PRLD vs. VT

Last updated Jun 4, 2026

PRLD (Prelude Therapeutics Incorporated) is a stock, while VT (Vanguard Total World Stock ETF) is Global Equities fund tracking the FTSE Global All Cap Index. Over the past 5 years, PRLD returned -34.33%/yr vs 10.99%/yr for VT. At a 0.29 correlation, their price movements are largely independent.

Performance

PRLD vs. VT - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Prelude Therapeutics Incorporated (PRLD) and Vanguard Total World Stock ETF (VT). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, PRLD achieves a 26.21% return, which is significantly higher than VT's 12.24% return.

PRLD

• 1D: 4.57%
• 1M: -22.78%
• YTD: 26.21%
• 6M: 165.22%
• 1Y: 291.32%
• 3Y*: -13.68%
• 5Y*: -34.33%
• 10Y*: —

VT

• 1D: -0.88%
• 1M: 4.91%
• YTD: 12.24%
• 6M: 13.14%
• 1Y: 29.24%
• 3Y*: 20.93%
• 5Y*: 10.99%
• 10Y*: 12.74%

*Multi-year figures are annualized to reflect compound growth (CAGR)

PRLD vs. VT - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020
PRLD Prelude Therapeutics Incorporated	26.21%	127.45%	-70.14%	-29.30%	-51.49%	-82.60%	173.09%
VT Vanguard Total World Stock ETF	12.24%	22.43%	16.49%	22.02%	-18.00%	18.27%	17.45%

Correlation

The correlation between PRLD and VT is 0.19, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.19
Correlation (3Y) Calculated over the trailing 3-year period	0.28
Correlation (5Y) Calculated over the trailing 5-year period	0.30
Correlation (All Time) Calculated using the full available price history since Sep 28, 2020	0.29

The correlation between PRLD and VT shifts across timeframes, from 0.19 (1 year) to 0.30 (5 years), reflecting how their relationship changes across market environments.

Return for Risk

PRLD vs. VT — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

PRLD

PRLD Risk / Return Rank: 87
PRLD Sharpe Ratio Rank: 81
PRLD Sortino Ratio Rank: 90
PRLD Omega Ratio Rank: 91
PRLD Calmar Ratio Rank: 89
PRLD Martin Ratio Rank: 85

VT

VT Risk / Return Rank: 67
VT Sharpe Ratio Rank: 68
VT Sortino Ratio Rank: 68
VT Omega Ratio Rank: 67
VT Calmar Ratio Rank: 60
VT Martin Ratio Rank: 71

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

PRLD vs. VT - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Prelude Therapeutics Incorporated (PRLD) and Vanguard Total World Stock ETF (VT). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	PRLD	VT	Difference
Sharpe ratio: Return per unit of total volatility	1.48	2.31	-0.84
Sortino ratio: Return per unit of downside risk	3.22	3.20	+0.02
Omega ratio: Gain probability vs. loss probability	1.45	1.42	+0.04
Calmar ratio: Return relative to maximum drawdown	4.19	3.04	+1.15
Martin ratio: Return relative to average drawdown	8.98	13.53	-4.55
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

PRLD vs. VT - Sharpe Ratio Comparison

The current PRLD Sharpe Ratio is 1.48, which is lower than the VT Sharpe Ratio of 2.31. The chart below compares the historical Sharpe Ratios of PRLD and VT, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	PRLD	VT	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.48	2.31	-0.84
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.28	0.69	-0.96
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	0.74	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.24	0.44	-0.68

Drawdowns

PRLD vs. VT - Drawdown Comparison

The maximum PRLD drawdown since its inception was -99.33%, which is greater than VT's maximum drawdown of -50.27%. Use the drawdown chart below to compare losses from any high point for PRLD and VT.

Drawdown Indicators

	PRLD	VT	Difference
Max Drawdown Largest peak-to-trough decline	-99.33%	-50.27%	-49.06%
Max Drawdown (1Y) Largest decline over 1 year	-70.10%	-9.67%	-60.43%
Max Drawdown (3Y) Largest decline over 3 years	-90.42%	-16.51%	-73.91%
Max Drawdown (5Y) Largest decline over 5 years	-98.42%	-26.38%	-72.04%
Max Drawdown (10Y) Largest decline over 10 years	—	-34.24%	—
Current Drawdown Current decline from peak	-96.01%	-0.88%	-95.13%
Average Drawdown Average peak-to-trough decline	-85.17%	-7.02%	-78.15%
Ulcer Index Depth and duration of drawdowns from previous peaks	32.62%	2.17%	+30.45%

Volatility

PRLD vs. VT - Volatility Comparison

Prelude Therapeutics Incorporated (PRLD) has a higher volatility of 17.75% compared to Vanguard Total World Stock ETF (VT) at 3.83%. This indicates that PRLD's price experiences larger fluctuations and is considered to be riskier than VT based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	PRLD	VT	Difference
Volatility (1M) Calculated over the trailing 1-month period	17.75%	3.83%	+13.92%
Volatility (6M) Calculated over the trailing 6-month period	88.07%	10.17%	+77.90%
Volatility (1Y) Calculated over the trailing 1-year period	198.96%	12.70%	+186.26%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	125.28%	16.05%	+109.23%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	122.16%	17.23%	+104.93%

Dividends

PRLD vs. VT - Dividend Comparison

PRLD has not paid dividends to shareholders, while VT's dividend yield for the trailing twelve months is around 1.59%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
PRLD Prelude Therapeutics Incorporated	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
VT Vanguard Total World Stock ETF	1.59%	1.82%	1.95%	2.08%	2.20%	1.82%	1.66%	2.32%	2.53%	2.11%	2.39%	2.45%

Frequently Asked Questions

Can I hold both PRLD and VT in my portfolio?

PRLD and VT have a correlation of 0.19, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, PRLD or VT?

PRLD has higher volatility (17.75%) compared to VT (3.83%). In terms of maximum drawdown, PRLD dropped -99.33% vs VT's -50.27%.

Which has better risk-adjusted returns?

VT currently has the higher Sharpe Ratio (2.31 vs 1.48), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.