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Protalix BioTherapeutics, Inc. (PLX)
Performance
Risk-Adjusted Performance
Dividends
Drawdowns
Volatility
Financials

Company Info

ISIN

US74365A3095

CUSIP

74365A309

IPO Date

May 15, 1998

Highlights

Market Cap

$126.58M

EPS (TTM)

$0.05

PE Ratio

31.80

PEG Ratio

-0.10

Total Revenue (TTM)

$59.76M

Gross Profit (TTM)

$29.87M

EBITDA (TTM)

$7.16M

Year Range

$0.82 - $3.10

Target Price

$14.00

Short %

1.28%

Short Ratio

0.73

Share Price Chart


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Protalix BioTherapeutics, Inc.

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Performance

Performance Chart


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S&P 500

Returns By Period

Protalix BioTherapeutics, Inc. (PLX) returned -17.55% year-to-date (YTD) and 35.96% over the past 12 months. Over the past 10 years, PLX returned -22.76% annually, underperforming the S&P 500 benchmark at 10.85%.


PLX

YTD

-17.55%

1M

-49.51%

6M

-9.88%

1Y

35.96%

3Y*

9.52%

5Y*

-14.23%

10Y*

-22.76%

^GSPC (Benchmark)

YTD

0.51%

1M

6.15%

6M

-2.00%

1Y

12.92%

3Y*

12.68%

5Y*

14.19%

10Y*

10.85%

*Annualized

Monthly Returns

The table below presents the monthly returns of PLX, with color gradation from worst to best to easily spot seasonal factors. Returns are adjusted for dividends.


JanFebMarAprMayJunJulAugSepOctNovDecTotal
202529.26%-4.12%9.87%19.92%-49.51%-17.55%
2024-18.54%12.41%-22.70%-9.52%-0.88%3.54%-7.69%-12.57%8.03%14.71%47.01%9.30%5.62%
202313.87%24.36%8.25%32.38%-24.82%-4.31%-20.00%18.12%-12.17%0.60%-9.58%17.88%29.93%
20221.25%-0.37%26.34%9.43%1.72%-7.63%-2.75%4.72%-6.18%-1.09%6.80%24.55%64.72%
202120.66%11.87%-8.98%-24.89%-9.25%-37.17%-20.94%8.61%-18.90%-15.04%-18.14%-10.09%-77.09%
202012.80%-10.81%-28.79%59.57%-10.93%13.47%-5.54%2.79%5.16%-15.50%9.79%1.11%10.67%
201956.27%-2.67%-6.98%-0.75%-15.27%26.76%-20.06%-44.68%-1.11%7.41%41.22%5.43%5.47%
20184.36%-2.81%-19.49%-24.06%18.49%-11.49%13.95%-2.02%51.41%-32.59%-11.53%-28.26%-52.96%
201741.55%66.69%29.52%-31.62%-3.26%-6.91%-18.81%-22.50%10.06%34.05%-11.25%-4.17%48.58%
2016-16.67%-2.12%1.02%-1.83%-3.04%-20.00%0.94%-7.43%-4.68%-17.53%19.12%-20.54%-56.37%
20158.70%-4.00%-7.29%23.60%-11.82%0.52%-15.90%-10.37%-19.73%-11.86%-0.00%-1.92%-44.57%
20149.25%13.65%-5.18%-11.57%-1.23%-8.75%-9.86%-20.97%-6.92%-9.09%-4.55%-12.38%-52.70%
Go deeper with the Portfolio Analysis tool — backtest performance, assess risk, compare to benchmarks, and more

Risk-Adjusted Performance

Risk-Adjusted Performance Rank

The current rank of PLX is 69, indicating average performance compared to other stocks on our website. Here’s a breakdown of how it compares using common performance measures.


The Risk-Adjusted Performance Rank of PLX is 6969
Overall Rank
The Sharpe Ratio Rank of PLX is 6868
Sharpe Ratio Rank
The Sortino Ratio Rank of PLX is 6767
Sortino Ratio Rank
The Omega Ratio Rank of PLX is 7272
Omega Ratio Rank
The Calmar Ratio Rank of PLX is 6666
Calmar Ratio Rank
The Martin Ratio Rank of PLX is 7272
Martin Ratio Rank
The risk-adjusted ranks indicate the investment's position relative to the market. A rank closer to 100 signifies top-performing investments, while a rank closer to 0 might suggest underperformance, based on the selected ratio. The values are calculated based on the past 12 months of returns.

