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PROK vs. CRBU
Performance
Return for Risk
Drawdowns
Volatility
Dividends
Financials

Performance

PROK vs. CRBU - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in ProKidney Corp. (PROK) and Caribou Biosciences, Inc. (CRBU). The values are adjusted to include any dividend payments, if applicable.

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Returns By Period

In the year-to-date period, PROK achieves a -27.68% return, which is significantly lower than CRBU's 3.77% return.


PROK

1D
0.62%
1M
-7.43%
6M
-29.26%
YTD
-27.68%
1Y
-53.98%
3Y*
-47.80%
5Y*
10Y*

CRBU

1D
-0.60%
1M
0.61%
6M
13.01%
YTD
3.77%
1Y
-9.84%
3Y*
-37.96%
5Y*
10Y*
*Multi-year figures are annualized to reflect compound growth (CAGR)

PROK vs. CRBU - Yearly Performance Comparison


2026 (YTD)2025202420232022
PROK
ProKidney Corp.
-27.68%32.54%-5.06%-74.05%-27.02%
CRBU
Caribou Biosciences, Inc.
3.77%0.00%-72.25%-8.76%-6.13%

Correlation

The correlation between PROK and CRBU is 0.37, which is low. Their price movements are largely independent, making them effective diversification partners.


Correlation
Correlation (1Y)
Calculated over the trailing 1-year period

0.37

Correlation (3Y)
Calculated over the trailing 3-year period

0.33

Correlation (All Time)
Calculated using the full available price history since Jul 12, 2022

0.28

Fundamentals

Market Cap

PROK:

$544.73M

CRBU:

$163.65M

EPS

PROK:

-$0.00

CRBU:

-$1.41

PS Ratio

PROK:

86.37K

CRBU:

17.72

PB Ratio

PROK:

873.87

CRBU:

1.55

Total Revenue (TTM)

PROK:

$889.00K

CRBU:

$8.81M

Gross Profit (TTM)

PROK:

-$2.18M

CRBU:

$7.49M

EBITDA (TTM)

PROK:

-$112.46M

CRBU:

-$115.23M

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Return for Risk

PROK vs. CRBU — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

PROK
PROK Risk / Return Rank: 1212
Overall Rank
PROK Sharpe Ratio Rank: 1717
Sharpe Ratio Rank
PROK Sortino Ratio Rank: 1818
Sortino Ratio Rank
PROK Omega Ratio Rank: 1919
Omega Ratio Rank
PROK Calmar Ratio Rank: 00
Calmar Ratio Rank
PROK Martin Ratio Rank: 44
Martin Ratio Rank

CRBU
CRBU Risk / Return Rank: 4040
Overall Rank
CRBU Sharpe Ratio Rank: 3939
Sharpe Ratio Rank
CRBU Sortino Ratio Rank: 4444
Sortino Ratio Rank
CRBU Omega Ratio Rank: 4242
Omega Ratio Rank
CRBU Calmar Ratio Rank: 3939
Calmar Ratio Rank
CRBU Martin Ratio Rank: 3939
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

PROK vs. CRBU - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for ProKidney Corp. (PROK) and Caribou Biosciences, Inc. (CRBU). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.


PROKCRBUDifference
Sharpe ratioReturn per unit of total volatility

-0.50

Sortino ratioReturn per unit of downside risk

-1.10

Omega ratioGain probability vs. loss probability

0.92

1.04

-0.12

Calmar ratioReturn relative to maximum drawdown

-1.02

-0.19

-0.83

Martin ratioReturn relative to average drawdown

-1.59

-0.31

-1.27

PROK vs. CRBU - Sharpe Ratio Comparison

The current PROK Sharpe Ratio is -0.63, which is lower than the CRBU Sharpe Ratio of -0.13. The chart below compares the historical Sharpe Ratios of PROK and CRBU, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.


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Drawdowns

PROK vs. CRBU - Drawdown Comparison

The maximum PROK drawdown since its inception was -96.29%, roughly equal to the maximum CRBU drawdown of -97.58%. Use the drawdown chart below to compare losses from any high point for PROK and CRBU.


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Drawdown Indicators


PROKCRBUDifference

Max Drawdown

Largest peak-to-trough decline

-96.29%

-97.58%

+1.29%

Max Drawdown (1Y)

Largest decline over 1 year

-53.03%

-51.06%

-1.97%

Max Drawdown (3Y)

Largest decline over 3 years

-96.09%

-91.12%

-4.97%

Current Drawdown

Current decline from peak

-88.24%

-94.55%

+6.31%

Average Drawdown

Average peak-to-trough decline

-65.73%

-79.59%

+13.86%

Ulcer Index

Depth and duration of drawdowns from previous peaks

37.78%

31.65%

+6.13%

Volatility

PROK vs. CRBU - Volatility Comparison

ProKidney Corp. (PROK) has a higher volatility of 21.51% compared to Caribou Biosciences, Inc. (CRBU) at 15.29%. This indicates that PROK's price experiences larger fluctuations and is considered to be riskier than CRBU based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


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Volatility by Period


PROKCRBUDifference

Volatility (1M)

Calculated over the trailing 1-month period

21.51%

15.29%

+6.22%

Volatility (6M)

Calculated over the trailing 6-month period

49.00%

50.46%

-1.46%

Volatility (1Y)

Calculated over the trailing 1-year period

86.54%

77.91%

+8.63%

Volatility (5Y)

Calculated over the trailing 5-year period, annualized

280.69%

86.28%

+194.41%

Volatility (10Y)

Calculated over the trailing 10-year period, annualized

280.69%

86.28%

+194.41%

Dividends

PROK vs. CRBU - Dividend Comparison

Neither PROK nor CRBU has paid dividends to shareholders.


Tickers have no history of dividend payments

Financials

PROK vs. CRBU - Financials Comparison

This section allows you to compare key financial metrics between ProKidney Corp. and Caribou Biosciences, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


0.005.00M10.00M15.00M20.00MJulyOctober2022AprilJulyOctober2023AprilJulyOctober2024AprilJulyOctober2025AprilJulyOctober2026
226.00K
0
(PROK) Total Revenue
(CRBU) Total Revenue
Values in USD except per share items

Frequently Asked Questions


PROK and CRBU have a correlation of 0.37, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

PROK has higher volatility (21.51%) compared to CRBU (15.29%). In terms of maximum drawdown, PROK dropped -96.29% vs CRBU's -97.58%.

CRBU currently has the higher Sharpe Ratio (-0.13 vs -0.63), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.

Portfolio Optimizer

Find the right allocation for PROK and CRBU

Add both to a portfolio and optimize allocations for your target — whether that's maximizing returns, minimizing drawdowns, or balancing risk across holdings.

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