 500 Index — capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.

Alpha
-6.58%
Beta
0.95
0.02
Upside Capture
-58.05%
Downside Capture
185.43%

Return for Risk

Risk / Return Rank

PSTV ranks 13 for risk / return — in the bottom 13% of stocks on our site. This means you're taking on significantly more risk than the returns justify. Consider whether the potential upside is worth the volatility, or explore alternatives with better risk / return profiles.


PSTV Risk / Return Rank: 1313
Overall Rank
PSTV Sharpe Ratio Rank: 1818
Sharpe Ratio Rank
PSTV Sortino Ratio Rank: 1919
Sortino Ratio Rank
PSTV Omega Ratio Rank: 2020
Omega Ratio Rank
PSTV Calmar Ratio Rank: 00
Calmar Ratio Rank
PSTV Martin Ratio Rank: 88
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

Return / Risk — by metrics

The table below present risk-adjusted performance metrics for Plus Therapeutics Inc (PSTV) and compare them to a chosen benchmark (S&P 500 Index).


PSTVBenchmarkDifference

Sharpe ratio

Return per unit of total volatility

-0.51

0.90

-1.40

Sortino ratio

Return per unit of downside risk

-0.48

1.39

-1.86

Omega ratio

Gain probability vs. loss probability

0.94

1.21

-0.27

Calmar ratio

Return relative to maximum drawdown

-1.02

1.40

-2.42

Martin ratio

Return relative to average drawdown

-1.55

6.61

-8.15

Explore PSTV risk-adjusted metrics in detail

Dive deeper into individual metrics with historical trends, benchmark comparisons, and performance across different time periods.

Dividends

Dividend History


Plus Therapeutics Inc doesn't pay dividends

Drawdowns

Drawdowns Chart

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.


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Worst Drawdowns

The table below displays the maximum drawdowns of the Plus Therapeutics Inc. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the Plus Therapeutics Inc was 100.00%, occurring on Mar 31, 2026. The portfolio has not yet recovered.

The current Plus Therapeutics Inc drawdown is 100.00%.


Depth

Start

To Bottom

Bottom

To Recover

End

Total

-100%Jan 3, 20016347Mar 31, 2026

Volatility

Volatility Chart

The chart below shows the rolling one-month volatility.


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Financials

Financial Performance

The chart below illustrates the trends in the financial health of Plus Therapeutics Inc over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.


Annual
Quarterly

0.0

Valuation

The Valuation section provides an overview of how Plus Therapeutics Inc is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.


PB Ratio

The chart illustrates the Price-to-Book (P/B) ratio for PSTV in comparison with other companies in the Biotechnology industry. Currently, PSTV has a P/B value of 3,165.9. This P/B ratio is higher than most companies in the industry. It may suggest the stock is overvalued or that investors expect the company to generate high returns on its assets.

Income Statement



TTM
Revenue

Total Revenue

Cost Of Revenue

Gross Profit

Operating Expenses

Selling, General & Admin Expenses

R&D Expenses

Depreciation And Amortization

Total Operating Expenses

Income

Income Before Tax

Operating Income

EBITDA

EBIT

Earnings From Continuing Operations

Net Income

Income Tax Expense

Other Non-Operating Income (Expenses)

Extraordinary Items

Discontinued Operations

Effect Of Accounting Charges

Non Recurring

Minority Interest

Other Items

Interest Income

Interest Expense

Net Interest Income

Values in undefined except per share items