Risk-Adjusted Performance Indicators

The charts below present risk-adjusted performance metrics for Protalix BioTherapeutics, Inc. (PLX) and compare them to a chosen benchmark (^GSPC). These indicators evaluate an investment's returns against its associated risks.


The Sharpe ratio helps investors understand how much return they're getting for the level of risk taken. A higher Sharpe ratio indicates better risk-adjusted performance, meaning more reward for each unit of risk.

Protalix BioTherapeutics, Inc. Sharpe ratios as of May 31, 2025 (values are recalculated daily):

  • 1-Year: 0.48
  • 5-Year: -0.21
  • 10-Year: -0.29
  • All Time: -0.08

These values reflect how efficiently the investment has delivered returns relative to its volatility over different time periods. All figures are annualized and based on daily total returns (including price changes and dividends).

The chart below shows the rolling Sharpe ratio of Protalix BioTherapeutics, Inc. compared to the selected benchmark. This view highlights how the investment's risk-adjusted performance has changed over time.


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Go to the full Sharpe Ratio tool to analyze any stock or portfolio. Customize time frames, set your own risk-free rate, and more

Dividends

Dividend History


Protalix BioTherapeutics, Inc. doesn't pay dividends

Drawdowns

Drawdowns Chart

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.


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Worst Drawdowns

The table below displays the maximum drawdowns of the Protalix BioTherapeutics, Inc.. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the Protalix BioTherapeutics, Inc. was 99.85%, occurring on Jan 27, 2022. The portfolio has not yet recovered.

The current Protalix BioTherapeutics, Inc. drawdown is 99.71%.


Depth

Start

To Bottom

Bottom

To Recover

End

Total

-99.85%Jun 15, 20063874Jan 27, 2022
-74.51%Dec 26, 200325Aug 11, 200513Dec 6, 200538
-46.67%Aug 8, 20031Aug 8, 20032Sep 15, 20033
-40%May 29, 20031May 29, 20031Jun 12, 20032
-40%Dec 11, 20031Dec 11, 20031Dec 15, 20032
Go to the full Drawdowns tool for more analysis options, including inflation-adjusted drawdowns, and more

Volatility

Volatility Chart

The chart below shows the rolling one-month volatility.


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Financials

Financial Performance

The chart below illustrates the trends in the financial health of Protalix BioTherapeutics, Inc. over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.


Annual
Quarterly

0.0

Earnings Per Share

The chart presents the Earnings Per Share (EPS) performance of Protalix BioTherapeutics, Inc., comparing actual results with analytics estimates. In the past quarter, the company did not meet analyst expectations for EPS, resulting in a surprise of -150.0%.


-0.30-0.20-0.100.000.100.2020212022202320242025
-0.05
-0.02
Actual
Estimate

Valuation

The Valuation section provides an overview of how Protalix BioTherapeutics, Inc. is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.


PE Ratio

The chart displays the Price-to-Earnings (P/E) ratio for PLX, comparing it with other companies in the Biotechnology industry. Currently, PLX has a P/E ratio of 31.8. This P/E ratio is significantly higher than those of industry peers. This could indicate that the stock is overvalued or that investors expect strong future growth.

PEG Ratio

The chart shows the Price/Earnings to Growth (PEG) ratio for PLX compared to other companies in the Biotechnology industry. PLX currently has a PEG ratio of -0.1. This PEG ratio is negative, which typically signals that the company's earnings are expected to decline. A negative PEG is not considered meaningful for valuation purposes.

PS Ratio

This chart shows the Price-to-Sales (P/S) ratio for PLX relative to other companies in the Biotechnology industry. Currently, PLX has a P/S ratio of 2.1. This P/S ratio is low compared to the industry average. It may indicate that the stock is undervalued relative to its revenue, or that the market expects slower growth or lower margins.

PB Ratio

The chart illustrates the Price-to-Book (P/B) ratio for PLX in comparison with other companies in the Biotechnology industry. Currently, PLX has a P/B value of 2.8. This P/B ratio is in line with the industry average, suggesting the stock is valued fairly in relation to its book value.

Income Statement



TTM
Revenue

Total Revenue

Cost Of Revenue

Gross Profit

Operating Expenses

Selling, General & Admin Expenses

R&D Expenses

Depreciation And Amortization

Total Operating Expenses

Income

Income Before Tax

Operating Income

EBITDA

EBIT

Earnings From Continuing Operations

Net Income

Income Tax Expense

Other Non-Operating Income (Expenses)

Extraordinary Items

Discontinued Operations

Effect Of Accounting Charges

Non Recurring

Minority Interest

Other Items

Interest Income

Interest Expense

Net Interest Income

Values in undefined except per share items