PLX vs. AVLV

Last updated Jun 4, 2026

PLX (Protalix BioTherapeutics, Inc.) is a stock, while AVLV (Avantis U.S. Large Cap Value ETF) is Large Cap Value Equities fund tracking the Russell 1000 Value Index. Over the past 3 years, PLX returned -3.92%/yr vs 23.23%/yr for AVLV. At a 0.27 correlation, their price movements are largely independent.

Performance

PLX vs. AVLV - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Protalix BioTherapeutics, Inc. (PLX) and Avantis U.S. Large Cap Value ETF (AVLV). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, PLX achieves a 8.89% return, which is significantly lower than AVLV's 20.64% return.

PLX

• 1D: -1.51%
• 1M: -7.98%
• YTD: 8.89%
• 6M: 13.95%
• 1Y: 22.50%
• 3Y*: -3.92%
• 5Y*: -1.74%
• 10Y*: -13.01%

AVLV

• 1D: 0.14%
• 1M: 5.75%
• YTD: 20.64%
• 6M: 22.01%
• 1Y: 38.77%
• 3Y*: 23.23%
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

PLX vs. AVLV - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021
PLX Protalix BioTherapeutics, Inc.	8.89%	-4.26%	5.62%	29.93%	64.72%	-39.29%
AVLV Avantis U.S. Large Cap Value ETF	20.64%	15.12%	17.49%	17.43%	-5.53%	5.92%

Correlation

The correlation between PLX and AVLV is 0.33, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.33
Correlation (3Y) Calculated over the trailing 3-year period	0.28
Correlation (All Time) Calculated using the full available price history since Sep 24, 2021	0.27

Return for Risk

PLX vs. AVLV — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

PLX

PLX Risk / Return Rank: 53
PLX Sharpe Ratio Rank: 53
PLX Sortino Ratio Rank: 52
PLX Omega Ratio Rank: 52
PLX Calmar Ratio Rank: 54
PLX Martin Ratio Rank: 52

AVLV

AVLV Risk / Return Rank: 91
AVLV Sharpe Ratio Rank: 90
AVLV Sortino Ratio Rank: 91
AVLV Omega Ratio Rank: 89
AVLV Calmar Ratio Rank: 91
AVLV Martin Ratio Rank: 93

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

PLX vs. AVLV - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Protalix BioTherapeutics, Inc. (PLX) and Avantis U.S. Large Cap Value ETF (AVLV). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	PLX	AVLV	Difference
Sharpe ratio: Return per unit of total volatility	0.34	3.18	-2.84
Sortino ratio: Return per unit of downside risk	0.92	4.39	-3.47
Omega ratio: Gain probability vs. loss probability	1.12	1.57	-0.45
Calmar ratio: Return relative to maximum drawdown	0.57	6.09	-5.53
Martin ratio: Return relative to average drawdown	1.07	24.39	-23.31
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

PLX vs. AVLV - Sharpe Ratio Comparison

The current PLX Sharpe Ratio is 0.34, which is lower than the AVLV Sharpe Ratio of 3.18. The chart below compares the historical Sharpe Ratios of PLX and AVLV, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	PLX	AVLV	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	0.34	3.18	-2.84
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.03	—	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	-0.16	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.07	0.86	-0.93

Drawdowns

PLX vs. AVLV - Drawdown Comparison

The maximum PLX drawdown since its inception was -99.91%, which is greater than AVLV's maximum drawdown of -19.50%. Use the drawdown chart below to compare losses from any high point for PLX and AVLV.

Drawdown Indicators

	PLX	AVLV	Difference
Max Drawdown Largest peak-to-trough decline	-99.91%	-19.50%	-80.41%
Max Drawdown (1Y) Largest decline over 1 year	-39.68%	-6.39%	-33.29%
Max Drawdown (3Y) Largest decline over 3 years	-62.96%	-19.50%	-43.46%
Max Drawdown (5Y) Largest decline over 5 years	-73.21%	—	—
Max Drawdown (10Y) Largest decline over 10 years	-94.37%	—	—
Current Drawdown Current decline from peak	-99.78%	0.00%	-99.78%
Average Drawdown Average peak-to-trough decline	-93.66%	-3.93%	-89.73%
Ulcer Index Depth and duration of drawdowns from previous peaks	21.01%	1.59%	+19.42%

Volatility

PLX vs. AVLV - Volatility Comparison

Protalix BioTherapeutics, Inc. (PLX) has a higher volatility of 13.87% compared to Avantis U.S. Large Cap Value ETF (AVLV) at 3.12%. This indicates that PLX's price experiences larger fluctuations and is considered to be riskier than AVLV based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	PLX	AVLV	Difference
Volatility (1M) Calculated over the trailing 1-month period	13.87%	3.12%	+10.75%
Volatility (6M) Calculated over the trailing 6-month period	44.36%	9.04%	+35.32%
Volatility (1Y) Calculated over the trailing 1-year period	66.69%	12.29%	+54.40%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	67.72%	17.35%	+50.37%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	79.33%	17.35%	+61.98%

Dividends

PLX vs. AVLV - Dividend Comparison

PLX has not paid dividends to shareholders, while AVLV's dividend yield for the trailing twelve months is around 1.07%.

Position	TTM	2025	2024	2023	2022	2021
AVLV Avantis U.S. Large Cap Value ETF	1.07%	1.33%	1.58%	1.85%	2.00%	0.29%
PLX Protalix BioTherapeutics, Inc.	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Frequently Asked Questions

Can I hold both PLX and AVLV in my portfolio?

PLX and AVLV have a correlation of 0.33, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, PLX or AVLV?

PLX has higher volatility (13.87%) compared to AVLV (3.12%). In terms of maximum drawdown, PLX dropped -99.91% vs AVLV's -19.50%.

Which has better risk-adjusted returns?

AVLV currently has the higher Sharpe Ratio (3.17 vs 0.34), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.